Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Bettina A. Moser"'
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
A functional telomerase complex requires that the catalytic TERT subunit be assembled with the template RNA TER1. Here the authors show that Pof8, a possible LARP7 family protein, is required for assembly of the telomerase complex, and repression of
Externí odkaz:
https://doaj.org/article/75e94b3c5a5045c4a231fd702af774f5
Publikováno v:
PLoS Genetics, Vol 13, Iss 5, p e1006776 (2017)
The posttranslational modifiers SUMO and ubiquitin critically regulate the DNA damage response (DDR). Important crosstalk between these modifiers at DNA lesions is mediated by the SUMO-targeted ubiquitin ligase (STUbL), which ubiquitinates SUMO chain
Externí odkaz:
https://doaj.org/article/eb8e9db6e7874713af428665ee3c8e6e
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Nature Communications
Nature Communications
Telomerase is a reverse transcriptase complex that ensures stable maintenance of linear eukaryotic chromosome ends by overcoming the end replication problem, posed by the inability of replicative DNA polymerases to fully replicate linear DNA. The cat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65fb792777ef782f5b1c7032de806146
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 13, Iss 5, p e1006776 (2017)
PLoS Genetics, Vol 13, Iss 5, p e1006776 (2017)
The posttranslational modifiers SUMO and ubiquitin critically regulate the DNA damage response (DDR). Important crosstalk between these modifiers at DNA lesions is mediated by the SUMO-targeted ubiquitin ligase (STUbL), which ubiquitinates SUMO chain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2d59577f578bce9f339204f91e92af9
Publikováno v:
PLoS Genetics, Vol 10, Iss 10, p e1004708 (2014)
In both fission yeast and humans, the shelterin complex plays central roles in regulation of telomerase recruitment, protection of telomeres against DNA damage response factors, and formation of heterochromatin at telomeres. While shelterin is essent
Externí odkaz:
https://doaj.org/article/2e9a36c9c1664281b13db5c8e7b850c9
Publikováno v:
PLoS Genetics, Vol 9, Iss 11, p e1003936 (2013)
Studies in fission yeast have previously identified evolutionarily conserved shelterin and Stn1-Ten1 complexes, and established Rad3(ATR)/Tel1(ATM)-dependent phosphorylation of the shelterin subunit Ccq1 at Thr93 as the critical post-translational mo
Externí odkaz:
https://doaj.org/article/37b86796c0d7488ab32e7ef8b0c6f879
Autor:
Caroline Durrant, Gabriele Schönian, Abdelmajeed Nasereddin, Hideo Imamura, Bettina A. Moser, Tapan Bhattacharyya, Matthew Berriman, Mohammad Zahangeer Alam, Thierry Wirth, Susanne U. Franssen, Henk D. F. H. Schallig, Michael A. Miles, Tim Downing, Jean-Claude Dujardin, James Cotton, Matthew Yeo, Lionel F. Schnur, Charles L. Jaffe, Olivia Stark, Isabel Mauricio, Mandy Sanders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcf752751d4f83fb77ccff51112ed782
https://doi.org/10.7554/elife.51243.sa2
https://doi.org/10.7554/elife.51243.sa2
Autor:
Bettina A. Moser, Ross S. Low, Alice Hoyle, Katsunori Tanaka, Amanda K. Mennie, Toru Nakamura
Publikováno v:
Communications Biology, Vol 2, Iss 1, Pp 1-15 (2019)
In both mammalian and fission yeast cells, conserved shelterin and CST (CTC1-STN1-TEN1) complexes play critical roles in protection of telomeres and regulation of telomerase, an enzyme required to overcome the end replication problem. However, molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d84578db28331c17179af243331838b0
https://doi.org/10.1038/s42003-019-0546-8
https://doi.org/10.1038/s42003-019-0546-8
Autor:
Mohammad Zahangir Alam, Matthew Yeo, Bettina A. Moser, Tapan Bhattacharyya, Susanne U. Franssen, Michael A. Miles, Abdelmajeed Nasereddin, Mandy Sanders, Olivia Stark, Isabel Mauricio, Tim Downing, Charles L. Jaffe, Thierry Wirth, Lionel F. Schnur, James Cotton, Gabriele Schönian, Jean-Claude Dujardin, Matthew Berriman, Hideo Imamura, Caroline Durrant, Henk D. F. H. Schallig
Publikováno v:
eLife
eLife, eLife Sciences Publication, 2020, 9, ⟨10.7554/eLife.51243⟩
eLife, 9:e51243. eLife Sciences Publications
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
eLife, Vol 9 (2020)
eLife, eLife Sciences Publication, 2020, 9, ⟨10.7554/eLife.51243⟩
eLife, 9:e51243. eLife Sciences Publications
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
eLife, Vol 9 (2020)
Protozoan parasites of theLeishmania donovanicomplex –L. donovaniandL. infantum– cause the fatal disease visceral leishmaniasis. We present the first comprehensive genome-wide global study, with 151 cultured field isolates representing most of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83c8adc75622cb1e89568114d7bed5c1
Autor:
Amanda K, Mennie, Bettina A, Moser, Alice, Hoyle, Ross S, Low, Katsunori, Tanaka, Toru M, Nakamura
Publikováno v:
Communications Biology
In both mammalian and fission yeast cells, conserved shelterin and CST (CTC1-STN1-TEN1) complexes play critical roles in protection of telomeres and regulation of telomerase, an enzyme required to overcome the end replication problem. However, molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::efdc1d40e7dd63e98955e7ef4589bd9d
https://pubmed.ncbi.nlm.nih.gov/31396577
https://pubmed.ncbi.nlm.nih.gov/31396577