Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Betsy Hirsch"'
Autor:
Eline J.M. Bertrums, Jenny L. Smith, Lauren Harmon, Rhonda E. Ries, Yi-Cheng J. Wang, Todd A. Alonzo, Andrew J. Menssen, Karen M. Chisholm, Amanda R. Leonti, Katherine Tarlock, Fabiana Ostronoff, Era L. Pogosova-Agadjanyan, Gertjan J.L. Kaspers, Henrik Hasle, Michael Dworzak, Christiane Walter, Nora Muhlegger, Cristina Morerio, Laura Pardo, Betsy Hirsch, Susana Raimondi, Todd M. Cooper, Richard Aplenc, Alan S. Gamis, Edward A. Kolb, Jason E. Farrar, Derek Stirewalt, Xiaotu Ma, Tim I. Shaw, Scott N. Furlan, Lisa Eidenschink Brodersen, Michael R. Loken, Marry M. van den Heuvel-Eibrink, C. Michel Zwaan, Timothy J. Triche, Bianca F. Goemans, Soheil Meshinchi
Publikováno v:
Haematologica, Vol 108, Iss 8 (2023)
NUP98 fusions comprise a family of rare recurrent alterations in AML, associated with adverse outcomes. In order to define the underlying biology and clinical implications of this family of fusions, we performed comprehensive transcriptome, epigenome
Externí odkaz:
https://doaj.org/article/831b66d955b24822ab485927eae2ccd2
Autor:
Richard Aplenc, Soheil Meshinchi, Lillian Sung, Todd Alonzo, John Choi, Brian Fisher, Robert Gerbing, Betsy Hirsch, Terzah Horton, Samir Kahwash, John Levine, Michael Loken, Lisa Brodersen, Jessica Pollard, Susana Raimondi, Edward Anders Kolb, Alan Gamis
Publikováno v:
Haematologica, Vol 105, Iss 7 (2020)
New therapeutic strategies are needed for pediatric acute myeloid leukemia (AML) to reduce disease recurrence and treatment-related morbidity. The Children’s Oncology Group Phase III AAML1031 trial tested whether the addition of bortezomib to stand
Externí odkaz:
https://doaj.org/article/1923b3bd287f4e0aa61b66541e8b65bc
Autor:
Jatinder K. Lamba, Soheil Meshinchi, Alan Gamis, Raul C. Ribeiro, Jeffrey E. Rubnitz, Xueyuan Cao, Stanley Pounds, Janet Franklin, Susana Raimondi, Betsy Hirsch, Michael R. Loken, Jessica A. Pollard, Amit K. Mitra, Robert B. Gerbing, Roland B. Walter, Todd A. Alonzo, Leslie Mortland
Supplementary Table 2. Characteristics of pediatric AML patients treated on St. Jude AML02 trial.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eb316bad638afbd2f6678728480de35
https://doi.org/10.1158/1078-0432.22452522.v1
https://doi.org/10.1158/1078-0432.22452522.v1
Autor:
Jessica A. Pollard, Soheil Meshinchi, Alan S. Gamis, Irwin Bernstein, Richard Aplenc, Lillian Sung, Betsy Hirsch, Susana C. Raimondi, Leela Sarukkai, Jason Joaquin, Tiffany Hylkema, Laura Pardo, Michael R. Loken, Rhonda Ries, Robert B. Gerbing, Yi-Cheng Wang, Todd A. Alonzo, Katherine Tarlock
Supplementary Table 5. Outcome for KIT E8+ mutation positive patients according to treatment arm (No GO vs. GO)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3966b178badc4203ce66d03090b9e5e9
https://doi.org/10.1158/1078-0432.22473624
https://doi.org/10.1158/1078-0432.22473624
Autor:
Jessica A. Pollard, Soheil Meshinchi, Alan S. Gamis, Irwin Bernstein, Richard Aplenc, Lillian Sung, Betsy Hirsch, Susana C. Raimondi, Leela Sarukkai, Jason Joaquin, Tiffany Hylkema, Laura Pardo, Michael R. Loken, Rhonda Ries, Robert B. Gerbing, Yi-Cheng Wang, Todd A. Alonzo, Katherine Tarlock
