Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Beth M. French"'
Autor:
Shilpa D. Kadam, Beth M. French, S-T. Kim, Christy M. Morris-Berry, Andrew W. Zimmerman, Mary E. Blue, Harvey S. Singer
Publikováno v:
Journal of Experimental Neuroscience, Vol 7 (2013)
Auto antibodies found in the mothers of children with autistic disorder (MCAD) when passively transferred to pregnant mice cause behavioral alterations in juvenile and adult offspring. The goal of this study was to identify whether intraperitoneal in
Externí odkaz:
https://doaj.org/article/2ca56fddd27348d5a70240b7394d1c73
Autor:
Zahra A. Habibabady, Selin Sendil, Felix Ellett, Franziska Pollok, Gabriela F. Elias, Beth M. French, Wenji Sun, Gheorghe Braileanu, Lars Burdorf, Daniel Irimia, Richard N. Pierson, Agnes M. Azimzadeh
Publikováno v:
Xenotransplantation
Platelet sequestration is a common process during organ reperfusion after transplantation. However, instead of lower platelet counts, when using traditional hemocytometers and light microscopy, we observed physiologically implausible platelet counts
Autor:
Kevin J. Quinn, Lars Burdorf, Elizabeth Kang, Agnes M. Azimzadeh, Beth M. French, Richard N. Pierson, David Ayares, Evan A Schwartz, Donald G. Harris, Siamak Dahi, Carol Phelps
Publikováno v:
Xenotransplantation. 22:102-111
Background Genetically modified pigs are a promising potential source of lung xenografts. Ex vivo xenoperfusion is an effective platform for testing the effect of new modifications, but typical experiments are limited by testing of a single genetic i
Publikováno v:
Xenotransplantation
Presentation of sialic acid (Sia) varies among different tissues and organs within each species, and between species. This diversity has biologically important consequences regarding the recognition of cells by "xeno" antibodies (Neu5Gc vs Neu5Ac). S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b9b9e4634fcad98d5030f721595997e
https://europepmc.org/articles/PMC10167934/
https://europepmc.org/articles/PMC10167934/
Autor:
Xiangfei Cheng, Lars Burdorf, Richard N. Pierson, Jolene Ranek, Christopher Laird, Benjamin Cerel, Agnes M. Azimzadeh, Krishna Mohan Sepuru, Emily Redding, Donald G. Harris, Beth M. French, Selin Sendil, Krishna Rajarathnam, Yuming Zhao
Publikováno v:
Xenotransplantation. 25(2)
BACKGROUND: Human neutrophils are sequestered by pig lung xenografts within minutes during ex vivo perfusion. This phenomenon is not prevented by pig genetic modifications that remove xeno-antigens or added human regulatory molecules intended to down
Autor:
Xiangfei Cheng, Richard N. Pierson, Natalia Kubicki, Arielle Cimeno, Gheorghe Braileanu, Carol Phelps, Lars Burdorf, Beth M. French, Andrea Bähr, Christopher Laird, Edward So, David Ayares, Dawn Parsell, Wenji Sun, Natalie A. O'Neill, Nikolai Klymiuk, Agnes M. Azimzadeh
Publikováno v:
Xenotransplantation. 24(2)
Background: Lung xenografts remain susceptible to loss of vascular barrier function within hours in spite of significant incremental advances based on genetic engineering to remove the Gal 1,3-Gal antigen (GalTKO) and express human membrane cofactor
Autor:
Beth M. French, Xiangfei Cheng, Agnes M. Azimzadeh, David Ayares, Dawn Parsell, Arielle Cimeno, William E. Fogler, John L. Magnani, Carol Phelps, Christopher Laird, Richard N. Pierson, Natalie A. O'Neill, Wessam Hassanein, Lars Burdorf
Publikováno v:
Xenotransplantation
BACKGROUND: Alongside the need to develop more effective and less toxic immunosuppression, the shortage of human organs available for organ transplantation is one of the major hurdles facing the field. Research into xenotransplantation, as an alterna
Autor:
Natalie A. O'Neill, Christopher Laird, Beth M. French, Rolf N. Barth, Richard N. Pierson, Agnes M. Azimzadeh, John C. LaMattina, David Ayares, Arielle Cimeno, Jessica M. Powell, Carol Phelps
Publikováno v:
Xenotransplantation. 25:e12361
In addition to immune barriers, molecular incompatibilities between species are predicted to limit pig liver survival in primate xenotransplantation models. Assessment and measurement of synthetic function of genetically modified porcine livers after
Autor:
Xiangfei Cheng, Dawn Parsell, Emily Redding, Agnes M. Azimzadeh, Mehmet C. Uluer, Beth M. French, Arielle Cimeno, Kathryn Thomas, Christopher Laird, Olga Goloubeva, Richard N. Pierson, Rolf N. Barth, Ivan Tatarov, Wessam Hassanein, David Ayares, Alena Hershfeld, Jagdeece Ramsoondar, Natalie A. O'Neill, Todd Vaught, Jessica M. Powell, John C. LaMattina, Lars Burdorf, Kasinath Kuravi
Publikováno v:
Xenotransplantation. 24:e12339
Background Wild-type pigs express several carbohydrate moieties on their cell surfaces that differ from those expressed by humans. This difference in profile leads to pig tissue cell recognition of human blood cells causing sequestration, in addition
Publikováno v:
The FASEB Journal. 28
Objective: Transplantation of organs across species, xenotransplantation, is limited by the sequestration of platelets and neutrophils in injured organs; we hypothesized that sialic acids on porcine endothelial cells affects adhesion of human neutrop