Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Bettina E. B. Jensen"'
Publikováno v:
The Journal of Physical Chemistry. B
Jensen, B E B, Davila, I & Zelikin, A N 2016, ' Poly(vinyl alcohol) Physical Hydrogels : Matrix-Mediated Drug Delivery Using Spontaneously Eroding Substrate ', Journal of Physical Chemistry Part B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical, vol. 120, no. 26, pp. 5916-5926 . https://doi.org/10.1021/acs.jpcb.6b01381
Jensen, B E B, Davila, I & Zelikin, A N 2016, ' Poly(vinyl alcohol) Physical Hydrogels : Matrix-Mediated Drug Delivery Using Spontaneously Eroding Substrate ', Journal of Physical Chemistry Part B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical, vol. 120, no. 26, pp. 5916-5926 . https://doi.org/10.1021/acs.jpcb.6b01381
Poly(vinyl alcohol) hydrogels have a long and successful history of applications in biomedicine. Historically, these matrices were developed to be nondegradable limiting their utility to applications as permanent implants. For tissue engineering and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b37bc256cce3c9788b278a74156ccf0c
https://doi.org/10.1021/acs.jpcb.6b01381
https://doi.org/10.1021/acs.jpcb.6b01381
Publikováno v:
Wohl, B, Smith, A A A, Jensen, B E B & Zelikin, A N 2014, ' Macromolecular (pro)drugs with concurrent direct activity against the hepatitis C virus and inflammation ', Journal of Controlled Release, vol. 196, pp. 197–207 . https://doi.org/10.1016/j.jconrel.2014.09.032
Macromolecular prodrugs (MPs) are a powerful tool to alleviate side-effects and improve the efficacy of the broad-spectrum antiviral agent ribavirin. In this work, we sought an understanding of what makes an optimal formulation within the macromolecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbcd40167316281ff32b5696633edfd6
https://doi.org/10.1016/j.jconrel.2014.09.032
https://doi.org/10.1016/j.jconrel.2014.09.032
Autor:
Anton A. A. Smith, Bettina E. B. Jensen, Alexander N. Zelikin, Leticia Hosta-Rigau, Marie Baekgaard Laursen, Martin E. Lynge, Ryosuke Ogaki, Brigitte Städler
Publikováno v:
Madsen, M E L, Laursen, M B, Rigau, L H, Jensen, B E B, Ogaki, R, Smith, A A A, Zelikin, A N & Stadler, B M 2013, ' Liposomes as Drug Deposits in Multilayered Polymer Films ', A C S Applied Materials and Interfaces, vol. 5, no. 8, pp. 2967-2975 . https://doi.org/10.1021/am4006868
The ex vivo growth of implantable hepatic or cardiac tissue remains a challenge and novel approaches are highly sought after. We report an approach to use liposomes embedded within multilayered films as drug deposits to deliver active cargo to adhere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3493724a37aa83ce5c81bdde3144658
https://doi.org/10.1021/am4006868
https://doi.org/10.1021/am4006868
Autor:
Almar Postma, Kenneth N. Goldie, Bettina E. B. Jensen, Alexander N. Zelikin, Siow-Feng Chong, Brigitte Städler, Sidsel Ø. Andreasen, Mille B. L. Kryger, Marie-Helene Alves
Publikováno v:
Andreasen, S Ø, Chong, S F, Kryger, M, Jensen, B E B, Postma, A, Alves, M-H, Stadler, B M, Goldie, K & Zelikin, A N 2013, ' Liposomal Templating, Association with Mammalian Cells, and Cytotoxicity of Poly(vinyl alcohol) Physical Hydrogel Nanoparticles ', Particle & Particle Systems Characterization, vol. 30, no. 6, pp. 514-522 . https://doi.org/10.1002/ppsc.201200134
The assembly, cellular internalization, and cytotoxicity of nanoparticles based on physical hydrogels of poly(vinyl alcohol) (PVA) are reported. PVA nanoparticles are assembled using a liposomal templating technique followed by removal of the lipids
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f742464fada64d1d4cace67b5450546b
https://doi.org/10.1002/ppsc.201200134
https://doi.org/10.1002/ppsc.201200134
Publikováno v:
Macromolecular Bioscience. 11:1293-1313
Poly(vinyl alcohol), PVA, and physical hydrogels derived thereof have an excellent safety profile and a successful history of biomedical applications. However, these materials are hardly in the focus of biomedical research, largely due to poor opport
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfd1f2fe27d303d8e0bf29af6bb37c73
https://doi.org/10.1002/mabi.201100145
https://doi.org/10.1002/mabi.201100145
Publikováno v:
Jensen, B E B, Edlund, K & Zelikin, A N 2015, ' Micro-structured, spontaneously eroding hydrogels accelerate endothelialization through presentation of conjugated growth factors ', Biomaterials, vol. 49, pp. 113-124 . https://doi.org/10.1016/j.biomaterials.2015.01.036
Growth factors represent highly potent and highly efficacious means of communication to cells. At the same time, these proteins are fragile and relatively small sized rendering their immobilization and controlled release from biomaterials challenging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22d076e40f8b5da4f685185064ed6eca
https://pure.au.dk/portal/da/publications/microstructured-spontaneously-eroding-hydrogels-accelerate-endothelialization-through-presentation-of-conjugated-growth-factors(3776a965-805d-4678-bf06-b91d88ada35a).html
