Výsledky vyhledávání - "Bettina E. Bauer"

A genetic screen identifies mutations in the yeast WAR1 gene, linking transcription factor phosphorylation to weak-acid stress adaptation

Autor: Chantal Schwartz, Angelika Kren, Christoph Schüller, Karl Kuchler, Christa Gregori, Bettina E. Bauer

Publikováno v: FEBS Journal. 274:3094-3107

Exposure of the yeast Saccharomyces cerevisiae to weak organic acids such as the food preservatives sorbate, benzoate and propionate leads to the pronounced induction of the plasma membrane ATP-binding cassette (ABC) transporter, Pdr12p. This protein

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::699bb4fab0a439f69f28db6659172b36
https://doi.org/10.1111/j.1742-4658.2007.05837.x

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Global Phenotypic Analysis and Transcriptional Profiling Defines the Weak Acid Stress Response Regulon inSaccharomyces cerevisiae

Autor: Christoph Schüller, Bettina E. Bauer, Mehdi Mollapour, Peter W. Piper, Michael K. Schuster, Yasmine M. Mamnun, Gerd Krapf, Karl Kuchler

Publikováno v: Molecular Biology of the Cell. 15:706-720

Weak organic acids such as sorbate are potent fungistatic agents used in food preservation, but their intracellular targets are poorly understood. We thus searched for potential target genes and signaling components in the yeast genome using contempo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d893242e3814571a2f7b6ca8c4362735
https://doi.org/10.1091/mbc.e03-05-0322

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Moderately lipophilic carboxylate compounds are the selective inducers of theSaccharomyces cerevisiaePdr12p ATP-binding cassette transporter

Autor: Karl Kuchler, Gerd Krapf, Peter W. Piper, Christoph Schüller, Kostas Hatzixanthis, Bettina E. Bauer, Ian J. Seymour, Mehdi Mollapour

Publikováno v: Yeast. 20:575-585

Saccharomyces cerevisiae displays very strong induction of a single ATP-binding cassette (ABC) transporter, Pdr12p, when stressed with certain weak organic acids. This is a plasma membrane pump catalysing active efflux of the organic acid anion from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::22c6def323f08081295adad8d886d218
https://doi.org/10.1002/yea.981

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Low levels of Ypt protein prenylation cause vesicle polarization defects and thermosensitive growth that can be suppressed by genes involved in cell wall maintenance

Autor: Urszula Bialek-Wyrzykowska, Antonella Ragnini, Bettina E. Bauer, Sepp D. Kohlwein, Wolfgang Wagner, Rudolf J. Schweyen

Publikováno v: Molecular Microbiology. 35:1295-1311

The Rab/Ypt small G proteins are essential for intracellular vesicle trafficking in mammals and yeast. The vesicle-docking process requires that Ypt proteins are located in the vesicle membrane. C-terminal geranylgeranyl anchors mediate the membrane

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a0a2af63df3039cc068234d241bc1c63
https://doi.org/10.1046/j.1365-2958.2000.01782.x

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Loss of Cmk1 Ca2+-calmodulin-dependent protein kinase in yeast results in constitutive weak organic acid resistance, associated with a post-transcriptional activation of the Pdr12 ATP-binding cassette transporter

Autor: Bettina E. Bauer, Claudia Ortiz Calderon, Kostas Hatzixanthis, Karl Kuchler, Caroline D. Holyoak, Suzanne Thompson, Peter W. Piper, Peter J. Coote

Publikováno v: Molecular Microbiology. 37:595-605

Yeast cells display an adaptive stress response when exposed to weak organic acids at low pH. This adaptation is important in the spoilage of preserved foods, as it allows growth in the presence of weak acid food preservatives. In Saccharomyces cerev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b6d296d0bf5f15ccdc13b2b7e49bc989
https://doi.org/10.1046/j.1365-2958.2000.02017.x

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Ypt protein prenylation depends on the interplay among levels of Rab escort protein and geranylgeranyl diphosphate in yeast cells

Autor: Wolfgang Wagner, Antonella Ragnini, Bettina E. Bauer, Marta Miaczynska, Rudolf J. Schweyen

Publikováno v: Yeast. 18:697-709

Farnesyl diphosphate (FPP), an intermediate of the sterol biosynthetic pathway, is used by farnesyl transferase to farnesylate, among others, the Ras proteins, and by geranylgeranyl diphosphate synthase to produce geranylgeranyl diphosphate (GGPP). G

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7933efd02aa88a231dca6083d9ea61a
https://doi.org/10.1002/yea.719

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Positive and Negative Control of Multidrug Resistance by the Sit4 Protein Phosphatase in Kluyveromyces lactis

Autor: Xin Jie Chen, George Desmond Clark-Walker, Bettina E. Bauer, Karl Kuchler

Publikováno v: Journal of Biological Chemistry. 275:14865-14872

The nuclear gene encoding the Sit4 protein phosphatase was identified in the budding yeast Kluyveromyces lactis. K. lactis cells carrying a disrupted sit4 allele are resistant to oligomycin, antimycin, ketoconazole, and econazole but hypersensitive t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb1dda2e858ceac43886062409a5fd2f
https://doi.org/10.1074/jbc.275.20.14865

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Amino- and carboxy-terminal domains of the yeast Rab escort protein are both required for binding of Ypt small G proteins

Autor: Bettina E. Bauer, Antonella Ragnini, Rudolf J. Schweyen, Duc Minh Bui, Marta Miaczynska, Stefano Lorenzetti

Publikováno v: Scopus-Elsevier

The Rab escort protein (REP) is an essential component of the heterotrimeric enzyme Rab geranylgeranyl transferase that modifies the carboxy-terminal cysteines of the Ras-like small G proteins belonging to the Rab/Ypt family. Deletions in the human C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a4e07e3f62e57c2489dcb258c0a0fd1
https://doi.org/10.1091/mbc.7.10.1521

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Weak organic acid stress inhibits aromatic amino acid uptake by yeast, causing a strong influence of amino acid auxotrophies on the phenotypes of membrane transporter mutants

Autor: Danielle Rossington, Yasmine M. Mamnun, Bettina E. Bauer, Mehdi Mollapour, Karl Kuchler, Peter W. Piper

Publikováno v: European journal of biochemistry. 270(15)

The ability of yeasts to grow in the presence of weak organic acid preservatives is an important cause of food spoilage. Many of the determinants of acetate resistance in Saccharomyces cerevisiae differ from the determinants of resistance to the more

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48ae1979ae7b9555b4920f268c7de57b
https://pubmed.ncbi.nlm.nih.gov/12869194

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Moderately lipophilic carboxylate compounds are the selective inducers of the Saccharomyces cerevisiae Pdr12p ATP-binding cassette transporter

Autor: Kostas, Hatzixanthis, Mehdi, Mollapour, Ian, Seymour, Bettina E, Bauer, Gerd, Krapf, Christoph, Schüller, Karl, Kuchler, Peter W, Piper

Publikováno v: Yeast (Chichester, England). 20(7)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e68c5d4e21f022a4f759bf12274f7946
https://pubmed.ncbi.nlm.nih.gov/12734796

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