Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Beth Lockwood"'
Autor:
Lyndsey A. Reich, Jessica A. Moerland, Ana S. Leal, Di Zhang, Sarah Carapellucci, Beth Lockwood, Peter W. Jurutka, Pamela A. Marshall, Carl E. Wagner, Karen T. Liby
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Rexinoids are ligands which activate retinoid X receptors (RXRs), regulating transcription of genes involved in cancer-relevant processes. Rexinoids have anti-neoplastic activity in multiple preclinical studies. Bexarotene, used to treat cut
Externí odkaz:
https://doaj.org/article/f8d56ac022b34151adecde4d1fbfa621
Autor:
Jessica A. Moerland, Di Zhang, Lyndsey A. Reich, Sarah Carapellucci, Beth Lockwood, Ana S. Leal, Teresa Krieger-Burke, Bilal Aleiwi, Edmund Ellsworth, Karen T. Liby
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Abstract Effective drugs are needed for lung cancer, as this disease remains the leading cause of cancer-related deaths. Rexinoids are promising drug candidates for cancer therapy because of their ability to modulate genes involved in inflammation, c
Externí odkaz:
https://doaj.org/article/6d8fd743dcf44e9bbf89c3d1f8bcd6a9
Autor:
Jessica A. Moerland, Ana S. Leal, Beth Lockwood, Elena Y. Demireva, Huirong Xie, Teresa Krieger-Burke, Karen T. Liby
Publikováno v:
Antioxidants, Vol 12, Iss 1, p 116 (2023)
The NRF2/KEAP1 pathway protects healthy cells from malignant transformation and maintains cellular homeostasis. Up to 30% of human lung tumors gain constitutive NRF2 activity which contributes to cancer cell survival and chemoresistance, but the effe
Externí odkaz:
https://doaj.org/article/758e751f9a254e85957c4cb170a579c6
Autor:
Sarah Carapellucci, Karen T. Liby, Carl E. Wagner, Peter W. Jurutka, Jessica A. Moerland, Pamela A. Marshall, Lyndsey A. Reich, Ana S. Leal, Di Zhang, Beth Lockwood
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Scientific Reports
Scientific Reports
Rexinoids are ligands which activate retinoid X receptors (RXRs), regulating transcription of genes involved in cancer-relevant processes. Rexinoids have anti-neoplastic activity in multiple preclinical studies. Bexarotene, used to treat cutaneous T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f13d5dfb3d9cd226c60a7167b651af6
https://doi.org/10.21203/rs.3.rs-826798/v1
https://doi.org/10.21203/rs.3.rs-826798/v1
Autor:
Lyndsey A. Reich, Sarah Carapellucci, Teresa Krieger-Burke, Jessica A. Moerland, Di Zhang, Edmund Ellsworth, Ana S. Leal, Beth Lockwood, Bilal Aleiwi, Karen T. Liby
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Effective drugs are needed for lung cancer, as this disease remains the leading cause of cancer-related deaths. Rexinoids are promising drug candidates for cancer therapy because of their ability to modulate genes involved in inflammation, cell proli
Autor:
Teresa Krieger-Burke, Edmund Ellsworth, Jessica A. Moerland, Di Zhang, Bilal Aleiwi, Ana S. Leal, Karen T. Liby, Beth Lockwood, Sarah Carapellucci
Publikováno v:
Cancers
Volume 13
Issue 19
Cancers, Vol 13, Iss 5004, p 5004 (2021)
Volume 13
Issue 19
Cancers, Vol 13, Iss 5004, p 5004 (2021)
(1) Background: Notwithstanding numerous therapeutic advances, 176,000 deaths from breast and lung cancers will occur in the United States in 2021 alone. The tumor microenvironment and its modulation by drugs have gained increasing attention and rele
Publikováno v:
Fundamental and Applied Toxicology. 23:470-475
Since polycyclic aromatic hydrocarbons (PAHs) are known to have epigenetic effects, we evaluated the effect of the parent chemical and the ozonated products on in vitro cell to cell communication bioassays which measures a nongenotoxic event. The scr
Autor:
Reich, Lyndsey A.1 (AUTHOR), Leal, Ana S.1 (AUTHOR), Ellsworth, Edmund1,2 (AUTHOR), Liby, Karen T.1,3 (AUTHOR) libykare@msu.edu
Publikováno v:
International Journal of Molecular Sciences. Mar2023, Vol. 24 Issue 5, p4298. 17p.
Autor:
Moerland, Jessica A., Liby, Karen T.
Publikováno v:
Antioxidants; Jun2024, Vol. 13 Issue 6, p621, 25p