Single-cell RNA-seq profiling of mouse endothelial cells in response to pulmonary arterial hypertension

Autor: Peter Carmeliet, Robert Lafyatis, Mark Southwood, João P Monteiro, Katherine M Ross Stewart, Andrew H. Baker, Ana-Mishel Spiroski, Mairi Brittan, Jessica P. Scanlon, Neil C. Henderson, Paul D. Upton, Kevin Stewart, Shiau Haln Chen, Patrick W. F. Hadoke, Sweta Sweta, Ziwen Li, Alena Shmakova, Adam Handen, Stephen D Moore, Julie Rodor, Stephen Y. Chan, Axelle Caudrillier, Ross Dobie, Laura P.M.H. de Rooij, Beth Ep Henderson, Nicholas W. Morrell

Publikováno v: Rodor, J, Chen, S H, Scanlon, J P, Monteiro, J P, Caudrillier, A, Sweta, S, Ross Stewart, K, Shmakova, A, Dobie, R, Henderson, B EP, Stewart, K, Hadoke, P W F, Southwood, M, Moore, S D, Upton, P D, Morrell, N W, Li, Z, Chan, S Y, Handen, A, Lafyatis, R, de Rooij, L P M H, Henderson, N C, Carmeliet, P, Spiroski, A-M, Brittan, M & Baker, A H 2021, ' Single-cell RNA-seq profiling of mouse endothelial cells in response to pulmonary arterial hypertension ', Cardiovascular Research . https://doi.org/10.1093/cvr/cvab296

AimsEndothelial cell (EC) dysfunction drives the initiation and pathogenesis of pulmonary arterial hypertension (PAH). We aimed to characterize EC dynamics in PAH at single-cell resolution.Methods and resultsWe carried out single-cell RNA sequencing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::891a9d5ea79aa7f348c696c61724c06b
https://www.pure.ed.ac.uk/ws/files/227519929/cvab296.pdf