Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Beth Ashbridge"'
Publikováno v:
Biology of Blood and Marrow Transplantation. 21:1334-1336
Cord blood (CB) leukocytes have inherent telomere length (TL) variation, and CB hematopoietic stem cells (HSC) can maintain high telomerase levels preventing telomere attrition in vitro. We evaluated TL changes in 13 adult double-unit CB transplant (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c553c5375be88ee394619d1c56495321
https://doi.org/10.1016/j.bbmt.2015.04.006
https://doi.org/10.1016/j.bbmt.2015.04.006
Autor:
Jacqueline Salit, Ronald G. Crystal, Beth Ashbridge, Ann E. Tilley, Timothy Wilson, Matthew S. Walters, Neil R. Hackett, Allison M. Rogalski, Lauren J. Buro-Auriemma, Malcolm A.S. Moore, Lindsay Lief, Jason G. Mezey, Robert J. Kaner, Bishnu P. De, Ben-Gary Harvey, Michelle R. Staudt
Publikováno v:
Respiratory Research
Background Aging involves multiple biologically complex processes characterized by a decline in cellular homeostasis over time leading to a loss and impairment of physiological integrity and function. Specific cellular hallmarks of aging include abno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79c17e6403d3276eae19aa7ccbfbeac9
https://doi.org/10.1186/s12931-014-0094-1
https://doi.org/10.1186/s12931-014-0094-1
Autor:
Vanessa Arbelaez, Michelle R. Staudt, Jonna Heldrich, Beth Ashbridge, Bi-Sen Ding, Matthew S. Walters, Malcolm A.S. Moore, Shahin Rafii, Ronald G. Crystal, Kazunori Gomi
Publikováno v:
Respiratory Research
Background As the multipotent progenitor population of the airway epithelium, human airway basal cells (BC) replenish the specialized differentiated cell populations of the mucociliated airway epithelium during physiological turnover and repair. Cult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f601d8a8b6584a6e090641d22386af47
https://doi.org/10.1186/1465-9921-14-135
https://doi.org/10.1186/1465-9921-14-135
Autor:
Deepak Koirala, Raphaël Rodriguez, Yuta Sannohe, Hiroshi Sugiyama, Soma Dhakal, Shankar Balasubramanian, Beth Ashbridge, Hanbin Mao
Ligands that stabilize the formation of telomeric DNA G-quadruplexes have potential as cancer treatments, because the G-quadruplex structure cannot be extended by telomerase, an enzyme over-expressed in many cancer cells. Understanding the kinetic, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fa6f07ae4a7ef4f0c3dfcf85fc5a7a5
https://europepmc.org/articles/PMC3277938/
https://europepmc.org/articles/PMC3277938/
We have used single-molecule fluorescence microscopy to study the folded state of human telomerase RNA (hTR). Here we show that hTR adopts a new conformation on binding to human telomerase reverse transcriptase (hTERT) and reconstitution of an active
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d930bf9b1dcda483d472708cb5640432
https://europepmc.org/articles/PMC3119468/
https://europepmc.org/articles/PMC3119468/
Publikováno v:
Blood. 120:4661-4661
Abstract 4661 Background: Umbilical cord blood (CB) is an alternative source of allogeneic hematopoietic stem cells for transplantation and has the advantage of a reduced stringency of the required human leukocyte antigen-match. It is limited, howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af13f7b184d8410fe8f900fbe313afe7
https://doi.org/10.1182/blood.v120.21.4661.4661
https://doi.org/10.1182/blood.v120.21.4661.4661