Zobrazeno 1 - 10
of 177
pro vyhledávání: '"Betsy J. Barnes"'
Autor:
Bailey K. Roberts, Dan Iris Li, Carter Somerville, Bharati Matta, Vaishali Jha, Adison Steinke, Zarina Brune, Lionel Blanc, Samuel Z. Soffer, Betsy J. Barnes
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Metastasis is driven by extensive cooperation between a tumor and its microenvironment, resulting in the adaptation of molecular mechanisms that evade the immune system and enable pre-metastatic niche (PMN) formation. Little is known of the
Externí odkaz:
https://doaj.org/article/e814d3e28b7740d3bd10af83711e9bac
Autor:
Liseth Carmona-Pérez, Xavier Dagenais-Lussier, Linh T. Mai, Tanja Stögerer, Sharada Swaminathan, Stéphane Isnard, Matthew R. Rice, Betsy J. Barnes, Jean-Pierre Routy, Julien van Grevenynghe, Simona Stäger
Publikováno v:
JCI Insight, Vol 8, Iss 13 (2023)
HIV-1 infection is characterized by inflammation and a progressive decline in CD4+ T cell count. Despite treatment with antiretroviral therapy (ART), the majority of people living with HIV (PLWH) maintain residual levels of inflammation, a low degree
Externí odkaz:
https://doaj.org/article/f2823c61a0e14a9e9f33b2d74c271aa6
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Neutrophil extracellular traps (NETs) are web-like structures extruded by neutrophils after activation or in response to microorganisms. These extracellular structures are decondensed chromatin fibers loaded with antimicrobial granular proteins, pept
Externí odkaz:
https://doaj.org/article/4a6bc49be0ed4b4d85e0b7c363513bc5
Publikováno v:
Molecular Medicine, Vol 26, Iss 1, Pp 1-7 (2020)
Abstract Background Mechanically ventilated patients with COVID-19 have a mortality of 24–53%, in part due to distal mucopurulent secretions interfering with ventilation. DNA from neutrophil extracellular traps (NETs) contribute to the viscosity of
Externí odkaz:
https://doaj.org/article/ea3656d9d7df4a9fa2ca0e4e0b30b0f1
Autor:
Alison E. Obr, Sushil Kumar, Yun-Juan Chang, Joseph J. Bulatowicz, Betsy J. Barnes, Raymond B. Birge, Deborah A. Lazzarino, Emily Gallagher, Derek LeRoith, Teresa L. Wood
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-17 (2018)
Abstract Background Early analyses of human breast cancer identified high expression of the insulin-like growth factor type 1 receptor (IGF-1R) correlated with hormone receptor positive breast cancer and associated with a favorable prognosis, whereas
Externí odkaz:
https://doaj.org/article/7527002bf9444f9290465c96b376aa31
Autor:
Fahmida Rasha, Brianyell McDaniel Mims, Isabel Castro-Piedras, Betsy J. Barnes, Matthew B. Grisham, Rakhshanda Layeequr Rahman, Kevin Pruitt
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Sirtuins belong to the class III family of NAD-dependent histone deacetylases (HDAC) and are involved in diverse physiological processes that range from regulation of metabolism and endocrine function to coordination of immunity and cellular response
Externí odkaz:
https://doaj.org/article/a472100d04ae4e7f90941ba44a643eaa
Autor:
Matthew D. Taylor, Mariana R. Brewer, Ana Nedeljkovic-Kurepa, Yihe Yang, Kalpana S. Reddy, Mabel N. Abraham, Betsy J. Barnes, Clifford S. Deutschman
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Recent studies have demonstrated that induction of a diverse repertoire of memory T cells (“immune education”) affects responses to murine cecal ligation and puncture (CLP), the most widely – used animal model of sepsis. Among the documented ef
Externí odkaz:
https://doaj.org/article/01fef903f6ee4326b247f7f292b2aad9
Publikováno v:
Cell Reports, Vol 31, Iss 13, Pp 107820- (2020)
Summary: IRF5 polymorphisms are associated with multiple immune-mediated diseases, including ulcerative colitis. IRF5 contributions are attributed to its role in myeloid lineages. How T cell-intrinsic IRF5 contributes to inflammatory outcomes is not
Externí odkaz:
https://doaj.org/article/02225abc7f91479c8ec6b9ea38af7d19
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Interferon Regulatory Factor 5 (IRF5) is one of nine members of the IRF family of transcription factors. Although initially discovered as a key regulator of the type I interferon and pro-inflammatory cytokine arm of the innate immune response, IRF5 h
Externí odkaz:
https://doaj.org/article/aeba889a33274fe2bc21c7eaffd3b506
Autor:
Betsy J. Barnes, Carter C. Somerville
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Cytokines are soluble factors that play vital roles in systemic function due to their ability to initiate and mediate cell-to-cell communication. Another important mechanism of intercellular communication that has gained significant attention in the
Externí odkaz:
https://doaj.org/article/110430dbcf1c48b9906c8ffdb257fed4