Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Beth D Jamieson"'
Autor:
Najib Aziz, Roger Shih, Nicole Alexopoulos, Beth D Jamieson, Matthew J Mimiaga, Otoniel Martinez-Maza, Roger Detels
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0290702 (2023)
IntroductionInterleukin 6 (IL-6) activates cells through its unique heterodimeric signaling complex of IL-6 receptor (IL6R) subunit and interleukin 6 signal transducer β-subunit glycoprotein 130 (gp130). The objective of this study was to investigat
Externí odkaz:
https://doaj.org/article/3f7aaca1d9bf4a749f98b734063aad07
Autor:
Jeffrey Dock, Christina M Ramirez, Lance Hultin, Mary Ann Hausner, Patricia Hultin, Julie Elliott, Otto O Yang, Peter A Anton, Beth D Jamieson, Rita B Effros
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182498 (2017)
A hallmark of human immunosenescence is the accumulation of late-differentiated memory CD8+ T cells with features of replicative senescence, such as inability to proliferate, absence of CD28 expression, shortened telomeres, loss of telomerase activit
Externí odkaz:
https://doaj.org/article/6bab4bfe0b8e4d8192471bd15f0484c3
Autor:
Leila B. Giron, Qin Liu, Opeyemi S. Adeniji, Xiangfan Yin, Toshitha Kannan, Jianyi Ding, David Y. Lu, Susan Langan, Jinbing Zhang, Joao L. L. C. Azevedo, Shuk Hang Li, Sergei Shalygin, Parastoo Azadi, David B. Hanna, Igho Ofotokun, Jason Lazar, Margaret A. Fischl, Sabina Haberlen, Bernard Macatangay, Adaora A. Adimora, Beth D. Jamieson, Charles Rinaldo, Daniel Merenstein, Nadia R. Roan, Olaf Kutsch, Stephen Gange, Steven M. Wolinsky, Mallory D. Witt, Wendy S. Post, Andrew Kossenkov, Alan L. Landay, Ian Frank, Phyllis C. Tien, Robert Gross, Todd T. Brown, Mohamed Abdel-Mohsen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract People living with HIV (PLWH) experience increased vulnerability to premature aging and inflammation-associated comorbidities, even when HIV replication is suppressed by antiretroviral therapy (ART). However, the factors associated with this
Externí odkaz:
https://doaj.org/article/834ccc7d78f64593bd700f4fd920f417
Autor:
Tammy M Rickabaugh, Ruth M Baxter, Mary Sehl, Janet S Sinsheimer, Patricia M Hultin, Lance E Hultin, Austin Quach, Otoniel Martínez-Maza, Steve Horvath, Eric Vilain, Beth D Jamieson
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119201 (2015)
Patients with treated HIV-1-infection experience earlier occurrence of aging-associated diseases, raising speculation that HIV-1-infection, or antiretroviral treatment, may accelerate aging. We recently described an age-related co-methylation module
Externí odkaz:
https://doaj.org/article/7558afab5b654c61821e3ab234b63001
Autor:
Otto O Yang, F Javier Ibarrondo, Charles Price, Lance E Hultin, Julie Elliott, Patricia M Hultin, Roger Shih, Mary Ann Hausner, Hwee L Ng, Jennifer Hoffman, Beth D Jamieson, Peter A Anton
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88621 (2014)
Mucosal immunity is central to sexual transmission and overall pathogenesis of HIV-1 infection, but the ability of vaccines to induce immune responses in mucosal tissue compartments is poorly defined. Because macaque vaccine studies suggest that ingu
Externí odkaz:
https://doaj.org/article/aabb0ec4ee86403e84bd97d2a892933e
Autor:
F Javier Ibarrondo, Otto O Yang, Thinle Chodon, Earl Avramis, Yohan Lee, Hooman Sazegar, Jason Jalil, Bartosz Chmielowski, Richard C Koya, Ingrid Schmid, Jesus Gomez-Navarro, Beth D Jamieson, Antoni Ribas, Begoña Comin-Anduix
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76829 (2013)
A significant barrier to effective immune clearance of cancer is loss of antitumor cytotoxic T cell activity. Antibodies to block pro-apoptotic/downmodulatory signals to T cells are currently being tested. Because invariant natural killer T cells (iN
Externí odkaz:
https://doaj.org/article/86bbe706996e4d22b7abc83500cf3d2b
Autor:
Kimberly Pelak, Anna C Need, Jacques Fellay, Kevin V Shianna, Sheng Feng, Thomas J Urban, Dongliang Ge, Andrea De Luca, Javier Martinez-Picado, Steven M Wolinsky, Jeremy J Martinson, Beth D Jamieson, Jay H Bream, Maureen P Martin, Persephone Borrow, Norman L Letvin, Andrew J McMichael, Barton F Haynes, Amalio Telenti, Mary Carrington, David B Goldstein, Galit Alter, NIAID Center for HIV/AIDS Vaccine Immunology
Publikováno v:
PLoS Biology, Vol 9, Iss 11, p e1001208 (2011)
A genome-wide screen for large structural variants showed that a copy number variant (CNV) in the region encoding killer cell immunoglobulin-like receptors (KIR) associates with HIV-1 control as measured by plasma viral load at set point in individua
Externí odkaz:
https://doaj.org/article/a88a6a17ab4c48cbaa44f406101588bf
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20781 (2011)
Individuals infected by HIV are at an increased risk for developing non-Hodgkin's lymphomas (AIDS-NHL). In the highly active antiretroviral therapy (HAART) era, there has been a significant decline in the incidence of AIDS-associated primary central
Externí odkaz:
https://doaj.org/article/2d495710f5634a2c9959245c14a03172
Autor:
Tammy M Rickabaugh, Ryan D Kilpatrick, Lance E Hultin, Patricia M Hultin, Mary Ann Hausner, Catherine A Sugar, Keri N Althoff, Joseph B Margolick, Charles R Rinaldo, Roger Detels, John Phair, Rita B Effros, Beth D Jamieson
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16459 (2011)
HIV-1-infected adults over the age of 50 years progress to AIDS more rapidly than adults in their twenties or thirties. In addition, HIV-1-infected individuals receiving antiretroviral therapy (ART) present with clinical diseases, such as various can
Externí odkaz:
https://doaj.org/article/67dec63e3462413aaeb356e676dd5eb4
Autor:
Joshua Zhang, Mary E. Sehl, Roger Shih, Elizabeth Crabb Breen, Fengxue Li, Ake T. Lu, Jay H. Bream, Priya Duggal, Jeremy Martinson, Steven M. Wolinsky, Otoniel Martinez-Maza, Christina M. Ramirez, Steve Horvath, Beth D. Jamieson
Publikováno v:
Frontiers in Bioinformatics, Vol 4 (2024)
Introduction: Highly active antiretroviral therapy (HAART) helps improve some measures of accelerated epigenetic aging in persons living with HIV (PLWH), but its overall impact on the epigenome is not fully understood.Methods: In this study, we analy
Externí odkaz:
https://doaj.org/article/b3905060df8f42c5b15b836f9f6b4669