Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Beth Chen"'
Autor:
Nicholas J. MacDonald, Kavita Singh, Karine Reiter, Vu Nguyen, Richard Shimp, Apostolos G. Gittis, Beth Chen, Martin Burkhardt, Baoshan Zhang, Zhixiong Wang, Raul Herrera, Mackenzie Moler, Duck-Yeon Lee, Sachy Orr-Gonzalez, Jessica Herrod, Lynn E. Lambert, Kelly M. Rausch, Olga Muratova, David S. Jones, Yimin Wu, Albert J. Jin, David N. Garboczi, Patrick E. Duffy, David L. Narum
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-9 (2023)
Abstract Development of a malaria vaccine that blocks transmission of different parasite stages to humans and mosquitoes is considered critical for elimination efforts. A vaccine using Pfs25, a protein on the surface of zygotes and ookinetes, is unde
Externí odkaz:
https://doaj.org/article/744dd43cb85546b1a8f8ee76086ef8c5
Autor:
Puthupparampil V. Scaria, Charles Anderson, Olga Muratova, Nada Alani, Hung V. Trinh, Steven T. Nadakal, Irfan Zaidi, Lynn Lambert, Zoltan Beck, Emma K. Barnafo, Kelly M. Rausch, Chris Rowe, Beth Chen, Gary R. Matyas, Mangala Rao, Carl R. Alving, David L. Narum, Patrick E. Duffy
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-10 (2021)
Abstract Malaria transmission-blocking vaccines candidates based on Pfs25 and Pfs230 have advanced to clinical studies. Exoprotein A (EPA) conjugate of Pfs25 in Alhydrogel® developed functional immunity in humans, with limited durability. Pfs230 con
Externí odkaz:
https://doaj.org/article/5f059d573321402aaaf06cc772fda055
Autor:
Puthupparampil V Scaria, Beth Chen, Christopher G Rowe, David S Jones, Emma Barnafo, Elizabeth R Fischer, Charles Anderson, Nicholas J MacDonald, Lynn Lambert, Kelly M Rausch, David L Narum, Patrick E Duffy
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0190312 (2017)
Chemical conjugation of polysaccharide to carrier proteins has been a successful strategy to generate potent vaccines against bacterial pathogens. We developed a similar approach for poorly immunogenic malaria protein antigens. Our lead candidates in
Externí odkaz:
https://doaj.org/article/2a694a1e2ca147cf9e3a3357db15e749
Autor:
David S Jones, Christopher G Rowe, Beth Chen, Karine Reiter, Kelly M Rausch, David L Narum, Yimin Wu, Patrick E Duffy
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0138761 (2016)
A practical method is described for synthesizing conjugated protein nanoparticles using thioether (thiol-maleimide) cross-linking chemistry. This method fills the need for a reliable and reproducible synthesis of protein conjugate vaccines for precli
Externí odkaz:
https://doaj.org/article/7ae623226dd943ff8db6cde05f050114
Development of a bivalent conjugate vaccine candidate against malaria transmission and typhoid fever
Autor:
Beth Chen, Emma Barnafo, Jae Seung Yang, Lynn Lambert, So Jung An, Patrick E. Duffy, Puthupparampil V. Scaria, Olga Muratova, Myung Hwa Chae, Charles Anderson
Publikováno v:
Vaccine. 36:2978-2984
Immune responses to poorly immunogenic antigens, such as polysaccharides, can be enhanced by conjugation to carriers. Our previous studies indicate that conjugation to Vi polysaccharide of Salmonella Typhi may also enhance immunogenicity of some prot
Autor:
Puthupparampil V. Scaria, Olga Muratova, Emma Barnafo, Elizabeth R. Fischer, Debbie D. Nahas, Lynn Lambert, Bob J. Lucas, Beth Chen, Christopher G. Rowe, David L. Narum, Patrick E. Duffy, Irfan Zaidi, Charles Anderson
Publikováno v:
NPJ Vaccines
npj Vaccines, Vol 4, Iss 1, Pp 1-10 (2019)
npj Vaccines, Vol 4, Iss 1, Pp 1-10 (2019)
Malaria transmission blocking vaccines (TBV) target the mosquito stage of parasite development by passive immunization of mosquitoes feeding on a vaccinated human. Through uptake of vaccine-induced antibodies in a blood meal, mosquito infection is ha
Autor:
Ravi, Prasad, Beth, Chen
Publikováno v:
Cancer treatment and research. 174
Imaging plays a multifaceted role in the diagnosis and characterization of head and neck oncological patients and is integral to their care. Given the complexity of treatment, a multimodality approach is often necessary. With the advent of new techno
Autor:
Ravi Prasad, Beth Chen
Publikováno v:
Cancer Treatment and Research ISBN: 9783319654201
Imaging plays a multifaceted role in the diagnosis and characterization of head and neck oncological patients and is integral to their care. Given the complexity of treatment, a multimodality approach is often necessary. With the advent of new techno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52456fa068b62aa532307e470fdf04bf
https://doi.org/10.1007/978-3-319-65421-8_5
https://doi.org/10.1007/978-3-319-65421-8_5
Autor:
David L. Narum, Elizabeth R. Fischer, Emma Barnafo, Kelly M. Rausch, David S. Jones, Lynn Lambert, Christopher G. Rowe, Beth Chen, Charles Anderson, Patrick E. Duffy, Nicholas J. MacDonald, Puthupparampil V. Scaria
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 12, p e0190312 (2017)
PLoS ONE, Vol 12, Iss 12, p e0190312 (2017)
Chemical conjugation of polysaccharide to carrier proteins has been a successful strategy to generate potent vaccines against bacterial pathogens. We developed a similar approach for poorly immunogenic malaria protein antigens. Our lead candidates in
Autor:
Niesha Griffith, Klaus Meier, Beth Chen, Debbie Wright, Rinku A. Patel, Barbara Vadnais, Robert Terkola, Rowena N. Schwartz, Maria José Tamés, Susan Goodin, Christian Doreau, Karen Chuk, Mikael Daouphars
Publikováno v:
Journal of Oncology Practice. 7:7-12
Although there has been a significant increase in the availability and use of oral chemotherapeutic agents, the guidelines around their safe handling are still evolving. Although oral chemotherapy is associated with ease of administration, it has the