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UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome.

Autor: Hjerpe R; Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, Davidson Building, Henry Wellcome Lab of Cell Biology, University of Glasgow, G12 8QQ Glasgow, UK; The MRC Protein Phosphorylation and Ubiquitylation Unit, The Sir James Black Centre, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland., Bett JS; Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, Davidson Building, Henry Wellcome Lab of Cell Biology, University of Glasgow, G12 8QQ Glasgow, UK; The MRC Protein Phosphorylation and Ubiquitylation Unit, The Sir James Black Centre, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland. Electronic address: johnsbett@yahoo.co.uk., Keuss MJ; The MRC Protein Phosphorylation and Ubiquitylation Unit, The Sir James Black Centre, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland., Solovyova A; Newcastle University Protein and Proteome Analysis, Devonshire Building, Devonshire Terrace, Newcastle upon Tyne NE1 7RU, UK., McWilliams TG; The MRC Protein Phosphorylation and Ubiquitylation Unit, The Sir James Black Centre, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland., Johnson C; The MRC Protein Phosphorylation and Ubiquitylation Unit, The Sir James Black Centre, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland., Sahu I; Department of Biology, Technion-Israel Institute of Technology, 32000 Haifa, Israel., Varghese J; The MRC Protein Phosphorylation and Ubiquitylation Unit, The Sir James Black Centre, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland., Wood N; The MRC Protein Phosphorylation and Ubiquitylation Unit, The Sir James Black Centre, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland., Wightman M; The MRC Protein Phosphorylation and Ubiquitylation Unit, The Sir James Black Centre, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland., Osborne G; Department of Medical and Molecular Genetics, King's College London, 8th Floor Tower Wing, Guy's Hospital, Great Maze Pond, London SE1 9RT, UK., Bates GP; Department of Medical and Molecular Genetics, King's College London, 8th Floor Tower Wing, Guy's Hospital, Great Maze Pond, London SE1 9RT, UK., Glickman MH; Department of Biology, Technion-Israel Institute of Technology, 32000 Haifa, Israel., Trost M; The MRC Protein Phosphorylation and Ubiquitylation Unit, The Sir James Black Centre, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland., Knebel A; The MRC Protein Phosphorylation and Ubiquitylation Unit, The Sir James Black Centre, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland., Marchesi F; School of Veterinary Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, 464 Bearsden Road, Glasgow G61 1QH, UK., Kurz T; Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, Davidson Building, Henry Wellcome Lab of Cell Biology, University of Glasgow, G12 8QQ Glasgow, UK; The MRC Protein Phosphorylation and Ubiquitylation Unit, The Sir James Black Centre, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland. Electronic address: thimo.kurz@glasgow.ac.uk.

Publikováno v: Cell [Cell] 2016 Aug 11; Vol. 166 (4), pp. 935-949. Date of Electronic Publication: 2016 Jul 28.

SiRNA screening to identify ubiquitin and ubiquitin-like system regulators of biological pathways in cultured mammalian cells.

Autor: Bett JS; MRC Protein Phosphorylation and Ubiquitylation Unit, College of Life Sciences, University of Dundee; j.s.bett@dundee.ac.uk., Ibrahim AF; MRC Protein Phosphorylation and Ubiquitylation Unit, College of Life Sciences, University of Dundee., Garg AK; MRC Protein Phosphorylation and Ubiquitylation Unit, College of Life Sciences, University of Dundee., Rocha S; Centre for Gene Regulation and Expression, College of Life Sciences, University of Dundee., Hay RT; MRC Protein Phosphorylation and Ubiquitylation Unit, College of Life Sciences, University of Dundee; Centre for Gene Regulation and Expression, College of Life Sciences, University of Dundee.

Publikováno v: Journal of visualized experiments : JoVE [J Vis Exp] 2014 May 24 (87). Date of Electronic Publication: 2014 May 24.

Suppression of protein aggregation by chaperone modification of high molecular weight complexes.

Autor: Labbadia J; Department of Medical and Molecular Genetics, King’s College London, London SE1 9RT, UK., Novoselov SS, Bett JS, Weiss A, Paganetti P, Bates GP, Cheetham ME

Publikováno v: Brain : a journal of neurology [Brain] 2012 Apr; Vol. 135 (Pt 4), pp. 1180-96. Date of Electronic Publication: 2012 Mar 06.

The polyubiquitin Ubc gene modulates histone H2A monoubiquitylation in the R6/2 mouse model of Huntington's disease.

Autor: Bett JS; King's College London School of Medicine, Department of Medical and Molecular Genetics, King's College London, London, United Kingdom., Benn CL; King's College London School of Medicine, Department of Medical and Molecular Genetics, King's College London, London, United Kingdom., Ryu KY; Department of Biological Sciences, Stanford University, Stanford, CA, USA., Kopito RR; Department of Biological Sciences, Stanford University, Stanford, CA, USA., Bates GP; King's College London School of Medicine, Department of Medical and Molecular Genetics, King's College London, London, United Kingdom.

Publikováno v: Journal of cellular and molecular medicine [J Cell Mol Med] 2009 Aug; Vol. 13 (8B), pp. 2645-2657.