Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Bethany D. Harris"'
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Severe acute respiratory syndrome coronavirus-2 (SAR-CoV-2) causes coronavirus disease 2019 (COVID19) that is responsible for short and long-term disease, as well as death, in susceptible hosts. The receptor binding domain (RBD) of the SARS-CoV-2 Spi
Externí odkaz:
https://doaj.org/article/7606d0a652d34576a525c37b83a307db
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Severe acute respiratory syndrome coronavirus-2 (SAR-CoV-2) causes coronavirus disease 2019 (COVID19) that is responsible for short and long-term disease, as well as death, in susceptible hosts. The receptor binding domain (RBD) of the SARS-CoV-2 Spi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::005d2ca3016883f46388bd919e54cd20
https://doi.org/10.1101/2021.04.13.439681
https://doi.org/10.1101/2021.04.13.439681
Autor:
Mark R. Walter, Paul A. Goepfert, Ashlesha Deshpande, W. Winn Chatham, Bethany D. Harris, Srilalitha Kuruganti
Publikováno v:
Lupus
Background/objectiveType-I interferons contribute to pathogenesis in systemic lupus erythematosus, including nephritis. Interferons consist of a family of 16 proteins yet are often characterized in patients without knowledge of the specific interfero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ed25743875a15faba5f3b8663c9c4bd
https://europepmc.org/articles/PMC7427124/
https://europepmc.org/articles/PMC7427124/
Publikováno v:
Journal of Biological Chemistry. 293:16057-16068
IFNϵ and IFNκ are interferons that induce microbial immunity at mucosal surfaces and in the skin. They are members of the type-I interferon (IFN) family, which consists of 16 different IFNs, that all signal through the common IFNAR1/IFNAR2 receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9936ce3246133729e9819cda9afee8b6
https://doi.org/10.1074/jbc.ra118.003617
https://doi.org/10.1074/jbc.ra118.003617
Autor:
Bethany D. Harris, R. Mark L. Buller, Jeffrey A. Speir, Jill Schriewer, Shane Miersch, Sachdev S. Sidhu, Mark R. Walter, Ashlesha Deshpande, Srilalitha Kuruganti
Publikováno v:
Journal of Biological Chemistry. 291:447-461
Exogenous cytokine therapy can induce systemic toxicity, which might be prevented by activating endogenously produced cytokines in local cell niches. Here we developed antibody-based activators of cytokine signaling (AcCS), which recognize cytokines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eafec645956533e80e0f40782576ad9
https://doi.org/10.1074/jbc.m115.665943
https://doi.org/10.1074/jbc.m115.665943
Autor:
Mark R. Walter, Kanagalaghatta R. Rajashankar, Ashlesha Deshpande, Bethany D. Harris, Naomi J. Logsdon
Publikováno v:
Proceedings of the National Academy of Sciences. 109:12704-12709
Interleukin 20 (IL-20) is a pleotropic IL-10 family cytokine that protects epithelial surfaces from pathogens. However, dysregulated IL-20 signaling is implicated in several human pathologies including psoriasis, rheumatoid arthritis, atherosclerosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3354c374bcbf4d68ac6fac30ae825b30
https://doi.org/10.1073/pnas.1117551109
https://doi.org/10.1073/pnas.1117551109
Autor:
Mark R. Walter, Naomi J. Logsdon, Srilalitha Kuruganti, Brandi C. Jones, Sung-il Yoon, Bethany D. Harris
Publikováno v:
The Journal of biological chemistry. 287(32)
Human interleukin-10 (hIL-10) is a pleiotropic cytokine that is able to suppress or activate cellular immune responses to protect the host from invading pathogens. Epstein-Barr virus (EBV) encodes a viral IL-10 (ebvIL-10) in its genome that has retai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e03d98fde824d24f3828a40fd64dbf70
https://pubmed.ncbi.nlm.nih.gov/22692218
https://pubmed.ncbi.nlm.nih.gov/22692218
Autor:
Ashlesha Deshpande, Naomi J. Logsdon, Bethany D. Harris, Bin Gao, Svetlana Radaeva, Sung-il Yoon, Mark R. Walter, Brian Halloran, Brandi C. Jones
Publikováno v:
Structure (London, England : 1993). 18(5)
SummaryIL-10R2 is a shared cell surface receptor required for the activation of five class 2 cytokines (IL-10, IL-22, IL-26, IL-28, and IL-29) that play critical roles in host defense. To define the molecular mechanisms that regulate its promiscuous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7235a01537c4dce8078dca2acbb5536f
https://pubmed.ncbi.nlm.nih.gov/20462488
https://pubmed.ncbi.nlm.nih.gov/20462488