https://pure.au.dk/portal/da/publications/microstructured-spontaneously-eroding-hydrogels-accelerate-endothelialization-through-presentation-of-conjugated-growth-factors(3776a965-805d-4678-bf06-b91d88ada35a).html
Autor:
Thomas Hussmann, Bettina E. B. Jensen, Anton A. A. Smith, Alexander N. Zelikin, Betina Fejerskov
Publikováno v:
Fejerskov, B, Smith, A A A, Jensen, B E B, Hussmann, T & Zelikin, A N 2013, ' Bioresorbable Surface-Adhered Enzymatic Microreactors Based on Physical Hydrogels of Poly(vinyl alcohol) ', Langmuir, vol. 29, no. 1, pp. 344-54 . https://doi.org/10.1021/la3040903
Hydrogel biomaterials based on poly(vinyl alcohol), PVA, have an extensive history of biomedical applications, yet in their current form suffer from significant shortcomings, such as a lack of mechanism of biodegradation and poor opportunities in con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3668fd55700a2a07d8a150b2af463b7f
https://pure.au.dk/portal/da/publications/bioresorbable-surfaceadhered-enzymatic-microreactors-based-on-physical-hydrogels-of-polyvinyl-alcohol(b255413e-6abf-4926-8349-f87b9f2b9b4c).html
https://pure.au.dk/portal/da/publications/bioresorbable-surfaceadhered-enzymatic-microreactors-based-on-physical-hydrogels-of-polyvinyl-alcohol(b255413e-6abf-4926-8349-f87b9f2b9b4c).html
Autor:
Meifang Zhu, Karthiga Panneerselvam, Leticia Hosta-Rigau, Yan Zhang, Ryosuke Ogaki, Rebecca van der Westen, Brigitte Städler, Boon M. Teo, Bettina E. B. Jensen
Publikováno v:
Zhang, Y, Panneerselvam, K, Ogaki, R, Rigau, L H, van der westen, R, Jensen, B E B, Mian Teo, B, Zhu, M & Stadler, B M 2013, ' Assembly of Poly(dopamine)/Poly(N-isopropyl acrylamide) Mixed Films and their Temperature Dependent Interaction with Proteins, Liposomes and Cells ', Langmuir, vol. 29, no. 32, pp. 10213-10222 . https://doi.org/10.1021/la402118u
Many biomedical applications benefit from responsive polymer coatings. The properties of poly(dopamine) (PDA) films can be affected by codepositing dopamine (DA) with the temperature-responsive polymer poly(N-isopropylacrylamide) (pNiPAAm). We charac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a2bc4d55a3327e0f5862100f5383fe8
https://pure.au.dk/portal/da/publications/assembly-of-polydopaminepolynisopropyl-acrylamide-mixed-films-and-their-temperature-dependent-interaction-with-proteins-liposomes-and-cells(f969e662-3e80-4013-88ad-7255fdfb967b).html
https://pure.au.dk/portal/da/publications/assembly-of-polydopaminepolynisopropyl-acrylamide-mixed-films-and-their-temperature-dependent-interaction-with-proteins-liposomes-and-cells(f969e662-3e80-4013-88ad-7255fdfb967b).html
Autor:
Marcel Ceccato, Kim Daasbjerg, Kyoko Shimizu, Sergey Chernyy, Joseph Iruthayaraj, Bettina E. B. Jensen, Alexander N. Zelikin, Steen Uttrup Pedersen
Publikováno v:
Chernyy, S, Jensen, B E B, Shimizu, K, Ceccato, M, Pedersen, S U, Zelikin, A N, Daasbjerg, K & Iruthayaraj, J 2013, ' Surface Grafted Glycopolymer Brushes to Enhance Selective Adhesion of HepG2 Cells ', Journal of Colloid and Interface Science, vol. 404, pp. 207–214 . https://doi.org/10.1016/j.jcis.2013.04.025
This work demonstrates the application of carbohydrate based methacrylate polymer brush, poly(2-lactobionamidoethyl methacrylate), for the purpose of cell adhesion studies. The first part of the work illustrates the effects of the structure of the am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9fdf6bc05879d26100091b59462cdfc
https://pure.au.dk/portal/da/publications/surface-grafted-glycopolymer-brushes-to-enhance-selective-adhesion-of-hepg2-cells(0f4051f3-ebc2-4346-a922-ccc6730b08b6).html
https://pure.au.dk/portal/da/publications/surface-grafted-glycopolymer-brushes-to-enhance-selective-adhesion-of-hepg2-cells(0f4051f3-ebc2-4346-a922-ccc6730b08b6).html
Autor:
Najah B. S. Jensen, Bettina E. B. Jensen, Alexander N. Zelikin, Betina Fejerskov, Siow-Feng Chong
Publikováno v:
Fejerskov, B, Jensen, B E B, Jensen, N B S, Chong, S F & Zelikin, A N 2012, ' Engineering surface adhered poly(vinyl alcohol) physical hydrogels as enzymatic microreactors ', A C S Applied Materials and Interfaces, vol. 4, no. 9, pp. 4981-90 . https://doi.org/10.1021/am3013467
In this work, we characterize physical hydrogels based on poly(vinyl alcohol), PVA, as intelligent biointerfaces for surface-mediated drug delivery. Specifically, we assemble microstructured (μS) surface adhered hydrogels via noncryogenic gelation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8348b6e7534a514e31d61a022c1bc023
https://pure.au.dk/portal/da/publications/engineering-surface-adhered-polyvinyl-alcohol-physical-hydrogels-as-enzymatic-microreactors(686cec00-62c9-4806-ad73-34e88ff2cb85).html
https://pure.au.dk/portal/da/publications/engineering-surface-adhered-polyvinyl-alcohol-physical-hydrogels-as-enzymatic-microreactors(686cec00-62c9-4806-ad73-34e88ff2cb85).html