Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Beth Goins"'
Autor:
Roslyn A Taylor, Sixia Xiao, Ann M Carias, Michael D McRaven, Divya N Thakkar, Mariluz Araínga, Edward J Allen, Kenneth A Rogers, Sidath C Kumarapperuma, Siqi Gong, Angela J Fought, Meegan R Anderson, Yanique Thomas, Jeffrey R Schneider, Beth Goins, Peter Fox, Francois J Villinger, Ruth M Ruprecht, Thomas J Hope
Publikováno v:
PLoS Pathogens, Vol 17, Iss 6, p e1009632 (2021)
Human immunodeficiency virus (HIV) vaccines have not been successful in clinical trials. Dimeric IgA (dIgA) in the form of secretory IgA is the most abundant antibody class in mucosal tissues, making dIgA a prime candidate for potential HIV vaccines.
Externí odkaz:
https://doaj.org/article/cc676bc5c0da4fd2ae31cd68f66412e3
Autor:
Sidath C. Kumarapperuma, Thomas J. Hope, Kenneth A. Rogers, Peter T. Fox, Edward J. Allen, Ruth M. Ruprecht, Mariluz Araínga, Francois Villinger, Yanique Thomas, Ann M. Carias, Meegan R. Anderson, Sixia Xiao, Jeffrey R. Schneider, Siqi Gong, Michael D. McRaven, Angela J. Fought, Roslyn A. Taylor, Beth Goins, Divya N. Thakkar
Publikováno v:
PLoS Pathogens, Vol 17, Iss 6, p e1009632 (2021)
PLoS Pathogens
PLoS Pathogens
Human immunodeficiency virus (HIV) vaccines have not been successful in clinical trials. Dimeric IgA (dIgA) in the form of secretory IgA is the most abundant antibody class in mucosal tissues, making dIgA a prime candidate for potential HIV vaccines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e15cb5f5661d494210cc2e8472676fd8
https://doaj.org/article/cc676bc5c0da4fd2ae31cd68f66412e3
https://doaj.org/article/cc676bc5c0da4fd2ae31cd68f66412e3
Autor:
Darrell J. Irvine, Torben Schiffner, Josetta Adams, Talar Tokatlian, Wei Zhang, Mariane B. Melo, William R. Schief, Crystal G. Franklin, Siqi Gong, Brittany L. Hartwell, Diane G. Carnathan, Ruth M. Ruprecht, Benjamin J. Cossette, Sergey Menis, Sidath C. Kumarapperuma, Guido Silvestri, Jacob T. Martin, Peter T. Fox, Beth Goins
Publikováno v:
Biomaterials
Elsevier
Elsevier
Antigen accumulation in lymph nodes (LNs) is critical for vaccine efficacy, but understanding of vaccine biodistribution in humans or large animals remains limited. Using the rhesus macaque model, we employed a combination of positron emission tomogr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a5c95baa91a5256fd8a0edfed9720ab
https://doi.org/10.1016/j.biomaterials.2021.120868
https://doi.org/10.1016/j.biomaterials.2021.120868
Publikováno v:
Journal of Applied Physiology. 103:28-38
Liposome-encapsulated Hb (LEH) is being developed as an artificially assembled, low-toxicity, and spatially isolated Hb-based oxygen carrier (HBOC). Standard methods of evaluating oxygen carriers are based on surrogate indicators of physiology in ani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed095fa5f91bc9341bbc8c13fd619186
https://doi.org/10.1152/japplphysiol.00136.2006
https://doi.org/10.1152/japplphysiol.00136.2006
Publikováno v:
International Journal of Pharmaceutics. 337:316-328
The goal of this study was to determine the distribution of the avidin/biotin-liposome system in an ovarian cancer xenograft model. Optimal avidin/biotin-liposome injection sequence with enhanced liposome accumulation to the peritoneum was determined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d84d55a0bb1fecc088050cbb8405fd43
https://doi.org/10.1016/j.ijpharm.2007.01.010
https://doi.org/10.1016/j.ijpharm.2007.01.010
Autor:
Arlan Richardson, Barry Grubbs, Asish R. Chaudhuri, Susan S. Padalecki, Eric de Waal, Yuji Ikeno, Brian Herman, Gregory R. Mundy, Beth Goins, Yingpei Zhang
Publikováno v:
Mechanisms of Ageing and Development. 128:213-221
Alteration of apoptotic activity has been observed in a number of tissues in aging mammals, but it remains unclear whether and/or how apoptosis may affect aging. Caspase-2 is a member of the cysteine protease family that plays a critical role in apop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f719655a45ca73362b3dd29ec0099dc
https://doi.org/10.1016/j.mad.2006.11.030
https://doi.org/10.1016/j.mad.2006.11.030
Autor:
Beth Goins, William T. Phillips, Paul A Jerabek, Yong Bradley, Linda M. McManus, Cristina Zavaleta
Publikováno v:
International Journal of Gynecologic Cancer. 17:407-417
MicroPET is a noninvasive imaging modality that can potentially track tumor development in nude rats using the radiotracer fluorine 18-fluorodeoxyglucose (18F-FDG). Our goal was to determine whether microPET, as opposed to more invasive techniques, c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0bd9743b6ae8530336e6d8eba47ff4c
https://doi.org/10.1111/j.1525-1438.2007.00814.x
https://doi.org/10.1111/j.1525-1438.2007.00814.x
Autor:
Sarmad Sabour, William T. Phillips, Beth Goins, Cristina Zavaleta, F. Ross Woolley, Xiangpeng Zheng, Randal A. Otto, Ande Bao, Mohan Natarajan
Publikováno v:
International Journal of Pharmaceutics. 316:162-169
Liposomes have recognized advantages as nano-particle drug carriers for tumor therapy. In this study, the pharmacokinetics and distribution of intratumorally administered liposomes were investigated as drug carriers for treating solid tumors via dire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::406dba59b170998ff053c26430e4a657
https://doi.org/10.1016/j.ijpharm.2006.02.039
https://doi.org/10.1016/j.ijpharm.2006.02.039
Autor:
William T. Phillips, Beth Goins, Xia Zhao, F. Ross Woolley, Ande Bao, Randal A. Otto, James M. Hevezi
Publikováno v:
Medical Physics. 32:200-208
Radioimmunotherapy of hematopoeitic cancers and micrometastases has been shown to have significant therapeutic benefit. The treatment of solid tumors with radionuclide therapy has been less successful. Previous investigations of intratumoral activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f527cea5ea9cfde50ce90c5aa2108d7
https://doi.org/10.1118/1.1833151
https://doi.org/10.1118/1.1833151
Publikováno v:
Journal of Pharmaceutical Sciences. 93:2595-2608
The objective of this study was to develop a more effective liposome-based method for delivering drugs to mediastinal nodes. Nodal uptake was determined after intrapleural injection of the avidin/biotin-liposome system in normal rats. The effect of i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06124a9f61ae5269bdca51b4441b7385
https://doi.org/10.1002/jps.20163
https://doi.org/10.1002/jps.20163