Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Betsy Daugherty"'
Autor:
Betsy Daugherty, Caroline Bishop, Chen Dong, Yongliang Zhang, Paige Holst, Ning Sun, Fred D. Lott, Yeonseok Chung, Andrew A. Welcher, Carole Kurahara, Hilary T. Chute
Publikováno v:
Proceedings of the National Academy of Sciences. 103:11695-11700
T cell activation and tolerance are regulated by costimulatory molecules. Although PD-1 serves as a crucial negative regulator of T cells, the function of its ligands, PDL1 and PDL2, is still controversial. In this study, we created a PDL2-deficient
Autor:
Paul J. Kostenuik, Michael S. Ominsky, Ildiko Sarosi, Jin Cao, Yongming Gao, Mauricio Barrero, Carole Kurahara, Betsy Daugherty, Chris Paszty, Kelly S Warmington, Xiaodong Li, Hua Zhu Ke, Sean Morony, Jianhua Gong, W. Scott Simonet, Ning Sun, Frank Asuncion, Diane D'Agostin, Denise Dwyer, Qing-Tian Niu, Marina Stolina, David L. Lacey
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 23(6)
Introduction: Sclerosteosis is a rare high bone mass genetic disorder in humans caused by inactivating mutations in SOST, the gene encoding sclerostin. Based on these data, sclerostin has emerged as a key negative regulator of bone mass. We generated