Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Beth Kempton"'
Autor:
Junghyun Ryu, John P. Statz, William Chan, Fernanda C. Burch, John V. Brigande, Beth Kempton, Edward V. Porsov, Lauren Renner, Trevor McGill, Benjamin J. Burwitz, Carol B. Hanna, Martha Neuringer, Jon D. Hennebold
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Mutations in the MYO7A gene lead to Usher syndrome type 1B (USH1B), a disease characterized by congenital deafness, vision loss, and balance impairment. To create a nonhuman primate (NHP) USH1B model, CRISPR/Cas9 was used to disrupt MYO7A in
Externí odkaz:
https://doaj.org/article/5a7465c0a8444145a84a6c18f325d2dc
Autor:
Rosemary J Steinbach, Nicole N Haese, Jessica L Smith, Lois M A Colgin, Rhonda P MacAllister, Justin M Greene, Christopher J Parkins, J Beth Kempton, Edward Porsov, Xiaojie Wang, Lauren M Renner, Trevor J McGill, Brandy L Dozier, Craig N Kreklywich, Takeshi F Andoh, Marjorie R Grafe, Heidi L Pecoraro, Travis Hodge, Robert M Friedman, Lisa A Houser, Terry K Morgan, Peter Stenzel, Jonathan R Lindner, Robert L Schelonka, Jonah B Sacha, Victoria H J Roberts, Martha Neuringer, John V Brigande, Christopher D Kroenke, Antonio E Frias, Anne D Lewis, Meredith A Kelleher, Alec J Hirsch, Daniel Neal Streblow
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0227676 (2020)
Zika virus infection during pregnancy is associated with miscarriage and with a broad spectrum of fetal and neonatal developmental abnormalities collectively known as congenital Zika syndrome (CZS). Symptomology of CZS includes malformations of the b
Externí odkaz:
https://doaj.org/article/688f3ed75b8e4070a6d4c5a323b83250
Autor:
Dennis R. Trune, Carol J. MacArthur, Fran Hausman, Dongseok Choi, Katherine D. Shives, J. Beth Kempton
Publikováno v:
Annals of Otology, Rhinology & Laryngology. 128:134S-138S
Objectives: Glucocorticoids are given for sensorineural hearing loss, but little is known of their molecular impact on the inner ear. Furthermore, in spite of claims of improved hearing recovery with intratympanic delivery of steroids, no studies hav
Autor:
Beth Kempton
This book invites you to cultivate stillness and contentment in an ever-changing, uncertain world, inspired by ancient and contemporary Japanese wisdom. Drawing on a thousand years of Japanese literature, culture, and philosophical ideas to explore t
Autor:
John V. Brigande, J. Beth Kempton, Jennifer J Lentz, Francine M. Jodelka, Alev M Brigande, Rachel A. Dumont, Lingyan Wang, Frank Rigo, Michelle L. Hastings, Han Jiang
Publikováno v:
Nucleic Acids Research
Disabling hearing loss impacts ∼466 million individuals worldwide with 34 million children affected. Gene and pharmacotherapeutic strategies to rescue auditory function in mouse models of human deafness are most effective when administered before h
Autor:
Craig N. Kreklywich, Christopher J. Parkins, Robert L. Schelonka, John V. Brigande, Lisa A Houser, Anne D. Lewis, Jessica L. Smith, Brandy L. Dozier, Meredith A. Kelleher, Marjorie R. Grafe, Terry K. Morgan, Victoria H. J. Roberts, Lauren Renner, Xiaojie Wang, Alec J. Hirsch, Heidi L. Pecoraro, Trevor J. McGill, Peter Stenzel, Travis Hodge, Jonathan R. Lindner, Rosemary J. Steinbach, Daniel N. Streblow, Lois M. A. Colgin, Takeshi F. Andoh, Martha Neuringer, Nicole N. Haese, Jonah B. Sacha, Edward Porsov, Christopher D. Kroenke, Rhonda MacAllister, Antonio E. Frias, J. Beth Kempton, Robert M. Friedman, Justin M. Greene
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 1, p e0227676 (2020)
PLoS ONE, Vol 15, Iss 1, p e0227676 (2020)
Zika virus infection during pregnancy is associated with miscarriage and with a broad spectrum of fetal and neonatal developmental abnormalities collectively known as congenital Zika syndrome (CZS). Symptomology of CZS includes malformations of the b
Autor:
Beth Kempton, Tomonari Hayama, Mohammed Nasser, Thanasup Gonmanee, Yeon-Mi Lee, John V. Brigande, Ying Li, Hong Ma, Riffat Ahmed, Paula Amato, Hayley Darby, Crystal Van Dyken, Trevor J. McGill, Andre Terzic, Amy Koski, Eunju Kang, Michael D. Andrews, Satsuki Yamada, Shoukhrat Mitalipov, Nuria Marti Gutierrez, Dan Liang
Publikováno v:
Biol Reprod
Heritable mitochondrial DNA (mtDNA) mutations are common, yet only a few recurring pathogenic mtDNA variants account for the majority of known familial cases in humans. Purifying selection in the female germline is thought to be responsible for the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7120e71136c4b9bddb1a2ebca247bffd
https://europepmc.org/articles/PMC7068114/
https://europepmc.org/articles/PMC7068114/
Autor:
Beth Kempton
A delightful guide to a holiday season filled with mindfulness, self-care, and joy.At the end of a difficult year, what if this December were soothing instead of stressful? Celebrate a new kind of holiday season this winter—one where you radiate ca
Autor:
Beth Kempton
Wabi Sabi ist ein jahrhundertealtes Konzept, das Schönheit in der Unvollkommenheit erkennt und die Vergänglichkeit aller Dinge akzeptiert. Damit ist es das ideale Gegengift zu unserer perfektionistischen, konsumorientierten Zeit. Die Japanologin Be
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience
Therapeutic strategies to restore hearing and balance in mouse models of inner ear disease aim to rescue sensory function by gene replacement, augmentation, knock down or knock out. Modalities to achieve therapeutic effects have utilized virus-mediat