Zobrazeno 1 - 10
of 379
pro vyhledávání: '"Bettina, Warscheid"'
Autor:
Corinne von Känel, Philip Stettler, Carmela Esposito, Stephan Berger, Simona Amodeo, Silke Oeljeklaus, Salvatore Calderaro, Ignacio M Durante, Vendula Rašková, Bettina Warscheid, André Schneider
Publikováno v:
PLoS Biology, Vol 22, Iss 8, p e3002449 (2024)
Protein import and genome replication are essential processes for mitochondrial biogenesis and propagation. The J-domain proteins Pam16 and Pam18 regulate the presequence translocase of the mitochondrial inner membrane. In the protozoan Trypanosoma b
Externí odkaz:
https://doaj.org/article/64ab8f152b6f436f85439cad12bc2318
Autor:
Fan Xu, Ruoyao Li, Erika D. von Gromoff, Friedel Drepper, Bettina Knapp, Bettina Warscheid, Ralf Baumeister, Wenjing Qi
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Transient stress experiences not only trigger acute stress responses, but can also have long-lasting effects on cellular functions. In Caenorhabditis elegans, a brief exposure to heat shock during early adulthood extends lifespan and improve
Externí odkaz:
https://doaj.org/article/6404d3763443407bb78ebbe1d3817305
Autor:
Minji Kim, Remigiusz A. Serwa, Lukasz Samluk, Ida Suppanz, Agata Kodroń, Tomasz M. Stępkowski, Praveenraj Elancheliyan, Biniyam Tsegaye, Silke Oeljeklaus, Michal Wasilewski, Bettina Warscheid, Agnieszka Chacinska
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-23 (2023)
Abstract Perturbed cellular protein homeostasis (proteostasis) and mitochondrial dysfunction play an important role in neurodegenerative diseases, however, the interplay between these two phenomena remains unclear. Mitochondrial dysfunction leads to
Externí odkaz:
https://doaj.org/article/c2fd6721e8ef407e965945401da63108
Autor:
Florian Becker, Simon Fuchs, Lukas Refisch, Friedel Drepper, Wolfgang Bildl, Uwe Schulte, Shuo Liang, Jonas Immanuel Heinicke, Sierra C Hansen, Clemens Kreutz, Bettina Warscheid, Bernd Fakler, Evgeny V Mymrikov, Carola Hunte
Publikováno v:
eLife, Vol 12 (2023)
Calcineurin B homologous protein 3 (CHP3) is an EF-hand Ca2+-binding protein involved in regulation of cancerogenesis, cardiac hypertrophy, and neuronal development through interactions with sodium/proton exchangers (NHEs) and signalling proteins. Wh
Externí odkaz:
https://doaj.org/article/bdcb900445214a9b841db465955cec1f
Autor:
Caroline E. Dewar, Silke Oeljeklaus, Jan Mani, Wignand W. D. Mühlhäuser, Corinne von Känel, Johannes Zimmermann, Torsten Ochsenreiter, Bettina Warscheid, André Schneider
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Mitochondria import most of their proteins posttranslationally. Here, Dewar et al. characterize the mitochondrial quality control mechanism of Trypanosoma brucei. Through proteomics and functional studies, they show that only ablation of ATOM69, one
Externí odkaz:
https://doaj.org/article/3b2387b2f9184a889fa3ce9cdccdc488
Autor:
Natalie Thuma, Daniela Döhler, Dirk Mielenz, Heinrich Sticht, Daniel Radtke, Lena Reimann, Bettina Warscheid, David Voehringer
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Hookworms infect more that 400 million people and cause significant socio-economic burden on endemic countries. The lack of efficient vaccines and the emergence of anthelminthic drug resistance are of major concern. Free-living hookworm larvae infect
Externí odkaz:
https://doaj.org/article/06fd5f6d76fa48ee81f6ad6763de2d1a
Autor:
Bernd Schimanski, Salome Aeschlimann, Philip Stettler, Sandro Käser, Maria Gomez-Fabra Gala, Julian Bender, Bettina Warscheid, F-Nora Vögtle, André Schneider
Publikováno v:
PLoS Pathogens, Vol 18, Iss 6, p e1010207 (2022)
The protist parasite Trypanosoma brucei has a single mitochondrion with a single unit genome termed kinetoplast DNA (kDNA). Faithfull segregation of replicated kDNA is ensured by a complicated structure termed tripartite attachment complex (TAC). The
Externí odkaz:
https://doaj.org/article/da159221ac3a4a81b4191be7262d143d
Autor:
Advaitha Iyer, Moritz Niemann, Mauro Serricchio, Caroline E Dewar, Silke Oeljeklaus, Luce Farine, Bettina Warscheid, André Schneider, Peter Bütikofer
Publikováno v:
PLoS Pathogens, Vol 18, Iss 5, p e1009717 (2022)
The endoplasmic reticulum membrane complex (EMC) is a versatile complex that plays a key role in membrane protein biogenesis in the ER. Deletion of the complex has wide-ranging consequences including ER stress, disturbance in lipid transport and orga
Externí odkaz:
https://doaj.org/article/edba199df9bf463bb92e660f78d35e86
Autor:
Sven Dennerlein, Sabine Poerschke, Silke Oeljeklaus, Cong Wang, Ricarda Richter-Dennerlein, Johannes Sattmann, Diana Bauermeister, Elisa Hanitsch, Stefan Stoldt, Thomas Langer, Stefan Jakobs, Bettina Warscheid, Peter Rehling
Publikováno v:
eLife, Vol 10 (2021)
Human mitochondria express a genome that encodes thirteen core subunits of the oxidative phosphorylation system (OXPHOS). These proteins insert into the inner membrane co-translationally. Therefore, mitochondrial ribosomes engage with the OXA1L-inser
Externí odkaz:
https://doaj.org/article/e8625a3117ca49bd95b34fa7d3c7007d
Autor:
Christoph Wenger, Anke Harsman, Moritz Niemann, Silke Oeljeklaus, Corinne von Känel, Salvatore Calderaro, Bettina Warscheid, André Schneider
Publikováno v:
Molecular Microbiology. 119:537-550
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::253a0bc191d79379ed4eca987e7b8575
https://doi.org/10.1111/mmi.15048
https://doi.org/10.1111/mmi.15048