Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Bethany L Dearlove"'
Autor:
Eric Lewitus, Samantha M Townsley, Yifan Li, Gina C Donofrio, Bethany L Dearlove, Hongjun Bai, Eric Sanders-Buell, Anne Marie O'Sullivan, Meera Bose, Hannah Kibuuka, Lucas Maganga, Sorachai Nitayaphan, Fredrick K Sawe, Leigh Anne Eller, Nelson L Michael, Victoria R Polonis, Julie A Ake, Sandhya Vasan, Merlin L Robb, Sodsai Tovanabutra, Shelly J Krebs, Morgane Rolland
Publikováno v:
PLoS Pathogens, Vol 18, Iss 3, p e1010369 (2022)
Eliciting broadly neutralizing antibodies (bnAbs) is a cornerstone of HIV-1 vaccine strategies. Comparing HIV-1 envelope (env) sequences from the first weeks of infection to the breadth of antibody responses observed several years after infection can
Externí odkaz:
https://doaj.org/article/113e99203ef947cfad3ab559159eb9c8
Autor:
Bethany L Dearlove, Simon D W Frost
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 7, p e1004312 (2015)
Previous work has shown that asymmetry in viral phylogenies may be indicative of heterogeneity in transmission, for example due to acute HIV infection or the presence of 'core groups' with higher contact rates. Hence, evidence of asymmetry may provid
Externí odkaz:
https://doaj.org/article/bceafeff459244e78a176a2bf80c6209
Autor:
Craig A. Magaret, Li Li, Allan C. deCamp, Morgane Rolland, Michal Juraska, Brian D. Williamson, James Ludwig, Cindy Molitor, David Benkeser, Alex Luedtke, Brian Simpkins, Fei Heng, Yanqing Sun, Lindsay N. Carpp, Hongjun Bai, Bethany L. Dearlove, Elena E. Giorgi, Mandy Jongeneelen, Boerries Brandenburg, Matthew McCallum, John E. Bowen, David Veesler, Jerald Sadoff, Glenda E. Gray, Sanne Roels, An Vandebosch, Daniel J. Stieh, Mathieu Le Gars, Johan Vingerhoets, Beatriz Grinsztejn, Paul A. Goepfert, Leonardo Paiva de Sousa, Mayara Secco Torres Silva, Martin Casapia, Marcelo H. Losso, Susan J. Little, Aditya Gaur, Linda-Gail Bekker, Nigel Garrett, Carla Truyers, Ilse Van Dromme, Edith Swann, Mary A. Marovich, Dean Follmann, Kathleen M. Neuzil, Lawrence Corey, Alexander L. Greninger, Pavitra Roychoudhury, Ollivier Hyrien, Peter B. Gilbert
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract In the ENSEMBLE randomized, placebo-controlled phase 3 trial (NCT04505722), estimated single-dose Ad26.COV2.S vaccine efficacy (VE) was 56% against moderate to severe–critical COVID-19. SARS-CoV-2 Spike sequences were determined from 484 v
Externí odkaz:
https://doaj.org/article/ae82624b40e944a5925f8f3c70ded9b7
Autor:
Marciela M. DeGrace, Elodie Ghedin, Matthew B. Frieman, Florian Krammer, Alba Grifoni, Arghavan Alisoltani, Galit Alter, Rama R. Amara, Ralph S. Baric, Dan H. Barouch, Jesse D. Bloom, Louis-Marie Bloyet, Gaston Bonenfant, Adrianus C. M. Boon, Eli A. Boritz, Debbie L. Bratt, Traci L. Bricker, Liliana Brown, William J. Buchser, Juan Manuel Carreño, Liel Cohen-Lavi, Tamarand L. Darling, Meredith E. Davis-Gardner, Bethany L. Dearlove, Han Di, Meike Dittmann, Nicole A. Doria-Rose, Daniel C. Douek, Christian Drosten, Venkata-Viswanadh Edara, Ali Ellebedy, Thomas P. Fabrizio, Guido Ferrari, Will M. Fischer, William C. Florence, Ron