Purpose:KIT mutations (KIT+) are common in core binding factor (CBF) AML and have been associated with varying prognostic significance. We sought to define the functional and clinical significance of distinct KIT mutations in CBF pediatric AML.Experi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9860ab06204f027f3d41754b27b9e08e
https://doi.org/10.1158/1078-0432.c.6528567
https://doi.org/10.1158/1078-0432.c.6528567
Autor:
Jatinder K. Lamba, Soheil Meshinchi, Alan Gamis, Raul C. Ribeiro, Jeffrey E. Rubnitz, Xueyuan Cao, Stanley Pounds, Janet Franklin, Susana Raimondi, Betsy Hirsch, Michael R. Loken, Jessica A. Pollard, Amit K. Mitra, Robert B. Gerbing, Roland B. Walter, Todd A. Alonzo, Leslie Mortland
Supplementary Table 1. Characteristics of pediatric AML patients treated on AAML03P1 trial by four CD33 SNPs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc4b90ee960f223e00969281f6eca97a
https://doi.org/10.1158/1078-0432.22452525
https://doi.org/10.1158/1078-0432.22452525
Autor:
Jessica A. Pollard, Soheil Meshinchi, Alan S. Gamis, Irwin Bernstein, Richard Aplenc, Lillian Sung, Betsy Hirsch, Susana C. Raimondi, Leela Sarukkai, Jason Joaquin, Tiffany Hylkema, Laura Pardo, Michael R. Loken, Rhonda Ries, Robert B. Gerbing, Yi-Cheng Wang, Todd A. Alonzo, Katherine Tarlock
Supplemental Figure 2. Functional Evaluation and TKI response of E11 mutations. (A) Evaluation of the phosphorylation status of KIT following transfection of the mutations in exon 11, V559D and L576P, into HEK293 cell line. (B) IL-3 independent growt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82b46e0a5b8e40db5a951794f95fcdfc
https://doi.org/10.1158/1078-0432.22473642.v1
https://doi.org/10.1158/1078-0432.22473642.v1
Autor:
Jatinder K. Lamba, Soheil Meshinchi, Alan Gamis, Raul C. Ribeiro, Jeffrey E. Rubnitz, Xueyuan Cao, Stanley Pounds, Janet Franklin, Susana Raimondi, Betsy Hirsch, Michael R. Loken, Jessica A. Pollard, Amit K. Mitra, Robert B. Gerbing, Roland B. Walter, Todd A. Alonzo, Leslie Mortland
Purpose: The purpose of this study was to evaluate clinical implications of CD33 single-nucleotide polymorphisms (SNP) in pediatric patients with acute myeloid leukemia (AML) treated with gemtuzumab-ozogamicin (GO)–based therapy.Experimental Design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3acb29442155e1f2616f7003b8126451
https://doi.org/10.1158/1078-0432.c.6522501.v1
https://doi.org/10.1158/1078-0432.c.6522501.v1
Autor:
Sean I. Tracy, Qing Cao, Ben Bachan, Matthew Meredith, LeAnn Oseth, Daniel Weisdorf, Claudio Brunstein, Betsy Hirsch, Veronika Bachanova
Publikováno v:
European journal of haematology. 109(4)
4. Integrated genetic risk assessment in De-novo Acute Myeloid Leukemia in children and young adults
Autor:
Betsy Hirsch, Todd Cooper, Jessica Pollard, Todd Alonzo, Soheil Meschinchi, Wendy Lee, Matthew Kutny, E. Anders Kolb, Gordana Raca
Publikováno v:
Cancer Genetics. :2