Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Beth D. Jamieson"'
Autor:
Leila B. Giron, Qin Liu, Opeyemi S. Adeniji, Xiangfan Yin, Toshitha Kannan, Jianyi Ding, David Y. Lu, Susan Langan, Jinbing Zhang, Joao L. L. C. Azevedo, Shuk Hang Li, Sergei Shalygin, Parastoo Azadi, David B. Hanna, Igho Ofotokun, Jason Lazar, Margaret A. Fischl, Sabina Haberlen, Bernard Macatangay, Adaora A. Adimora, Beth D. Jamieson, Charles Rinaldo, Daniel Merenstein, Nadia R. Roan, Olaf Kutsch, Stephen Gange, Steven M. Wolinsky, Mallory D. Witt, Wendy S. Post, Andrew Kossenkov, Alan L. Landay, Ian Frank, Phyllis C. Tien, Robert Gross, Todd T. Brown, Mohamed Abdel-Mohsen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract People living with HIV (PLWH) experience increased vulnerability to premature aging and inflammation-associated comorbidities, even when HIV replication is suppressed by antiretroviral therapy (ART). However, the factors associated with this
Externí odkaz:
https://doaj.org/article/834ccc7d78f64593bd700f4fd920f417
Autor:
Joshua Zhang, Mary E. Sehl, Roger Shih, Elizabeth Crabb Breen, Fengxue Li, Ake T. Lu, Jay H. Bream, Priya Duggal, Jeremy Martinson, Steven M. Wolinsky, Otoniel Martinez-Maza, Christina M. Ramirez, Steve Horvath, Beth D. Jamieson
Publikováno v:
Frontiers in Bioinformatics, Vol 4 (2024)
Introduction: Highly active antiretroviral therapy (HAART) helps improve some measures of accelerated epigenetic aging in persons living with HIV (PLWH), but its overall impact on the epigenome is not fully understood.Methods: In this study, we analy
Externí odkaz:
https://doaj.org/article/b3905060df8f42c5b15b836f9f6b4669
Autor:
Mary E. Sehl, Elizabeth Crabb Breen, Roger Shih, Fengxue Li, Joshua Zhang, Peter Langfelder, Steve Horvath, Jay H. Bream, Priya Duggal, Jeremy Martinson, Steven M. Wolinsky, Otoniel Martinez-Maza, Christina M. Ramirez, Beth D. Jamieson
Publikováno v:
Frontiers in Bioinformatics, Vol 4 (2024)
IntroductionPersons living with HIV (PLWH) experience the early onset of age-related illnesses, even in the setting of successful human immunodeficiency virus (HIV) suppression with highly active antiretroviral therapy (HAART). HIV infection is assoc
Externí odkaz:
https://doaj.org/article/b9807aa06bea4118a72dfc77fba1c39e
Autor:
Elizabeth Crabb Breen, Mary E. Sehl, Roger Shih, Peter Langfelder, Ruibin Wang, Steve Horvath, Jay H. Bream, Priya Duggal, Jeremy Martinson, Steven M. Wolinsky, Otoniel Martínez-Maza, Christina M. Ramirez, Beth D. Jamieson
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107381- (2023)
Externí odkaz:
https://doaj.org/article/9ee0b81a978c4d8d81efed35a74145d8
Autor:
Najib Aziz, Roger Shih, Nicole Alexopoulos, Beth D. Jamieson, Matthew J. Mimiaga, Otoniel Martinez-Maza, Roger Detels
Publikováno v:
PLoS ONE, Vol 18, Iss 10 (2023)
Externí odkaz:
https://doaj.org/article/f40144ea943748928beff01ace3f429a
Autor:
Wenli Mu, Valerie Rezek, Heather Martin, Mayra A. Carrillo, Shallu Tomer, Philip Hamid, Miguel A. Lizarraga, Tristan D. Tibbe, Otto O. Yang, Beth D. Jamieson, Scott G. Kitchen, Anjie Zhen
Publikováno v:
JCI Insight, Vol 7, Iss 22 (2022)
A hallmark of HIV-1 infection is chronic inflammation, even in patients treated with antiretroviral therapy (ART). Chronic inflammation drives HIV-1 pathogenesis, leading to loss of CD4+ T cells and exhaustion of antiviral immunity. Therefore, strate
Externí odkaz:
https://doaj.org/article/ccbac288cbda4f758e65fea1428803d6
Autor:
Mary E. Sehl, Elizabeth Crabb Breen, Roger Shih, Larry Chen, Ruibin Wang, Steve Horvath, Jay H. Bream, Priya Duggal, Jeremy Martinson, Steven M. Wolinsky, Otoniel Martinez-Maza, Christina M. Ramirez, Beth D. Jamieson
Publikováno v:
Frontiers in Genetics, Vol 12 (2022)
Background: Epigenetic aging is accelerated in tissues of persons living with HIV (PLWH) and may underlie the early onset of age-related illnesses. This study examines the rate-of-change in epigenetic age in PLWH following HIV infection but before HA
Externí odkaz:
https://doaj.org/article/3899d6314e1a4354971179465b206a49
Autor:
Mary E. Sehl, Tammy M. Rickabaugh, Roger Shih, Otoniel Martinez-Maza, Steve Horvath, Christina M. Ramirez, Beth D. Jamieson
Publikováno v:
Pathogens and Immunity, Vol 5, Iss 1, Pp 291-311 (2020)
Background: HIV-1 infection is associated with acceleration of age-related methylation patterns in peripheral blood and brain of infected individuals although the relative contributions of HIV-1 infection versus its treatment to the observed accelera
Externí odkaz:
https://doaj.org/article/bca39c858722418d9a71064396d1d39e
Autor:
Dana Gabuzda, Beth D. Jamieson, Ronald G. Collman, Michael M. Lederman, Tricia H. Burdo, Steven G. Deeks, Dirk P. Dittmer, Howard S. Fox, Nicholas T. Funderburg, Savita G. Pahwa, Ivona Pandrea, Cara C. Wilson, Peter W. Hunt
Publikováno v:
Pathogens and Immunity, Vol 5, Iss 1, Pp 143-174 (2020)
People with HIV (PWH) experience accentuated biological aging, as defined by markers of inflammation, immune dysfunction, and the epigenetic clock. They also have an elevated risk of multiple age-associated comorbidities. To discuss current knowle
Externí odkaz:
https://doaj.org/article/67523edc367641d89c52c3931673c54e
Autor:
Kimberly Pelak, Anna C. Need, Jacques Fellay, Kevin V. Shianna, Sheng Feng, Thomas J. Urban, Dongliang Ge, Andrea De Luca, Javier Martinez-Picado, Steven M. Wolinsky, Jeremy J. Martinson, Beth D. Jamieson, Jay H. Bream, Maureen P. Martin, Persephone Borrow, Norman L. Letvin, Andrew J. McMichael, Barton F. Haynes, Amalio Telenti, Mary Carrington, David B. Goldstein, Galit Alter
Publikováno v:
PLoS Biology, Vol 9, Iss 12 (2011)
Externí odkaz:
https://doaj.org/article/217ee9a950054636b1c245ccb89b0265