A. M. Fouchier, John Franks, Adolfo García-Sastre, Adam Godzik, Ana Silvia Gonzalez-Reiche, Aubree Gordon, Bart L. Haagmans, Peter J. Halfmann, David D. Ho, Michael R. Holbrook, Yaoxing Huang, Sarah L. James, Lukasz Jaroszewski, Trushar Jeevan, Robert M. Johnson, Terry C. Jones, Astha Joshi, Yoshihiro Kawaoka, Lisa Kercher, Marion P. G. Koopmans, Bette Korber, Eilay Koren, Richard A. Koup, Eric B. LeGresley, Jacob E. Lemieux, Mariel J. Liebeskind, Zhuoming Liu, Brandi Livingston, James P. Logue, Yang Luo, Adrian B. McDermott, Margaret J. McElrath, Victoria A. Meliopoulos, Vineet D. Menachery, David C. Montefiori, Barbara Mühlemann, Vincent J. Munster, Jenny E. Munt, Manoj S. Nair, Antonia Netzl, Anna M. Niewiadomska, Sijy O’Dell, Andrew Pekosz, Stanley Perlman, Marjorie C. Pontelli, Barry Rockx, Morgane Rolland, Paul W. Rothlauf, Sinai Sacharen, Richard H. Scheuermann, Stephen D. Schmidt, Michael Schotsaert, Stacey Schultz-Cherry, Robert A. Seder, Mayya Sedova, Alessandro Sette, Reed S. Shabman, Xiaoying Shen, Pei-Yong Shi, Maulik Shukla, Viviana Simon, Spencer Stumpf, Nancy J. Sullivan, Larissa B. Thackray, James Theiler, Paul G. Thomas, Sanja Trifkovic, Sina Türeli, Samuel A. Turner, Maria A. Vakaki, Harm van Bakel, Laura A. VanBlargan, Leah R. Vincent, Zachary S. Wallace, Li Wang, Maple Wang, Pengfei Wang, Wei Wang, Scott C. Weaver, Richard J. Webby, Carol D. Weiss, David E. Wentworth, Stuart M. Weston, Sean P. J. Whelan, Bradley M. Whitener, Samuel H. Wilks, Xuping Xie, Baoling Ying, Hyejin Yoon, Bin Zhou, Tomer Hertz, Derek J. Smith, Michael S. Diamond, Diane J. Post, Mehul S. Suthar
Publikováno v:
Nature
The global emergence of many severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants jeopardizes the protective antiviral immunity induced following infection or vaccination. To address the public health threat caused by the increasing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e896e07b5a30bbcb962870bf7aaa91b
https://www.repository.cam.ac.uk/handle/1810/335637
https://www.repository.cam.ac.uk/handle/1810/335637
Autor:
Eric Lewitus, Samantha M. Townsley, Yifan Li, Gina C. Donofrio, Bethany L. Dearlove, Hongjun Bai, Eric Sanders-Buell, Anne Marie O’Sullivan, Meera Bose, Hannah Kibuuka, Lucas Maganga, Sorachai Nitayaphan, Fredrick K. Sawe, Leigh Anne Eller, Nelson L. Michael, Victoria R. Polonis, Julie A. Ake, Sandhya Vasan, Merlin L. Robb, Sodsai Tovanabutra, Shelly J. Krebs, Morgane Rolland
Publikováno v:
PLoS pathogens. 18(3)
Eliciting broadly neutralizing antibodies (bnAbs) is a cornerstone of HIV-1 vaccine strategies. Comparing HIV-1 envelope (env) sequences from the first weeks of infection to the breadth of antibody responses observed several years after infection can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4291d919cc8fa57c4daa01b527d38df0
https://pubmed.ncbi.nlm.nih.gov/35303045
https://pubmed.ncbi.nlm.nih.gov/35303045
Autor:
Nelson L. Michael, Hongjun Bai, Bethany L. Dearlove, Sandhya Vasan, Mihret F. Amare, Eric Lewitus, Kayvon Modjarrad, Daniel B. Reeves, Morgane Rolland, Paul T. Scott, M. Gordon Joyce, Yifan Li
Publikováno v:
