Ube3a unsilencer for the potential treatment of Angelman syndrome.

Autor: Vihma H; Department of Cell Biology and Physiology, Neuroscience Center, and Carolina Institute for Developmental Disabilities, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Li K; Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Welton-Arndt A; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Smith AL; Department of Cell Biology and Physiology, Neuroscience Center, and Carolina Institute for Developmental Disabilities, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Bettadapur KR; Department of Cell Biology and Physiology, Neuroscience Center, and Carolina Institute for Developmental Disabilities, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Gilmore RB; Department of Genetics and Genome Sciences, University of Connecticut School of Medicine, Farmington, CT, USA., Gao E; Department of Cell Biology and Physiology, Neuroscience Center, and Carolina Institute for Developmental Disabilities, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Cotney JL; Department of Genetics and Genome Sciences, University of Connecticut School of Medicine, Farmington, CT, USA., Huang HC; Deerfield Discovery and Development, Deerfield Management, New York, NY, USA., Collins JL; Office of the Vice Chancellor for Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Chamberlain SJ; Department of Genetics and Genome Sciences, University of Connecticut School of Medicine, Farmington, CT, USA., Lee HM; Department of Cell Biology and Physiology, Neuroscience Center, and Carolina Institute for Developmental Disabilities, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. dr.hmlee@gmail.com.; Department of Biochemistry and Molecular Biology, Hollings Cancer Center, Medical University of South Carolina, Charleston, SC, USA. dr.hmlee@gmail.com., Aubé J; Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. jaube@email.unc.edu.; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. jaube@email.unc.edu., Philpot BD; Department of Cell Biology and Physiology, Neuroscience Center, and Carolina Institute for Developmental Disabilities, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. bphilpot@med.unc.edu.

Publikováno v: Nature communications [Nat Commun] 2024 Jul 08; Vol. 15 (1), pp. 5558. Date of Electronic Publication: 2024 Jul 08.

Weak Directing Group Steered Formal Oxidative [2+2+2]-Cyclization for Selective Benzannulation of Indoles.

Autor: Bettadapur KR; Department of Organic Chemistry, Indian Institute of Science , Bangalore 560 012, Karnataka India., Kapanaiah R; Department of Organic Chemistry, Indian Institute of Science , Bangalore 560 012, Karnataka India., Lanke V; Department of Organic Chemistry, Indian Institute of Science , Bangalore 560 012, Karnataka India., Prabhu KR; Department of Organic Chemistry, Indian Institute of Science , Bangalore 560 012, Karnataka India.

Publikováno v: The Journal of organic chemistry [J Org Chem] 2018 Feb 16; Vol. 83 (4), pp. 1810-1818. Date of Electronic Publication: 2018 Jan 31.

Electronic Nature of Ketone Directing Group as a Key To Control C-2 vs C-4 Alkenylation of Indoles.

Autor: Lanke V; Department of Organic Chemistry, Indian Institute of Science , Bangalore 560 012, Karnataka, India., Bettadapur KR; Department of Organic Chemistry, Indian Institute of Science , Bangalore 560 012, Karnataka, India., Prabhu KR; Department of Organic Chemistry, Indian Institute of Science , Bangalore 560 012, Karnataka, India.

Publikováno v: Organic letters [Org Lett] 2016 Nov 04; Vol. 18 (21), pp. 5496-5499. Date of Electronic Publication: 2016 Oct 13.

Ru (II)-Catalyzed C-H Activation: Ketone-Directed Novel 1,4-Addition of Ortho C-H Bond to Maleimides.

Autor: Bettadapur KR; Department of Organic Chemistry, Indian Institute of Science , Bangalore 560 012, Karnataka, India., Lanke V; Department of Organic Chemistry, Indian Institute of Science , Bangalore 560 012, Karnataka, India., Prabhu KR; Department of Organic Chemistry, Indian Institute of Science , Bangalore 560 012, Karnataka, India.

Publikováno v: Organic letters [Org Lett] 2015 Oct 02; Vol. 17 (19), pp. 4658-61. Date of Electronic Publication: 2015 Sep 08.