Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Bethanie E. Wilkinson"'
Autor:
Gale Smith, Vivek Shinde, Shane Cloney-Clark, Bethanie E. Wilkinson, Cheryl Keech, Pedro A. Piedra, Mingzhu Zhu, Joyce S Plested, Haixia Zhou, Louis Fries, Matthew B. Frieman, Neil Formica, Andreana Robertson, Paul M. Griffin, Jason D. Lickliter, Marisa McGrath, James Logue, Gary Albert, Nita Patel, Maggie Lewis, Stuart Weston, Patricia Price-Abbott, Susan Neal, Gregory M. Glenn, Iksung Cho, Robert Haupt, Patricia Reed, Chinar Desai, Kathleen Callahan
Publikováno v:
New England Journal of Medicine
The New England Journal of Medicine
The New England Journal of Medicine
Background NVX-CoV2373 is a recombinant severe acute respiratory syndrome coronavirus 2 (rSARS-CoV-2) nanoparticle vaccine composed of trimeric full-length SARS-CoV-2 spike glycoproteins and Matrix-M1 adjuvant. Methods We initiated a randomized, plac
Autor:
Juliette Thompson, David L. Lakey, Edith C. Sannella, Robert F. Betts, Gale Smith, John J. Treanor, Peter F. Wright, George Reed, Bethanie E. Wilkinson
Publikováno v:
Journal of Infectious Diseases. 174:838-841
In a prospective double-blind trial, the reactogenicity and immunogenicity of recombinant baculovirus influenza A vaccines containing purified full-length hemagglutinin (HA) were compared with standard trivalent inactivated vaccine (TIV). The recombi
Autor:
John J. Treanor, Bethanie E. Wilkinson, Robert B. Belshe, Gale Smith, Craig Stanway Hackett, Douglas C. Powers, Edwin L. Anderson, Robert F. Betts
Publikováno v:
Journal of Infectious Diseases. 173:1467-1470
Healthy subjects45 years old (young adults) or65 (elderly adults) were randomized in double-blind fashion to receive intramuscularly subvirion trivalent influenza vaccine, placebo, or 15, 45, or 135 microgram of the hemagglutinin (HA) of the influenz
Autor:
Joel M. Kremer, Stanley Cohen, Bethanie E. Wilkinson, Carol A. Connell, David Gruben, Keith S. Kanik, Samuel H. Zwillich
Publikováno v:
Arthritis & Rheumatism. 64:3056-3057
Autor:
Mark Wolff, Jean Hu-Primmer, John J. Treanor, Feda Masseoud, Bethanie E. Wilkinson, Diane O'Brien, Rosalyn Battaglia, Gina Rabinovich, Jacqueline M. Katz, William C. Blackwelder
Publikováno v:
Vaccine. 19(13-14)
Recent outbreaks of avian influenza in humans have demonstrated the need for vaccines for influenza viruses with pandemic potential. Recombinant hemagglutinins are an attractive option for such vaccines because they do not require handling potentiall
Autor:
Bethanie E. Wilkinson, Henry D. Stone, Maricarmen García, Gale Smith, John M. Crawford, Michael L. Perdue, Andrei Vosnesensky
Publikováno v:
Vaccine. 17(18)
Baculoviruses were engineered to express hemagglutinin (HA) genes of recent avian influenza (AI) isolates of the H5 and H7 subtypes. The proteins were expressed as either intact (H7) or slightly truncated versions (H5). In both cases purified HA prot
Autor:
Douglas C. Powers, Craig M. Upshaw, Janet E. McElhaney, Mary C. Manning, Oscar A. Florendo, David W. Bentley, Bethanie E. Wilkinson
Publikováno v:
The Journal of infectious diseases. 175(2)
Adults were immunized with either baculovirus-expressed, purified recombinant hemagglutinin (rHA) from influenza A/Beijing/32/92 (H3N2) virus or saline placebo and evaluated for humoral and in vitro cellular immune responses. Compared with responses
Autor:
John J. Treanor, Bethanie E. Wilkinson, Volvovitz Franklin, Craig Stanway Hackett, Robert B. Belshe, Douglas C. Powers, Gale Smith, Donald J. Kennedy, Edwin L. Anderson
Publikováno v:
The Journal of infectious diseases. 171(6)
This study evaluated the safety, immunogenicity, and protective efficacy of vaccines containing purified recombinant uncleaved hemagglutinin (rHA0) from influenza A/Beijing/32/92 (H3N2) virus. In a randomized, double-blinded trial, 127 adult voluntee