Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Bethzaida Yarbrough"'
Autor:
David H. Ellison, Bethzaida Yarbrough, Kayla J. Erspamer, Rebecca A. Lazelle, Chao Ling Yang, Mohammed Z. Ferdaus, James A. McCormick, Nicholas P. Meermeier, Andrew S. Terker, Hae J. Park
Publikováno v:
Journal of the American Society of Nephrology. 27:2436-2445
Excess aldosterone is an important contributor to hypertension and cardiovascular disease. Conversely, low circulating aldosterone causes salt wasting and hypotension. Aldosterone activates mineralocorticoid receptors (MRs) to increase epithelial sod
Autor:
Sebastian Bachmann, Nicholas P. Meermeier, Jeffrey D. Singer, Markus Bleich, Brittney Davidge, Eduardo R. Argaiz, Hae J. Park, Katharina I. Blankenstein, Aljona Borschewski, Chao Ling Yang, Gerardo Gamba, Belinda H. McCully, David H. Ellison, Mark West, Chong Zhang, Andrew S. Terker, Nina Himmerkus, Bethzaida Yarbrough, Kerim Mutig, James A. McCormick
Familial hyperkalemic hypertension (FHHt) is a monogenic disease resulting from mutations in genes encoding WNK kinases, the ubiquitin scaffold protein cullin 3 (CUL3), or the substrate adaptor kelch-like 3 (KLHL3). Disease-associated CUL3 mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e90c7e5a6d2532d0ff3fcd09c36f482
https://europepmc.org/articles/PMC4347254/
https://europepmc.org/articles/PMC4347254/
Autor:
David H. Ellison, Nicholas P. Meermeier, Hae Park, Andrew S. Terker, Bethzaida Yarbrough, Jeffrey D. Singer, Belinda H. McCully, James A. McCormick, Chao-Ling Yang
Publikováno v:
The FASEB Journal. 28
Familial Hyperkalemic Hypertension (FHHt) is caused by mutations in genes that regulate activity of the renal sodium chloride cotransporter (NCC), including the kinases WNK1 and WNK4, and Cullin3 (Cul3) and KLHL3, members of a ring ubiquitin ligase c