Výsledky vyhledávání - "Betsy L. Pilmer"

Withdrawing PPI Therapy After Healing Esophagitis Does Not Worsen Symptoms or Cause Persistent Hypergastrinemia: Analysis of Dexlansoprazole MR Clinical Trial Data

Autor: Cong Han, Betsy L. Pilmer, David C. Metz, M. Claudia Perez

Publikováno v: The American Journal of Gastroenterology

OBJECTIVES: Withdrawal of proton pump inhibitors (PPIs) may induce symptoms in healthy volunteers, suggesting that discontinuing PPI therapy induces acid-peptic disease. Similar assessments in patients with documented acid-related disorders are lacki

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cbfdca6a15d84eca58ea5152975c2c8
https://doi.org/10.1038/ajg.2011.220

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Proton Pump Inhibitors: Effective First-Line Treatment for Management of Dyspepsia

Autor: Nancy Y. Siepman, James W. Freston, Betsy L. Pilmer, David A. Peura, Jeff Gudmundson

Publikováno v: Digestive Diseases and Sciences. 52:983-987

The aim of this study was to evaluate the reasons for trial exclusion among dyspeptic patients and estimate the proportion that may have benefited from proton pump inhibitor (PPI) therapy. Stringent inclusion criteria for enrollment in two multicente

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f283c765f590ada8763f977ad3540bb6
https://doi.org/10.1007/s10620-006-9156-7

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Lansoprazole in the treatment of functional dyspepsia: Two Double-Blind, Randomized, Placebo-Controlled trials

Autor: Nancy Y. Siepman, David A. Peura, David C. Metz, Thomas O. Kovacs, Nicholas J. Talley, Betsy L. Pilmer

Publikováno v: The American Journal of Medicine. 116:740-748

The efficacy of proton pump inhibitor therapy for symptom resolution in patients with functional dyspepsia remains controversial. This study was designed to compare the efficacy of lansoprazole with placebo in relieving upper abdominal discomfort in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd18bd4c5c5dc93f26e37ca45bd0f21b
https://doi.org/10.1016/j.amjmed.2004.01.008

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A comparison of simplified lansoprazole suspension administered nasogastrically and pantoprazole administered intravenously: effects on 24-h intragastric pH

Autor: Virender K. Sharma, W. J. Pan, Y. L. Chiu, Betsy L. Pilmer, J. J. Täubel, N. L. Lukasik

Publikováno v: Alimentary Pharmacology & Therapeutics. 15:1807-1817

Aim: To compare the 24-h intragastric pH effects of simplified lansoprazole suspension, 30 mg, administered nasogastrically, with pantoprazole, 40 mg, administered intravenously. Methods: Thirty-six healthy adults were enrolled and given simplified l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::22e599c2434202bfab8488bfcc8537b0
https://doi.org/10.1046/j.1365-2036.2001.01098.x

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The effect of dexlansoprazole MR on nocturnal heartburn and GERD-related sleep disturbances in patients with symptomatic GERD

Autor: Kathleen Stern, M. Claudia Perez, Reema Mody, Cong Han, Betsy L. Pilmer, Ronnie Fass, William C. Orr, David A. Johnson

Publikováno v: The American journal of gastroenterology. 106(3)

Nocturnal heartburn and related sleep disturbances are common among patients with gastroesophageal reflux disease (GERD). This study evaluated the efficacy of dexlansoprazole MR 30 mg in relieving nocturnal heartburn and GERD-related sleep disturbanc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fef401fd1c04a09d5284aa568fcec9f
https://pubmed.ncbi.nlm.nih.gov/21224838

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Comparison of the effects of single and repeated oral doses of lansoprazole and rabeprazole on ambulatory 24-hour intragastric pH in healthy volunteers

Autor: Wei-Jian Pan, Jörg Täubel, Keith G. Tolman, Betsy L. Pilmer, Yi-Lin Chiu, Steven Warrington

Publikováno v: Clinical drug investigation. 26(1)

Background: As the comparative pharmacokinetics and pharmacodynamics of lansoprazole and rabeprazole have not previously been studied, we set out in this study to compare the pharmacokinetics and pharmacodynamics of single and repeated daily doses of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6da4c808df494de912c14000f4549bf8
https://pubmed.ncbi.nlm.nih.gov/17163231

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Bioavailability of lansoprazole granules administered in juice or soft food compared with the intact capsule formulation

Autor: Yi-Lin Chiu, John H. Cavanaugh, Betsy L. Pilmer, Alexander H.C. Chun, Ramanuj Achari, Keith Erdman

Publikováno v: Clinical therapeutics. 24(8)

Background: The ability to administer the contents of an encapsulated-dose formulation in liquids or soft foods without compromising drug bioavailability is highly desirable for patients who are unable to swallow or have difficulty swallowing. Object

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ee50ce92eaf44ed097a921ecaf1a2fe
https://pubmed.ncbi.nlm.nih.gov/12240782

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