Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Beth K Thielen"'
Autor:
Jessica K Fiege, Joshua M Thiede, Hezkiel Arya Nanda, William E Matchett, Patrick J Moore, Noe Rico Montanari, Beth K Thielen, Jerry Daniel, Emma Stanley, Ryan C Hunter, Vineet D Menachery, Steven S Shen, Tyler D Bold, Ryan A Langlois
Publikováno v:
PLoS Pathogens, Vol 17, Iss 1, p e1009292 (2021)
The human airway epithelium is the initial site of SARS-CoV-2 infection. We used flow cytometry and single cell RNA-sequencing to understand how the heterogeneity of this diverse cell population contributes to elements of viral tropism and pathogenes
Externí odkaz:
https://doaj.org/article/68102c0c4b2f4a7984aa55fb2d7b97a4
Autor:
Beth K Thielen, Kevin C Klein, Lorne W Walker, Mary Rieck, Jane H Buckner, Garrett W Tomblingson, Jaisri R Lingappa
Publikováno v:
PLoS Pathogens, Vol 3, Iss 9, Pp 1320-1334 (2007)
The deoxycytidine deaminase APOBEC3G (A3G) is expressed in human T cells and inhibits HIV-1 replication. When transfected into A3G-deficient epithelial cell lines, A3G induces catastrophic hypermutation by deaminating the HIV-1 genome. Interestingly,
Externí odkaz:
https://doaj.org/article/dd6a722cf18242ed8be0ae680893f899
Autor:
Vikram J. Christian, Raiya Sarwar, Joseph C. Resch, Sarah Lim, Arif Somani, Catherine Larson-Nath, Shane McAllister, Beth K. Thielen, Oyedele Adeyi, Srinath Chinnakotla, Heli Bhatt
Publikováno v:
Case Reports in Transplantation. 2022:1-5
Background. Since October 2021, there have been more than 500 cases of severe hepatitis of unknown origin in children reported worldwide, including 180 cases in the U.S. The most frequently detected potential pathogen to date has been adenovirus, typ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1bbe518559f48e7efe9a5e6550c3bfe
https://doi.org/10.1155/2022/9426175
https://doi.org/10.1155/2022/9426175
Publikováno v:
Open Forum Infectious Diseases. 9
Background Penicillin allergy is reported in approximately 10% of the US population and is one of the most frequent medication allergies in children. Penicillin allergy labels are associated with more expensive care and adverse outcomes, such as MRSA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d372b08011ce070cd7ee853fdd9903c5
https://doi.org/10.1093/ofid/ofac492.608
https://doi.org/10.1093/ofid/ofac492.608
320. Clinical Impact of Metagenomic Next Generation Sequencing in a Large Pediatric and Adult Cohort
Autor:
Alice Lehman, Lea Goren, Olivia Toles, Shannon L Andrews, Beth K Thielen, Daniel Drozdov, Nathan Rubin
Publikováno v:
Open Forum Infectious Diseases. 9
Background Plasma metagenomic next-generation sequencing (mNGS) is an emerging diagnostic tool. As the clinical use of mNGS increases, efforts to better understand the role of mNGS in diagnosis and management of infectious diseases are essential. Cur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef4c6bb2cdf84e93c3c96d4978c889ae
https://doi.org/10.1093/ofid/ofac492.398
https://doi.org/10.1093/ofid/ofac492.398
Autor:
Beth K Thielen, Jessica K. Fiege, Mari Shiratori, Clayton K. Mickelson, Ryan A. Langlois, Luis B. Barreiro, João Barroso-Batista, Haley E. Randolph
Publikováno v:
Science. 374:1127-1133
Humans differ in their susceptibility to infectious disease, partly owing to variation in the immune response after infection. We used single-cell RNA sequencing to quantify variation in the response to influenza infection in peripheral blood mononuc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6608071dbbf30ffa222fe23fb7d85e58
https://doi.org/10.1126/science.abg0928
https://doi.org/10.1126/science.abg0928
Autor:
Hey J Chong, Benjamin T Prince, Danielle E. Arnold, Kelli W. Williams, Wilfredo Cosme-Blanco, Margaret Redmond, Nicholas L. Hartog, Steven M. Holland, Beth K Thielen, Erinn S. Kellner
Publikováno v:
Pediatric Health, Medicine and Therapeutics. 11:257-268
Chronic granulomatous disease (CGD) is a rare but serious primary immunodeficiency with varying prevalence and rates of X-linked and autosomal recessive disease worldwide. Functional defects in the phagocyte nicotinamide adenine dinucleotide phosphat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83203cab73e63da2d8db5bc749257807
https://doi.org/10.2147/phmt.s254253
https://doi.org/10.2147/phmt.s254253
Autor:
Darlisha A. Williams, Katelyn A Pastick, Tyler D. Bold, Sarah M Lofgren, Lindsey Collins, Nicole Engen, David R. Boulware, Katherine Huppler Hullsiek, Caleb P Skipper, Ananta S Bangdiwala, Radha Rajasingham, Beth K Thielen, Margaret L Axelrod, Melanie R. Nicol, Elizabeth C Okafor, Matthew F Pullen, Alanna A Colette
Publikováno v:
Open Forum Infectious Diseases
Background During the Covid-19 pandemic, clinical trials necessitated rapid testing to be performed remotely. Dried blood spot (DBS) techniques have enabled remote HIV virologic testing globally and more recently, antibody testing as well. We evaluat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ea5fb21e91d597ad3a302068d10efd9
https://doi.org/10.1093/ofid/ofab506
https://doi.org/10.1093/ofid/ofab506
Antimalarial chemoprophylaxis and treatment in the USA: limited access and extreme price variability
Autor:
Beth K Thielen, Jonathan D. Alpern, Anne E. Frosch, Mackenzie L Smith, William M. Stauffer, Emily Walz, Danushka Wanduragala, Wilhelmina Holder, Ama Eli Boumi, Hannah R. Volkman
Publikováno v:
J Travel Med
To evaluate if cost and availability of antimalarials are barriers to malaria chemoprophylaxis and treatment, we surveyed retail pharmacies in Minneapolis/Saint Paul and New York City on the price and stocking of antimalarials. We demonstrated extrem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51edc8fe49bb58698d31cb63206b1b80
https://doi.org/10.1093/jtm/taab117
https://doi.org/10.1093/jtm/taab117
Autor:
Christopher J. Tignanelli, Sahar Lotfi-Emran, Rachel Morris, Beth K Thielen, Kristina Techar, Nicholas E. Ingraham, Shernan G. Holtan, R. Adams Dudley
Publikováno v:
The Lancet. Respiratory Medicine
The Lancet Respiratory Medicine
The Lancet Respiratory Medicine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d4c7b04b154a154ea444912298f3bec
https://doi.org/10.1016/s2213-2600(20)30226-5
https://doi.org/10.1016/s2213-2600(20)30226-5