Ramucirumab plus paclitaxel as switch maintenance versus continuation of first-line oxaliplatin-based chemotherapy in patients with advanced HER2-negative gastric or gastro-oesophageal junction cancer (ARMANI): a randomised, open-label, multicentre, phase 3 trial.

Autor: Randon G; Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Lonardi S; Department of Oncology, Veneto Institute of Oncology Istituto Oncologico Veneto-IRCCS, Padua, Italy., Fassan M; Surgical Pathology Unit, Department of Medicine, University Hospital of Padua, Padua, Italy; Veneto Institute of Oncology IOV-IRCCS, Padua, Italy., Palermo F; Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Tamberi S; Oncology Unit, Santa Maria delle Croci Hospital, Azienda Unità Sanitaria Locale della Romagna, Ravenna, Italy., Giommoni E; Medical Oncology Unit, Careggi University Hospital, Florence, Italy., Ceccon C; Surgical Pathology Unit, Department of Medicine, University Hospital of Padua, Padua, Italy., Di Donato S; Medical Oncology Department ASL Toscana Centro, Santo Stefano Hospital, Prato, Italy., Fornaro L; Unit of Medical Oncology, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy., Brunetti O; Istituto Tumori 'Giovanni Paolo II' of Bari IRCCS, Bari, Italy., De Vita F; Division of Medical Oncology, Department of Precision Medicine, University of Campania 'L Vanvitelli', Naples, Italy., Bittoni A; Oncology Unit, Istituto Romagnolo Per Lo Studio Dei Tumori 'Dino Amadori' IRCCS, Meldola, Italy., Chini C; Department of Medical Oncology, ASST Sette Laghi, Ospedale di Circolo e Fondazione Macchi, Varese, Italy., Spallanzani A; Department of Oncology and Haematology, Division of Oncology, University Hospital of Modena, Modena, Italy., Nappo F; Department of Oncology, Veneto Institute of Oncology Istituto Oncologico Veneto-IRCCS, Padua, Italy., Bethaz V; Department of Oncology, 'San Luigi Gonzaga' University Hospital, University of Turin, Orbassano, Italy., Strippoli A; Comprehensive Cancer Center, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy., Latiano T; Department of Oncology, Fondazione IRCCS 'Casa Sollievo della Sofferenza' Hospital, San Giovanni Rotondo, Foggia, Italy., Cardellino GG; Department of Oncology, Azienda Sanitaria Universitaria Friuli Centrale, Udine, Italy., Giuliani F; Istituto Tumori 'Giovanni Paolo II' of Bari IRCCS, Bari, Italy; Medical Oncology Unit, San Paolo Hospital, Bari, Italy., Morano F; Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Niger M; Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Raimondi A; Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Prisciandaro M; Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Pircher CC; Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Sciortino C; Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Marchesi S; Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Garattini SK; Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy; Department of Oncology, Azienda Sanitaria Universitaria Friuli Centrale, Udine, Italy., Airò G; Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy; Department of Medicine and Surgery, University of Parma, Parma, Italy., Miceli R; Unit of Biostatistics for Clinical Research, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Di Bartolomeo M; Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Pietrantonio F; Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. Electronic address: filippo.pietrantonio@istitutotumori.mi.it.

Publikováno v: The Lancet. Oncology [Lancet Oncol] 2024 Nov 15. Date of Electronic Publication: 2024 Nov 15.