Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Bethany Brunton"'
Autor:
Rianna Vandergaast, Timothy Carey, Samantha Reiter, Chase Lathrum, Patrycja Lech, Clement Gnanadurai, Michelle Haselton, Jason Buehler, Riya Narjari, Luke Schnebeck, Anne Roesler, Kara Sevola, Lukkana Suksanpaisan, Alice Bexon, Shruthi Naik, Bethany Brunton, Scott C. Weaver, Grace Rafael, Sheryl Tran, Alina Baum, Christos A. Kyratsous, Kah Whye Peng, Stephen J. Russell
Publikováno v:
mSphere, Vol 6, Iss 3 (2021)
Since its emergence at the end of 2019, SARS-CoV-2, the causative agent of COVID-19, has caused over 100 million infections and 2.4 million deaths worldwide. Recently, countries have begun administering approved COVID-19 vaccines, which elicit strong
Externí odkaz:
https://doaj.org/article/fd6c7795e5dc4c6292e6a1ae0c6f3949
Autor:
Kai J Rogers, Bethany Brunton, Laura Mallinger, Dana Bohan, Kristina M Sevcik, Jing Chen, Natalie Ruggio, Wendy Maury
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 12, p e0007819 (2019)
BackgroundEbolavirus (EBOV) outbreaks, while sporadic, cause tremendous morbidity and mortality. No therapeutics or vaccines are currently licensed; however, a vaccine has shown promise in clinical trials. A critical step towards development of effec
Externí odkaz:
https://doaj.org/article/8d762ec8dd8e4e7196bda5352bc885fd
Autor:
Bethany Brunton, Kai Rogers, Elisabeth K Phillips, Rachel B Brouillette, Ruayda Bouls, Noah S Butler, Wendy Maury
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 6, p e0006983 (2019)
BackgroundT cell immunoglobulin mucin domain-1 (TIM-1) is a phosphatidylserine (PS) receptor, mediating filovirus entry into cells through interactions with PS on virions. TIM-1 expression has been implicated in Ebola virus (EBOV) pathogenesis; howev
Externí odkaz:
https://doaj.org/article/89c8289d298c42bc89c8d360269b55f1
Autor:
Joselle Cook, Kah Whye Whye Peng, Thomas E. Witzig, Stephen M Broski, Jose Caetano Villasboas, Jonas Paludo, Mrinal M Patnaik, vincent Vincent rajkumar, Angela Dispenzieri, Nelson Leung, Francis Buadi, Nora Nora Bennani, Stephen M. Ansell, Lianwen Zhang, Nandakumar Packiriswamy, Baskar Balakrishnan, Bethany Brunton, Marissa Giers, Brenda Ginos, Amylou C. Dueck, Susan Geyer, Morie A Gertz, Rahma Warsame, Ronald S. Go, Suzanne R Hayman, David Dingli, Shaji K Kumar, P. Leif Bergsagel, Javier Munoz, Wilson I Gonsalves, Taxiarchis V. Kourelis, Eli Muchtar, Prashant Kapoor, Robert A Kyle, Yi Lin, Mustaqeem Siddiqui, Amie Fonder, Miriam Hobbs, Yi Lisa Hwa, Shruthi Naik, Stephen J Russell, Martha Q Lacy
Publikováno v:
Blood Advances.