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
The magnitude of the COVID-19 pandemic underscores the urgency for a safe and effective vaccine. Many vaccine candidates focus on the Spike protein, as it is targeted by neutralizing antibodies and plays a key role in viral entry. Here we investigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1a324c28282fb07c95b04be903ccf6e
Autor:
Daniel B. Reeves, Joshua T. Schiffer, Yifan Li, Merlin L. Robb, E Fabian Cardozo-Ojeda, Morgane Rolland, Peter B. Gilbert, Bethany L. Dearlove, Bryan T. Mayer
In HIV prevention trials, precise identification of infection time is critical to quantify drug efficacy but difficult to estimate as trials may have relatively sparse visit schedules. The last negative visit does not guarantee a boundary on infectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da78f035b24911ea963017e6b34673c0
https://doi.org/10.1101/2020.08.13.20174243
https://doi.org/10.1101/2020.08.13.20174243
Autor:
Bethany L. Dearlove, Paul T. Scott, Mihret F. Amare, Sandhya Vasan, Eric Lewitus, Hongjun Bai, Daniel B. Reeves, Yifan Li, Kayvon Modjarrad, Nelson L. Michael, M. Gordon Joyce, Morgane Rolland
The magnitude of the COVID-19 pandemic underscores the urgency for a safe and effective vaccine. Here we analyzed SARS-CoV-2 sequence diversity across 5,700 sequences sampled since December 2019. The Spike protein, which is the target immunogen of mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81962d3f3ea972fd1635008d2a337bc0
https://doi.org/10.1101/2020.04.27.064774
https://doi.org/10.1101/2020.04.27.064774
Autor:
Raabya Rossenkhan, Lydia Bonar, Jan P.L. Labuschagne, Meera Bose, Kultida Poltavee, Elizabeth A. Harbolick, Daniel B. Reeves, Morgane Rolland, Jerome H. Kim, Bethany L. Dearlove, Leigh Anne Eller, Merlin L. Robb, Gustavo H. Kijak, Hannah Kibuuka, Paul T. Edlefsen, Eric Lewitus, Phuc Pham, Bahar Ahani, Annemarie O'Sullivan, Shana Miller, Eric Sanders-Buell, Sorachai Nitayaphan, Fred Sawe, Jenica Lee, Christopher L. Owen, Yifan Li, Robert Gramzinski, Lucas Maganga, Nelson L. Michael, Sodsai Tovanabutra
Publikováno v:
PLoS Pathogens, Vol 16, Iss 2, p e1008179 (2020)
PLoS Pathogens
PLoS Pathogens
Most HIV-1 infected individuals do not know their infection dates. Precise infection timing is crucial information for studies that document transmission networks or drug levels at infection. To improve infection timing, we used the prospective RV217
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11231a76c5d47375b0321412c813401d
https://doaj.org/article/4eba0f9f21794581ba1e24b1058d88ef
https://doaj.org/article/4eba0f9f21794581ba1e24b1058d88ef
Autor:
Art F. Y. Poon, Bethany L. Dearlove
Publikováno v:
The Journal of Infectious Diseases. 217:1854-1857
BACKGROUND: Harm reduction has dramatically reduced HIV incidence among people who inject drugs (PWID). In Glasgow, Scotland, 90%) is indicative of sharing of injecting equipment. Monitoring the epidemic phylogenetically in real time may accelerate p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::295c23bf27eef1374af6d85cd36f12f1
https://doi.org/10.1093/infdis/jiy132
https://doi.org/10.1093/infdis/jiy132