Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Bethany N Smith"'
Autor:
Bethany N Smith, Liza J Burton, Veronica Henderson, Diandra D Randle, Derrick J Morton, Basil A Smith, Latonia Taliaferro-Smith, Peri Nagappan, Clayton Yates, Majd Zayzafoon, Leland W K Chung, Valerie A Odero-Marah
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104987 (2014)
Snail transcription factor is up-regulated in several cancers and associated with increased tumor migration and invasion via induction of epithelial-to-mesenchymal transition (EMT). MAPK (ERK1/2) signaling regulates cellular processes including cell
Externí odkaz:
https://doaj.org/article/d1a6e9c32d6a46d996074e68b30dc4fc
Autor:
Bethany N. Smith, Rajeev Mishra, Sandrine Billet, Veronica R. Placencio-Hickok, Minhyung Kim, Le Zhang, Frank Duong, Anisha Madhav, Kevin Scher, Nancy Moldawer, Amy Oppenheim, Bryan Angara, Sungyong You, Mourad Tighiouart, Edwin M. Posadas, Neil A. Bhowmick
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 31(1)
Androgen receptor signaling inhibitors (ARSIs) are standard of care for advanced prostate cancer (PCa) patients. Eventual resistance to ARSIs can include the expression of androgen receptor (AR) splice variant, AR-V7, expression as a recognized means
Autor:
Liza J. Burton, Jasmine Jones, Bethany N. Smith, Valerie Odero-Marah, Veronica Henderson, Diandra D. Randle, Jodi Dougan
Publikováno v:
Mol Cell Biol
The epithelial mesenchymal transition (EMT) promotes tumor migration and invasion by downregulating epithelial markers such as E-cadherin and upregulating mesenchymal markers such as vimentin. Cathepsin L (Cat L) is a cysteine protease that can prote
Autor:
Bethany N. Smith, Valerie Odero-Marah
Publikováno v:
Cell Adhesion & Migration. 6:433-441
Prostate cancer is the second most frequently diagnosed cancer and the sixth leading cause of death from cancer in men. Epithelial-mesenchymal transition (EMT) is a process by which cancer cells invade and migrate, and is characterized by loss of cel
Autor:
Valerie Odero-Marah, Veronica Henderson, Tisheeka R. Graham, Danielle McKeithen, Corey L. Neal, Bethany N. Smith, BaoHan T. Vo
Publikováno v:
BMC Cancer
BMC Cancer, Vol 12, Iss 1, p 336 (2012)
BMC Cancer, Vol 12, Iss 1, p 336 (2012)
Background Maspin, a putative tumor suppressor that is down-regulated in breast and prostate cancer, has been associated with decreased cell motility. Snail transcription factor is a zinc finger protein that is increased in breast cancer and is assoc
Publikováno v:
Cancer Research. 75:4105-4105
The Epithelial Mesenchymal Transition (EMT) is a key event in tumor migration and invasion processes whereby epithelial cells lose polarity together with cell-cell contacts associated with loss of epithelial markers such as E-cadherin and then underg
Autor:
Peri Nagappan, Bethany N. Smith, Cimona V. Hinton, Roman Mezencev, Clayton Yates, LaTonia Taliaferro-Smith, Valerie Odero-Marah
Publikováno v:
Cancer Research. 74:1131-1131
Snail transcription factor and MAPK/ERK signaling regulate EMT and chemotherapy resistance in various tumor models by binding to target promoters (i.e., E-cadherin, maspin, ER-α). ERK1 is expressed during embryogenesis and in non-metastatic cells; E
Autor:
Valerie Odero-Marah, Cimona V. Hinton, Peri Nagappan, Clayton Yates, Bethany N. Smith, Mahandranauth A. Chetram, LaTonia Taliaferro-Smith
Publikováno v:
Cancer Research. 73:1485-1485
Snail is a zinc finger transcriptional repressor that induces epithelial-mesenchymal transitions (EMT) and is expressed at high levels in tumors. Snail contributes to chemotherapy resistance in ovarian, liver, colorectal, and breast carcinomas by act
Autor:
Valerie Odero-Marah, Bethany N. Smith, Tamar Saintil, LaTonia Taliaferro-Smith, Mahandranauth A. Chetram, Clayton Yates, Peri Nagappan, Cimona V. Hinton
Publikováno v:
Cancer Research. 72:5747-5747
Snail (Snail1) is a zinc finger transcription factor that can induce EMT and is expressed at high levels in tumors. Maspin is a potential tumor suppressor, whose expression is lost as breast and prostate tumors progress during EMT. Maspin can be tran
Autor:
Bethany N. Smith, Neil A. Bhowmick
Publikováno v:
Journal of Clinical Medicine, Vol 5, Iss 2, p 17 (2016)
Epithelial–mesenchymal transition (EMT) is a complex molecular program that regulates changes in cell morphology and function during embryogenesis and tissue development. EMT also contributes to tumor progression and metastasis. Cells undergoing EM
Externí odkaz:
https://doaj.org/article/5f77ee974be441358679758292416115