Clinical success with intravenous (IV) oncolytic virotherapy (OV) has to date been anecdotal. Here, we conducted a phase 1 clinical trial of systemic OV therapy and investigated the mechanisms of action in responding T-cell lymphoma (TCL) patients. A
Autor:
Scott H. Okuno, Yingke Zhou, Charles L. Loprinzi, MC Liu, Kathryn J. Ruddy, Prema P. Peethambaram, Nandakumar Packiriswamy, Bethany Brunton, Stephen J. Russell, Mark J. Federspiel, Eva Galanis, Joleen M. Hubbard, K-W Peng, Jacob B. Allred
Publikováno v:
Cancer Research. 79:P6-21
Background: The live attenuated non-pathogenic Edmonston MV vaccine strain has advantages as an oncolytic platform given its tumor specificity, potent bystander effect, and ability to be engineered and retargeted. MV-NIS expresses the human thyroidal
Autor:
Bethany Brunton, Rianna Vandergaast, Christos A. Kyratsous, Shruthi Naik, Grace H. Rafael, Riya Narjari, Sheryl Tran, Michelle Haselton, Scott C. Weaver, Lukkana Suksanpaisan, Anne Roesler, Alice Bexon, Kah Whye Peng, Kara Sevola, Samantha Reiter, Luke Schnebeck, Clement W. Gnanadurai, Patrycja J. Lech, Alina Baum, Stephen J. Russell, Timothy S. Carey, Chase Lathrum, Jason Buehler
Publikováno v:
mSphere, Vol 6, Iss 3 (2021)
Neutralizing antibodies are key determinants of protection from future infection, yet well-validated high-throughput assays for measuring titers of SARS-CoV-2-neutralizing antibodies are not generally available. Here, we describe the development and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68ea3c398d1af6cb1e50df577b958d24
https://doi.org/10.1101/2021.02.16.21251653
https://doi.org/10.1101/2021.02.16.21251653
Autor:
Bethany Brunton, Shruthi Naik, Rianna Vandergaast, Sheryl Tran, Scott C. Weaver, Christos A. Kyratsous, Timothy Carey, Alina Baum, Grace H. Rafael, John Mills, Samantha Reiter, Kah-Whye Peng, Jason Buehler, Alice Bexon, Michelle Haselton, Christopher Ziegler, Elitza S. Theel, Anne Roesler, Stephen J. Russell, Clement W. Gnanadurai, Rosa Maria Diaz, Lukkana Suksanpaisan, Clavin Jerde, Jordan Recker, Mulu Z. Tesfay, Matthew M. Roforth, Patrycja J. Lech
Publikováno v:
mSphere
bioRxiv
bioRxiv
Neutralizing antibodies are key determinants of protection from future infection, yet well-validated high-throughput assays for measuring titers of SARS-CoV-2-neutralizing antibodies are not generally available. Here, we describe the development and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68833cf8dc4c45f4629b6f7098f4f52f
https://doi.org/10.1101/2020.05.26.117549
https://doi.org/10.1101/2020.05.26.117549
Autor:
Jing Chen, Kai J. Rogers, Wendy Maury, Kristina M. Sevcik, Natalie Ruggio, Dana Bohan, Bethany Brunton, Laura N. Mallinger
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 12, p e0007819 (2019)
PLOS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
PLOS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Background Ebolavirus (EBOV) outbreaks, while sporadic, cause tremendous morbidity and mortality. No therapeutics or vaccines are currently licensed; however, a vaccine has shown promise in clinical trials. A critical step towards development of effe
Autor:
Mrinal M. Patnaik, Jose C. Villasboas, Bethany Brunton, Marissa Giers, Francis K. Buadi, David Dingli, Wilson I. Gonsalves, Amie Fonder, Nelson Leung, Yi Lin, Shaji Kumar, Amylou C. Dueck, Suzanne R. Hayman, P. Leif Bergsagel, Angela Dispenzieri, Rahma Warsame, Mustaqeem A. Siddiqui, Yi L. Hwa, Robert A. Kyle, Stephen J. Russell, Jonas Paludo, Stephen M. Ansell, Prashant Kapoor, Stephen M. Broski, Brenda Ginos, Susan Geyer, Thomas E. Witzig, Morie A. Gertz, S. Vincent Rajkumar, Ronald S. Go, Kah-Whye Peng, Miriam Hobbs, Eli Muchtar, Martha Q. Lacy, Joselle Cook, Taxiarchis Kourelis, N. Nora Bennani, Baskar Balakrishnan, Nandakumar Pakiriswamy, Lianwen Zhang
Publikováno v:
Blood. 138:1333-1333
Introduction: Factors contributing to the antitumor activity of systemic oncolytic virotherapy (OV) include (i) generalized innate immune activation due to virus infusion; (ii) direct oncolytic and/or immune-mediated destruction of OV infected tumor
Autor:
Tina Arkee, Gail A. Bishop, Wendy Maury, Kai J. Rogers, Bethany Brunton, Olena Shtanko, Noah S. Butler, Laura L. Stunz, Laura N. Mallinger, Dana Bohan, Judith M. White, Megan E. Schmidt, Steve M. Varga
Publikováno v:
J Leukoc Biol
Many acute viral infections target tissue macrophages, yet the mechanisms of macrophage-mediated control of viruses are poorly understood. Here, we report that CD40 expressed by peritoneal macrophages restricts early infection of a broad range of RNA