Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Bethany Almeida"'
Publikováno v:
Mechanobiology in Medicine, Vol 3, Iss 1, Pp 100111- (2025)
Human mesenchymal stem cells (hMSCs) have immense wound healing potential due to their immunomodulatory behavior. To control this behavior and reduce heterogeneity, researchers look to biomaterials, as matrix stiffness and viscoelasticity have been s
Externí odkaz:
https://doaj.org/article/d48c59863c854c5dad886e919208ffee
Publikováno v:
Bioengineering & Translational Medicine, Vol 9, Iss 1, Pp n/a-n/a (2024)
Abstract Historically, treatment of chronic, nonhealing wounds has focused on managing symptoms using biomaterial‐based wound dressings, which do not adequately address the underlying clinical issue. Mesenchymal stem cells (MSCs) are a promising ce
Externí odkaz:
https://doaj.org/article/668c96fbb3584a99a72631971455cc08
Publikováno v:
Pharmaceuticals, Vol 15, Iss 5, p 604 (2022)
The elevated intracellular production of or extracellular exposure to reactive oxygen species (ROS) causes oxidative stress to cells, resulting in deleterious irreversible biomolecular reactions (e.g., lipid peroxidation) and disease progression. The
Externí odkaz:
https://doaj.org/article/08b0adb5f538454eb54e6f39dde0c616
Publikováno v:
Molecules, Vol 25, Iss 23, p 5672 (2020)
In nanoparticle (NP)-mediated drug delivery, liposomes are the most widely used drug carrier, and the only NP system currently approved by the FDA for clinical use, owing to their advantageous physicochemical properties and excellent biocompatibility
Externí odkaz:
https://doaj.org/article/ac33ea301fe14af9acc58ac9f53eb9d6
Publikováno v:
Bioconjugate Chemistry. 33:263-271
Bioorthogonal click chemistry, first introduced in the early 2000s, has become one of the most widely used approaches for designing advanced biomaterials for applications in tissue engineering and regenerative medicine, due to the selectivity and bio
Publikováno v:
ACS Sensors. 6:1695-1703
Nitric oxide (NO) is a critical cell signaling molecule with important roles in both normal cellular physiology and pathology. Over the past 20 years, multiple sensing modalities have been developed for the intracellular synthesis (endogenous) and re
Autor:
Bethany Almeida, Okhil K. Nag, James B. Delehanty, Alan L. Huston, Igor L. Medintz, Megan E. Muroski, David A. Hastman
Publikováno v:
ACS Nano. 14:2659-2677
The interfacing of nanoparticle (NP) materials with cells, tissues, and organisms for a range of applications including imaging, sensing, and drug delivery continues at a rampant pace. An emerging theme in this area is the use of NPs and nanostructur
Publikováno v:
Annals of Biomedical Engineering. 48:2090-2102
Clinical trials with mesenchymal stem cells (MSCs) have demonstrated potential to treat osteoarthritis, a debilitating disease that affects millions. However, these therapies are often less effective due to heterogeneous MSC differentiation. Kartogen
Publikováno v:
Chemical communications (Cambridge, England). 56(55)
We introduce an innovative approach to adhere mesenchymal stem cells (MSCs) to a hydrogel scaffold by nucleating adhesion through strain-promoted click chemistry. This method yields a significant increase in cell viability compared to non-functionali
Autor:
Anita Shukla, Bethany Almeida
Publikováno v:
Journal of Biomedical Materials Research Part A. 105:464-474
Alkanethiol self-assembled monolayers (SAMs) have been used extensively in studying the role of surface functionality and geometry on stem cell differentiation; however, the effects of stem cell culture conditions on SAM stability over time are not w