Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Beth D. Herman"'
Publikováno v:
The Journal of Clinical Pharmacology. 43:423-427
The interaction between almotriptan, a 5-HT1B/1D agonist, and the potent CYP3A4 inhibitor ketoconazole was examined in 16 healthy volunteers. Subjects received (A) 12.5 mg almotriptan orally on Day 2 of a 3-day regimen of 400 mg ketoconazole once dai
Publikováno v:
Clinical Drug Investigation. 18:141-150
Objective: This study was performed to assess the tolerability of combined administration of reboxetine, a selective noradrenaline (norepinephrine) reuptake inhibitor, and fluoxetine, a selective serotonin reuptake inhibitor, relative to administrati
Publikováno v:
Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. 18:252-259
The potential pharmacokinetic drug-drug interaction between delavirdine, a nonnucleoside analogue reverse transcriptase inhibitor, and indinavir, an inhibitor of HIV protease, was evaluated in healthy volunteers. Subjects received a single 800-mg dos
Publikováno v:
Pharmaceutical Research. 11:1467-1473
The rate of hydrolysis of methylprednisolone sodium succinate in the freeze dried solid state at 40°C was determined in the presence of two common bulking agents - mannitol and lactose - at two different ratios of drug to excipient. Residual moistur
Publikováno v:
Clinical pharmacology and therapeutics. 70(3)
Objective The effect of reboxetine on electrocardiographic parameters, particularly the QTc interval, was assessed in 20 healthy subjects (15 male, 5 female). Methods In a 5-way crossover study, subjects received placebo, 2 mg, 4 mg, or 6 mg reboxeti