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Autor:
Avis R. Brennan, Marion Stanley, Mai-Anh T. Vu, Mark F. Yeckel, Beth Dolinsky, Amy F.T. Arnsten
Publikováno v:
Learning & Memory. 15:93-96
Planning and directing thought and behavior require the working memory (WM) functions of prefrontal cortex. WM is compromised by stress, which activates phosphatidylinositol (PI)-mediated IP3-PKC intracellular signaling. PKC overactivation impairs WM