Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Beth K. Rycroft"'
Publikováno v:
The Journal of Physiology. 590:1655-1667
Key points • The nociceptin/ORL1 receptor neuropeptide system is related to opioid systems and thought to be involved in pain modulation. • A major mechanism of action of this system is inhibition of calcium channels that control excitability of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be5cf286a3ce5998588b964853ca0963
https://doi.org/10.1113/jphysiol.2012.228429
https://doi.org/10.1113/jphysiol.2012.228429
Publikováno v:
The Journal of Physiology. 586:515-527
Glutamate receptor response properties of nociceptive synapses on neurokinin 1 receptor positive (NK1R+) lamina I neurons were determined 3 days after induction of chronic peripheral inflammation with Freund's Complete Adjuvant (CFA). A significant i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba12ade03d2f1dcd56d3b6e5284c35af
https://doi.org/10.1113/jphysiol.2007.145581
https://doi.org/10.1113/jphysiol.2007.145581
Publikováno v:
The Journal of Physiology. 580:883-894
N-type calcium channels contribute to the release of glutamate from primary afferent terminals synapsing onto nocisponsive neurons in the dorsal horn of the spinal cord, but little is known of functional adaptations to these channels in persistent pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fed19655f47db1fbb8a47771cc7f72c2
https://doi.org/10.1113/jphysiol.2006.125880
https://doi.org/10.1113/jphysiol.2006.125880
Autor:
Beth K. Rycroft, Alasdair J. Gibb
Publikováno v:
Neuropharmacology. 47:505-514
Calcineurin, protein phosphatase 2B, is a calcium-binding protein that has been shown to modulate NMDA receptor activity (Regulation of NMDA channel function by endogenous Ca2+-dependent phosphatase. Nature 369 (1994) 235; Regulation of glycine-insen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10e52051ba2809b0d3bb7d8ba75d301f
https://doi.org/10.1016/j.neuropharm.2004.06.001
https://doi.org/10.1016/j.neuropharm.2004.06.001
Autor:
Beth K. Rycroft, Alasdair J. Gibb
Publikováno v:
The Journal of Physiology. 557:795-808
The NMDA receptor is modulated by changes in the intracellular calcium concentration, through activation of various intracellular calcium-dependent proteins. We have investigated regulation of single NMDA receptor channel activity by the calcium-sens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46803f9a5545ae4575734fd424faeccd
https://doi.org/10.1113/jphysiol.2003.059212
https://doi.org/10.1113/jphysiol.2003.059212
Publikováno v:
The Journal of physiology. 590(7)
The opioid-related receptor, ORL1, is activated by the neuropeptide nociceptin/orphanin FQ (N/OFQ) and inhibits high-voltage-activated (HVA) calcium channel currents (I(Ca)) via a G-protein-coupled mechanism. Endocytosis of ORL1 receptor during prolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::06c69b23519f3fb84ab8a6a27e9b0673
https://pubmed.ncbi.nlm.nih.gov/22371475
https://pubmed.ncbi.nlm.nih.gov/22371475
Publikováno v:
The Journal of physiology. 586(2)
Glutamate receptor response properties of nociceptive synapses on neurokinin 1 receptor positive (NK1R+) lamina I neurons were determined 3 days after induction of chronic peripheral inflammation with Freund's Complete Adjuvant (CFA). A significant i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::54137c69ea971ebc6c6d5f5fffb5a48e
https://pubmed.ncbi.nlm.nih.gov/18033811
https://pubmed.ncbi.nlm.nih.gov/18033811
Publikováno v:
The Journal of physiology. 580(Pt.3)
N-type calcium channels contribute to the release of glutamate from primary afferent terminals synapsing onto nocisponsive neurons in the dorsal horn of the spinal cord, but little is known of functional adaptations to these channels in persistent pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6a755c2a2cc13ebc370e48a657a5b926
https://pubmed.ncbi.nlm.nih.gov/17303639
https://pubmed.ncbi.nlm.nih.gov/17303639
Publisher Summary The most common application of the patch-clamp technique is to manipulate the cell membrane voltage and measure the electrical currents that flow across the membrane through ionic channels. Currents can be recorded either from indiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0322b66dca621a6ca0158b40d9a69788
https://doi.org/10.1016/b978-012164730-8/50049-6
https://doi.org/10.1016/b978-012164730-8/50049-6
Autor:
Beth K, Rycroft, Alasdair J, Gibb
Publikováno v:
The Journal of physiology. 557(Pt 3)
The NMDA receptor is modulated by changes in the intracellular calcium concentration, through activation of various intracellular calcium-dependent proteins. We have investigated regulation of single NMDA receptor channel activity by the calcium-sens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2e82c1aba61d4fac1dbd93795cbbb45c
https://pubmed.ncbi.nlm.nih.gov/15073274
https://pubmed.ncbi.nlm.nih.gov/15073274