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pro vyhledávání: '"Bethany Rebekah Hill"'
Autor:
Bethany Rebekah Hill, Meryem Ozgencil, Lauryn Buckley-Benbow, Sophie Louise Pamela Skingsley, Danielle Tomlinson, Carmen Ortueta Eizmendi, Alessandro Agnarelli, Roberto Bellelli
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114205- (2024)
Summary: The advent of PARP inhibitors (PARPis) has profoundly changed the treatment landscape of BRCA1/BRCA2-mutated cancers. Despite this, the development of resistance to these compounds has become a major challenge. Hence, a detailed understandin
Externí odkaz:
https://doaj.org/article/b0655d227f064be5b18ff8cfe8c50489
Autor:
Valerie Borel, Stefan Boeing, Niek Van Wietmarschen, Sriram Sridharan, Bethany Rebekah Hill, Luigi Ombrato, Jimena Perez-Lloret, Deb Jackson, Robert Goldstone, Simon J. Boulton, Andre Nussenzweig, Roberto Bellelli
The maintenance of genome stability relies on coordinated control of origin activation and replication fork progression. How the interplay between these processes influences human genetic disease and cancer remains incompletely characterized. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05cd3dfe1365b41e1240ae5517cf093a
