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pro vyhledávání: '"Bethann N. Johnson"'
Autor:
Bethann N. Johnson, Bryan K. Yamamoto
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 335:180-189
Stress facilitates drug abuse by humans. In rodents, stress enhances the neurochemical, neuroendocrine, and behavioral responses to psychostimulants. Although chronic unpredictable stress (CUS) enhances the acute hyperthermic and long-term monoamine-
Publikováno v:
Cell Death & Disease
Parkinson’s disease (PD) is the second most prevalent neurodegenerative disorder, affecting 1–3% of the population over 65. Mutations in the ubiquitin E3 ligase parkin are the most common cause of autosomal recessive PD. The parkin protein posses
Publikováno v:
BioMed Research International, Vol 2014 (2014)
BioMed Research International
BioMed Research International
MDMA (3,4-methylenedioxymethamphetamine) is a substituted amphetamine and popular drug of abuse. Its mood-enhancing short-term effects may prompt its consumption under stress. Clinical studies indicate that MDMA treatment may mitigate the symptoms of
Autosomal recessive loss-of-function mutations within the PARK2 gene functionally inactivate the E3 ubiquitin ligase parkin, resulting in neurodegeneration of catecholaminergic neurons and a familial form of Parkinson disease. Current evidence sugges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cf5119d5d80c93023c30a88eb2179e7
https://europepmc.org/articles/PMC3341078/
https://europepmc.org/articles/PMC3341078/
Autor:
Bryan K. Yamamoto, Bethann N. Johnson
Publikováno v:
Neuroscience. 159(4)
Exposure to stress alters the behavioral and neurochemical effects of drugs of abuse. However, it is unknown if chronic stress can affect the serotonergic depletions induced by the psychostimulant drug 3,4-methylenedioxymethamphetamine (MDMA). Rats w
Publikováno v:
Cell Cycle
literature predicting a direct downstream function within a highly conserved cell death pathway. Soon after the cloning of the PARKIN gene, numerous studies shed light on the function of parkin. Parallel efforts from many groups also revealed that pa
Autor:
Bethann N. Johnson, Marcie A. Glicksman, Scott A. Shaffer, Stephen Douthwright, Justin D. Boyd, Catherine L. Ward, Kristin J. Boggio, Daryl A. Bosco, John Landers
Publikováno v:
Cell Death & Disease
Fused in sarcoma/translocated in liposarcoma (FUS/TLS or FUS) is a multifunctional RNA/DNA-binding protein that is pathologically associated with cancer and neurodegeneration. To gain insight into the vital functions of FUS and how a loss of FUS func