Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Bethany P. Cummings"'
Autor:
Melanie A. Reuter, Madelynn Tucker, Zara Marfori, Rahaf Shishani, Jessica Miranda Bustamante, Rosalinda Moreno, Michael L. Goodson, Allison Ehrlich, Ameer Y. Taha, Pamela J. Lein, Nikhil Joshi, Ilana Brito, Blythe Durbin-Johnson, Renu Nandakumar, Bethany P. Cummings
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
ABSTRACTBile acids (BA) are among the most abundant metabolites produced by the gut microbiome. Primary BAs produced in the liver are converted by gut bacterial 7-α-dehydroxylation into secondary BAs, which can differentially regulate host health vi
Externí odkaz:
https://doaj.org/article/a2e0617ddb494a5099979126d2fc15aa
Autor:
Journey L. Wise, Bethany P. Cummings
Publikováno v:
Frontiers in Microbiology, Vol 13 (2023)
The gut microbiome plays a significant role in maintaining host metabolic health through the production of metabolites. Comprising one of the most abundant and diverse forms of gut metabolites, bile acids play a key role in blood glucose regulation,
Externí odkaz:
https://doaj.org/article/50774c72767947c29333b9ae61ed2b1f
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
As an incretin hormone, glucagon-like peptide 1 (GLP-1) lowers blood glucose levels by enhancing glucose-stimulated insulin secretion from pancreatic beta-cells. Therapies targeting the GLP-1 receptor (GLP-1R) use the classical incretin model as a ph
Externí odkaz:
https://doaj.org/article/2cd53a8838c742bdbd5a056e2f5d1475
Autor:
Jennifer M. Noto, M. Blanca Piazuelo, Shailja C. Shah, Judith Romero-Gallo, Jessica L. Hart, Chao Di, James D. Carmichael, Alberto G. Delgado, Alese E. Halvorson, Robert A. Greevy, Lydia E. Wroblewski, Ayushi Sharma, Annabelle B. Newton, Margaret M. Allaman, Keith T. Wilson, M. Kay Washington, M. Wade Calcutt, Kevin L. Schey, Bethany P. Cummings, Charles R. Flynn, Joseph P. Zackular, Richard M. Peek Jr.
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 10 (2022)
Gastric carcinogenesis is mediated by complex interactions among Helicobacter pylori, host, and environmental factors. Here, we demonstrate that H. pylori augmented gastric injury in INS-GAS mice under iron-deficient conditions. Mechanistically, thes
Externí odkaz:
https://doaj.org/article/7d198f5f9fa7400583ab84388b9c0680
Autor:
Mridusmita Saikia, Marlena M. Holter, Leanne R. Donahue, Isaac S. Lee, Qiaonan C. Zheng, Journey L. Wise, Jenna E. Todero, Daryl J. Phuong, Darline Garibay, Reilly Coch, Kyle W. Sloop, Adolfo Garcia-Ocana, Charles G. Danko, Bethany P. Cummings
Publikováno v:
JCI Insight, Vol 6, Iss 3 (2021)
Glucagon-like peptide-1 (GLP-1) is an incretin hormone that potentiates glucose-stimulated insulin secretion. GLP-1 is classically produced by gut L cells; however, under certain circumstances α cells can express the prohormone convertase required f
Externí odkaz:
https://doaj.org/article/d8231da5c1ae478aaa15444e8576fb6f
Autor:
Darline Garibay, Jon Lou, Seon A. Lee, Karolina E. Zaborska, Margot H. Weissman, Erica Sloma, Leanne Donahue, Andrew D. Miller, Andrew C. White, M. Dodson Michael, Kyle W. Sloop, Bethany P. Cummings
Publikováno v:
Cell Reports, Vol 23, Iss 4, Pp 967-973 (2018)
Summary: Bariatric surgery, such as vertical sleeve gastrectomy (VSG), causes high rates of type 2 diabetes remission and remarkable increases in postprandial glucagon-like peptide-1 (GLP-1) secretion. GLP-1 plays a critical role in islet function by
Externí odkaz:
https://doaj.org/article/940bc9769f4046a8a710f3ef5f3a7948
Autor:
Anne K. McGavigan, Zachariah M. Henseler, Darline Garibay, Scott D. Butler, Sisitha Jayasinghe, Ruth E. Ley, Robin L. Davisson, Bethany P. Cummings
Publikováno v:
Disease Models & Mechanisms, Vol 10, Iss 3, Pp 235-243 (2017)
Bariatric surgery, such as vertical sleeve gastrectomy (VSG), causes remarkable improvements in cardiometabolic health, including hypertension remission. However, the mechanisms responsible remain undefined and poorly studied. Therefore, we developed
Externí odkaz:
https://doaj.org/article/481678142d494caeac5fa493991c6bc7
Autor:
Brandon J. Gheller, Jamie E. Blum, Edward K. Merritt, Bethany P. Cummings, Anna E. Thalacker-Mercer
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Peptide YY (PYY) is considered a gut peptide with roles in post-prandial appetite and glucose regulation. Circulating PYY protein levels increase during aerobic exercise. Furthermore, people who have greater increases in muscle progenitor cells (hMPC
Externí odkaz:
https://doaj.org/article/d3f5da729ad24c7bbf000ab76f6c766c
Autor:
Bethany P. Cummings, Ahmed Bettaieb, James L. Graham, Jaehyoung Kim, Fangrui Ma, Noreene Shibata, Kimber L. Stanhope, Cecilia Giulivi, Frederik Hansen, Jacob Jelsing, Niels Vrang, Mark Kowala, Michael L. Chouinard, Fawaz G. Haj, Peter J. Havel
Publikováno v:
Disease Models & Mechanisms, Vol 6, Iss 2, Pp 443-456 (2013)
SUMMARY Post-operative increases in circulating bile acids have been suggested to contribute to the metabolic benefits of bariatric surgery; however, their mechanistic contributions remain undefined. We have previously reported that ileal interpositi
Externí odkaz:
https://doaj.org/article/169c56b101764eb88ac96ae43bc855c5
Publikováno v:
American Journal of Veterinary Research. :1-8
OBJECTIVE To compare plasma concentrations of glucagon and glucagon-like peptide-1 (GLP-1) between healthy dogs and dogs with aminoaciduric canine hypoaminoacidemic hepatopathy syndrome (ACHES) dogs. ANIMALS Privately owned healthy (n = 5) control (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de933d5b0214ed3fb1572451cd19f174
https://doi.org/10.2460/ajvr.22.10.0174
https://doi.org/10.2460/ajvr.22.10.0174