Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Bethany E. Beasley"'
Autor:
Barbara K. Goodman, Garnett Kelsoe, Marc C. Levesque, Jon P. Gockerman, John F. Whitesides, Bethany E. Beasley, Joseph O. Moore, Alicia D. Volkheimer, J. Brice Weinberg
Publikováno v:
Blood. 109:1559-1567
Somatic mutations of immunoglobulin genes characterize mature memory B cells, and intraclonal B-cell diversification is typically associated with expansion of B-cell clones with greater affinity for antigen (antigen drive). Evidence for a role of ant
Autor:
Bethany E. Beasley, Youwei Chen, Joseph O. Moore, Charles W. O’Loughlin, J. Brice Weinberg, Jon P. Gockerman, Marc C. Levesque
Publikováno v:
Leukemia Research. 30:24-28
B cell chronic lymphocytic leukemia (CLL) CD38 expression is variable and may predict outcome. Inducible nitric oxide synthase (NOS2) expression regulates CLL cell apoptosis. IL-4 and IFN-gamma regulate B cell CD38 expression and NOS2 expression. We
Autor:
D L Wilson, Youwei Chen, Bethany E. Beasley, R Silber, Charles W. O’Loughlin, Mary A. Misukonis, David J. Adams, JB Weinberg, Marc C. Levesque
Publikováno v:
Leukemia. 17:442-450
Chronic lymphocytic leukemia (B-CLL) is characterized by the accumulation of long-lived non-dividing CD5(+) B cells. Nitric oxide (NO) is an important regulator of apoptosis, and the viability of cultured B-CLL cells may be dependent on the autocrine
Autor:
Ning Jiang, Youwei Chen, J. Brice Weinberg, Dipak K. Ghosh, Bethany E. Beasley, John C. Salerno
Publikováno v:
Free radical biologymedicine. 46(12)
Cobalamins are important cofactors for methionine synthase and methylmalonyl-CoA mutase. Certain corrins also bind nitric oxide (NO), quenching its bioactivity. To determine if corrins would inhibit NO synthase (NOS), we measured their effects on -L-
Autor:
Jon P. Gockerman, Marc C. Levesque, Youwei Chen, Dipak K. Ghosh, J. Brice Weinberg, Bethany E. Beasley, Joseph O. Moore, Charles W. O’Loughlin, Alicia D. Volkheimer
Publikováno v:
Leukemia research. 32(7)
Nitric oxide synthase (NOS) inhibitors induce chronic lymphocytic leukemia (CLL) cell apoptosis and have potential as CLL therapeutics. We determined the half-maximal concentration (ED(50)) of 22 NOS inhibitors that induced CLL cell death in vitro. T
Autor:
Gina Vaccaro, Joseph O. Moore, Ning Jiang, David A. Rizzieri, Mark C. Lanasa, Barbara K. Goodman, Catherine Rehder, Alicia D. Volkheimer, Louis F. Diehl, Carlos M. DeCastro, Bethany E. Beasley, Daphne R. Friedman, Marc C. Levesque, J. Brice Weinberg, Jon P. Gockerman, Youwei Chen
Publikováno v:
American journal of hematology. 82(12)
Several parameters may predict disease severity and overall survival in chronic lymphocytic leukemia (CLL). The purpose of our study of 190 CLL patients was to compare immunoglobulin heavy chain variable region (IgV(H)) mutation status, cytogenetic a
Autor:
Marc C. Levesque, J. Brice Weinberg, Youwei Chen, Charles W. O’Loughlin, Bethany E. Beasley, Jon P. Gockerman, Joseph O. Moore, Alicia D. Volkheimer, Dipak K. Ghosh
Publikováno v:
Nitric Oxide. 14:49-50
Publikováno v:
Nitric Oxide. 14:51-52
Autor:
John C. Salerno, Youwei Chen, Bethany E. Beasley, Ning Jiang, J. Brice Weinberg, Dipak K. Ghosh
Publikováno v:
Free Radical Biology and Medicine. 51:1471
Erratum Erratum for “Inhibition of nitric oxide synthase by cobalamins and cobinamides,” [Free Radic. Biol. Med. 46:1626–1632, 2009] J. Brice Weinberg ⁎, Youwei Chen , Ning Jiang , Bethany E. Beasley , John C. Salerno , Dipak K. Ghosh a a Div
Autor:
Marc C. Levesque, Joseph O. Moore, Youwei Chen, Gina Vaccaro, Carlos M. DeCastro, Bethany E. Beasley, Louis F. Diehl, David A. Rizzieri, Alicia D. Volkheimer, Jon P. Gockerman, J. Brice Weinberg
Publikováno v:
Blood. 106:5010-5010
One of the complexities of chronic lymphocytic leukemia (CLL) is that some patients die early from the disease, while others identically staged by conventional means may live more than two decades. This has led to a search for prognostic indicators t