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Akademický článek

The type III secreted effector DspE is required early in solanum tuberosum leaf infection by Pectobacterium carotovorum to cause cell death, and requires Wx(3-6)D/E motifs.

Autor: Clifford S Hogan, Beth M Mole, Sarah R Grant, David K Willis, Amy O Charkowski

Publikováno v: PLoS ONE, Vol 8, Iss 6, p e65534 (2013)

Pectobacterium species are enterobacterial plant-pathogens that cause soft rot disease in diverse plant species. Unlike hemi-biotrophic plant pathogenic bacteria, the type III secretion system (T3SS) of Pectobacterium carotovorum subsp. carotovorum (

Externí odkaz: https://doaj.org/article/93465a6278d24079a54619b8dff1f279

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Action at a Distance: Amino Acid Substitutions That Affect Binding of the Phosphorylated CheY Response Regulator and Catalysis of Dephosphorylation Can Be Far from the CheZ Phosphatase Active Site

Autor: Beth M. Mole, Ashalla M. Freeman, Ruth E. Silversmith, Robert B. Bourret

Publikováno v: Journal of Bacteriology. 193:4709-4718

Two-component regulatory systems, in which phosphorylation controls the activity of a response regulator protein, provide signal transduction in bacteria. For example, the phosphorylated CheY response regulator (CheYp) controls swimming behavior. In

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37ba441c3d823108a0a48585ea08a310
https://doi.org/10.1128/jb.00070-11

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Niche-Specificity and the Variable Fraction of the Pectobacterium Pan-Genome

Autor: Beth M. Mole, M. Marquez-Villavicencio, Bryan S. Biehl, Bing Ma, Amy O. Charkowski, X. Yi, Jeremy D. Glasner, Jeffery L. Dangl, Sarah R. Grant, Ching-Hong Yang, H.-S. Kim, Nicole T. Perna, Anna I. Rissman, Courtney E. Jahn

Publikováno v: Molecular Plant-Microbe Interactions®. 21:1549-1560

We compare genome sequences of three closely related soft-rot pathogens that vary in host range and geographical distribution to identify genetic differences that could account for lifestyle differences. The isolates compared, Pectobacterium atrosept

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c372e4f0f6ab988ac15d39cc176484c0
https://doi.org/10.1094/mpmi-21-12-1549

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Novel 180- and 480-Base-Pair Insertions in African and African-American Strains of Helicobacter pylori

Autor: Beth M. Mole, Richard M. Peek, Erik M. Lenarcic, Mark H. Forsyth, Richard A. Adegbola, Reid Ally, Julian Thomas, Ousman Secka, Rajesh S. Mistry, Issy Segal, Daiva Dailidiene, Shannon L. McNulty, Douglas E. Berg

Publikováno v: Journal of Clinical Microbiology. 42:5658-5663

Helicobacter pylori is a genetically diverse bacterial species that chronically infects human stomachs and sometimes causes severe gastroduodenal disease. Studies of polymorphic DNA sequences can suggest geographic origins of individual strains. Here

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f324b1788b928f6db32a98219ae2b91e
https://doi.org/10.1128/jcm.42.12.5658-5663.2004

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Gluconate metabolism is required for virulence of the soft-rot pathogen Pectobacterium carotovorum

Autor: Beth M. Mole, Sohrab Habibi, Jeffery L. Dangl, Sarah R. Grant

Publikováno v: Molecular plant-microbe interactions : MPMI. 23(10)

Pectobacterium carotovorum is a ubiquitous soft rot pathogen that uses global virulence regulators to coordinate pathogenesis in response to undefined environmental conditions. We characterize an operon in P. carotovorum required for gluconate metabo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb0217fff344dde2c99035d17b10251a
https://pubmed.ncbi.nlm.nih.gov/20636105

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GABAA Receptor Regulation of Voluntary Ethanol Drinking Requires PKCε

Autor: Clyde W. Hodge, Veronique Lepoutre, Joyce Besheer, Beth M. Mole

Protein kinase C (PKC) regulates a variety of neural functions, including ion channel activity, neurotransmitter release, receptor desensitization and differentiation. We have shown previously that mice lacking the epsilon-isoform of PKC (PKCepsilon)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7654e5237d309c21382587471e472fe4
https://europepmc.org/articles/PMC2864065/

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Subterfuge and manipulation: type III effector proteins of phytopathogenic bacteria

Autor: Jeffery L. Dangl, Sarah R. Grant, Beth M. Mole, Jeff H. Chang, Emily J. Fisher

Publikováno v: Annual review of microbiology. 60

Diverse gram-negative bacteria deliver effector proteins into the cells of their eukaryotic hosts using the type III secretion system. Collectively, these type III effector proteins function to optimize the host cell environment for bacterial growth.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::263a5962e2e34367cb4b7cf6f8f31ca4
https://pubmed.ncbi.nlm.nih.gov/16753033

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The Type III Secreted Effector DspE Is Required Early in Solanum tuberosum Leaf Infection by Pectobacterium carotovorum to Cause Cell Death, and Requires Wx(3–6)D/E Motifs

Autor: Amy O. Charkowski, David K. Willis, Sarah R. Grant, Beth M. Mole, Clifford S. Hogan

Publikováno v: PLoS ONE
PLoS ONE, Vol 8, Iss 6, p e65534 (2013)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b719d8e203170972d2d4589764121130
https://doi.org/10.1371/journal.pone.0065534

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