Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Bethany L. Peterson"'
Autor:
Raymond T. Bartus, Alexandre Bétourné, Anthony Basile, Bethany L. Peterson, Jonathan Glass, Nicholas M. Boulis
Publikováno v:
Neurobiology of Disease, Vol 85, Iss , Pp 11-24 (2016)
Amyotrophic lateral sclerosis (ALS) is a chronic and progressive neuromuscular disease for which no cure exists and better treatment options are desperately needed. We hypothesize that currently approved β2-adrenoceptor agonists may effectively trea
Externí odkaz:
https://doaj.org/article/53c428238159499bacf69212faa14549
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146419 (2016)
PURPOSE:We recently showed that progesterone treatment can reduce lesion size and behavioral deficits after moderate-to-severe bilateral injury to the medial prefrontal cortex in immature male rats. Whether there are important sex differences in resp
Externí odkaz:
https://doaj.org/article/798670f97d6e404b9193c6237b5eb91e
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0122821 (2015)
Maintaining blood-brain barrier integrity and minimizing neuronal injury are critical components of any therapeutic intervention following ischemic stroke. However, a low level of vitamin D hormone is a risk factor for many vascular diseases includin
Externí odkaz:
https://doaj.org/article/75d45eea63a6480683e4ab212ec7e3f4
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31568 (2012)
Naked mole-rats are highly social and strictly subterranean rodents that live in large communal colonies in sealed and chronically oxygen-depleted burrows. Brain slices from naked mole-rats show extreme tolerance to hypoxia compared to slices from ot
Externí odkaz:
https://doaj.org/article/987399ebeca54504b0108386d695d750
Autor:
Ole Eigenbrod, Wiebke Hamann, Richard D. Minshall, Tetiana Kosten, Christin Zasada, Victoria M Gavaghan, Michael Gotthardt, Stefan Kempa, Gary R. Lewin, Bethany L. Peterson, John Larson, Heike Lutermann, Nigel C. Bennett, P. Henning J. L. Kuich, Vince G. Amoroso, Thomas J. Park, Ewan St. John Smith, Daniel T. Applegate, Brigitte M. Browe, Michael H. Radke, Vidya Govind, Jane Reznick, Gregory R.C. Blass, Damir Omerbašić, Valérie Bégay
Safe anaerobic metabolism Naked mole-rats live in large colonies deep underground in hypoxic conditions. Park et al. found that these animals fuel anaerobic glycolysis with fructose by a rewired pathway that avoids tissue damage (see the Perspective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::620802a7ea88d559542ab6f073fb6b24
https://www.repository.cam.ac.uk/handle/1810/264126
https://www.repository.cam.ac.uk/handle/1810/264126
Publikováno v:
Journal of Neuroscience Methods. 216:110-117
A microfluidic oxygenator is used to deliver constant oxygen to rodent brain slices, enabling the loading of the cell-permeant calcium indicator Fura-2/AM into cells of adult brain slices. When compared to traditional methods, our microfluidic oxygen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e7574bd1193715c9ea2e8e5ffdde6b6
https://doi.org/10.1016/j.jneumeth.2013.04.007
https://doi.org/10.1016/j.jneumeth.2013.04.007
Publikováno v:
Neuroscience Letters. 506:342-345
Adult naked mole-rats show a number of systemic adaptations to a crowded underground habitat that is low in oxygen and high in carbon dioxide. Remarkably, brain slice tissue from adult naked mole-rats also is extremely tolerant to oxygen deprivation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63f19b85683a5d2706668afa44d0bcbb
https://doi.org/10.1016/j.neulet.2011.11.042
https://doi.org/10.1016/j.neulet.2011.11.042
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 3, p e0122821 (2015)
PLoS ONE, Vol 10, Iss 3, p e0122821 (2015)
Maintaining blood-brain barrier integrity and minimizing neuronal injury are critical components of any therapeutic intervention following ischemic stroke. However, a low level of vitamin D hormone is a risk factor for many vascular diseases includin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbe08ab46bc1afffe2e5d586ed065376
https://pubmed.ncbi.nlm.nih.gov/25815722
https://pubmed.ncbi.nlm.nih.gov/25815722
Publikováno v:
Behavioural brain research. 286
There is no satisfactory therapeutic intervention for neonatal hypoxic-ischemic (HI) encephalopathy. Progesterone is known to be effective in treating traumatic brain injury in adult animals but its effects in neonatal brains have not been reported.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::232bb75d44dec050425e7d81694a4dfc
https://pubmed.ncbi.nlm.nih.gov/25746450
https://pubmed.ncbi.nlm.nih.gov/25746450
Autor:
Alexandre Betourne, Ray Bartus, Bethany L. Peterson, Thais Federici, Juanmarco Gutierrez, Nicholas M. Boulis
Publikováno v:
Neurosurgery. 63:193
INTRODUCTION:Oral administration of riluzole is the only Food and Drug Administration-approved therapy for amyotrophic lateral sclerosis (ALS). However, per os riluzole therapy has shown modest efficacy and is limited by its negative impact on liver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72ceee2af6d2d1084632a5f07ec5060d
https://doi.org/10.1227/01.neu.0000489810.52605.80
https://doi.org/10.1227/01.neu.0000489810.52605.80