Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Betsy Clair"'
Autor:
Abdullah Kutlar, Pritam Bora, Abhishek A. Mangaonkar, Leigh Wells, Latanya Bowman, Niren Patel, Nadine Barrett, James Son, Fahim Thawer, Grace Jung, Hongyan Xu, Germame Ajebo, Betsy Clair, Elizabeta Nemeth
Publikováno v:
British Journal of Haematology. 189:1204-1209
Sickle cell disease (SCD) has a distinct pattern of transfusional iron overload (IO) when compared to transfusion-dependent β-thalassaemia major (TDT). We conducted a single institution prospective study to evaluate plasma biomarkers of iron regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e1f966ade02af2b14a1a42d21803fdb
https://doi.org/10.1111/bjh.16498
https://doi.org/10.1111/bjh.16498
Autor:
Tohru Ikuta, Nadine Odo, Abdullah Kutlar, Diana Gutsaeva, C. Alvin Head, James B. Parkerson, Adekunle Adekile, Betsy Clair, Shobha Yerigenahally
Publikováno v:
Blood Cells, Molecules, and Diseases. 47:235-242
Although reduction in leukocyte counts following hydroxyurea therapy in sickle cell disease (SCD) predicts fetal hemoglobin (HbF) response, the underlying mechanism remains unknown. We previously reported that leukocyte counts are regulated by granul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8548dd9b9193609807584f34c17429ea
https://doi.org/10.1016/j.bcmd.2011.08.005
https://doi.org/10.1016/j.bcmd.2011.08.005
Autor:
Jeanette Harbin, Ferdane Kutlar, Abdullah Kutlar, Dedrey Elam, Betsy Clair, Amy E. Vinson, Michele L. Glendenning, Aisha L. Walker
Publikováno v:
Hemoglobin. 28:317-323
beta-Globin gene cluster haplotypes were originally determined by restriction endonuclease mapping with Southern blots of polymorphic sites around the gene cluster. Over the years, haplotyping has been found to be useful, not only in population genet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b45e16608de6d6454a0f620ebd358329
https://doi.org/10.1081/hem-200037724
https://doi.org/10.1081/hem-200037724
Autor:
Leigh Wells, Leslie Holley, Erin Dainer, Adekunle Adekile, Betsy Clair, Lisa Daitch, Sule M. Bakanay, David M. Smith, Abdullah Kutlar
Publikováno v:
Blood. 105:545-547
The efficacy of hydroxyurea (HU) and its role in the reduction in mortality in sickle cell patients has been established. Nevertheless, many patients still die of complications of this disease while on HU. Of the 226 patients treated with HU at our c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82d432d0d0b9d49c70737dc46b6fbe25
https://doi.org/10.1182/blood-2004-01-0322
https://doi.org/10.1182/blood-2004-01-0322
Autor:
Abdullah Kutlar, Celalettin Ustun, Sabine Fields, Karthi Subbannan, Lisa Daitch, Betsy Clair, Ferdane Kutlar, Kavita Natarajan
Publikováno v:
European journal of haematology. 83(3)
Splenectomy indications and outcome were evaluated in 124 adults with hemoglobin SC disease (Hb SC). Twelve patients (9.6%) required splenectomy. There was a significant difference between the splenectomy group and the non-splenectomy group, respecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b68aedfb2b75952d485445d2041de9e
https://pubmed.ncbi.nlm.nih.gov/19459924
https://pubmed.ncbi.nlm.nih.gov/19459924
Autor:
Dedrey Elam, Leslie Holley, Abdullah Kutlar, A. Addington, Ferdane Kutlar, Adekunle Adekile, Betsy Clair, K. McKie
Publikováno v:
European journal of haematology. 75(2)
PURPOSE Homozygosity for the (AT)7 allele of uridine diphosphate glucuronosyl transferase 1A (UGT1A1) gene polymorphism is associated with increased bilirubin levels in sickle cell anemia (SCA). In the present study, in addition to UGT1A1 promoter ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2984bdfe6575ebfd1aea036f961fbc94
https://pubmed.ncbi.nlm.nih.gov/16004608
https://pubmed.ncbi.nlm.nih.gov/16004608
Autor:
Amy E, Vinson, Aisha, Walker, Dedrey, Elam, Michele, Glendenning, Ferdane, Kutlar, Betsy, Clair, Jeanette, Harbin, Abdullah, Kutlar
Publikováno v:
Hemoglobin. 28(4)
beta-Globin gene cluster haplotypes were originally determined by restriction endonuclease mapping with Southern blots of polymorphic sites around the gene cluster. Over the years, haplotyping has been found to be useful, not only in population genet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::84c4b44b0246486440437230d81c9cdf
https://pubmed.ncbi.nlm.nih.gov/15658187
https://pubmed.ncbi.nlm.nih.gov/15658187
Autor:
Ferdane Kutlar, Gaye T Adams, Robert J. Adams, Donald Brambilla, Harold Snieder, Abdullah Kutlar, Betsy Clair, Virgil McKie
Publikováno v:
BMC Medical Genetics
BMC Medical Genetics, Vol 4, Iss 1, p 6 (2003)
BMC Medical Genetics, Vol 4, Iss 1, p 6 (2003)
Background The phenotypic heterogeneity of sickle cell disease is likely the result of multiple genetic factors and their interaction with the sickle mutation. High transcranial doppler (TCD) velocities define a subgroup of children with sickle cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ab59fb6e3eccea875ad23000c4f74ff
https://pubmed.ncbi.nlm.nih.gov/12871600
https://pubmed.ncbi.nlm.nih.gov/12871600
Autor:
Kavita Natrajan, Cindy E. Neunert, Hongyan Xu, Leigh Wells, Leila Jerome Clay, Arati Rani Chand, Betsy Clair, Abdullah Kutlar, Alison Spellman
Publikováno v:
Blood. 124:4073-4073
Hydroxyurea (HU) is the only FDA approved anti-switching agent for the management of sickle cell disease (SCD). The non-response rate to HU (inadequate increase in fetal hemoglobin (HbF)) has been reported to be as high as 30%. However, the role of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fda57068440b25f6ef2e9bb743ca147
https://doi.org/10.1182/blood.v124.21.4073.4073
https://doi.org/10.1182/blood.v124.21.4073.4073
Autor:
Richard Lottenberg, James A Sirleaf, Robert W. Gibson, Matthew Lyon, Monisola Modupe, Gregory Steele, Gurinder Doad, Betsy Clair, Abdullah Kutlar, Zerettia K McGriff, Robert Krywicki, Witemba Kabange
Publikováno v:
Blood. 124:4854-4854
Background: A growing number of adult patients with sickle cell disease (SCD) receive care in a community setting and often lack access to physicians with sickle cell expertise. To address this healthcare disparity we are testing a co-management medi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::055bad950f3f1bc832fe42b0554271a7
https://doi.org/10.1182/blood.v124.21.4854.4854
https://doi.org/10.1182/blood.v124.21.4854.4854