Zobrazeno 1 - 7 of 7 pro vyhledávání: '"Beth Ann Compton"'
1
Roles of the negatively charged N-terminal extension of Saccharomyces cerevisiae ribosomal protein S5 revealed by characterization of a yeast strain containing human ribosomal protein S5
Autor: Tatyana V. Pestova, Sujatha Gupta, William C. Merrick, Maria Hatzoglou, Terri Goss Kinzy, Beth Ann Compton, Christopher U.T. Hellen, Oleksandr Galkin, Amber A. Bentley, Anton A. Komar, Barsanjit Mazumder
Publikováno v: RNA. 13:2116-2128
Ribosomal protein (rp) S5 belongs to a family of ribosomal proteins that includes bacterial rpS7. rpS5 forms part of the exit (E) site on the 40S ribosomal subunit and is essential for yeast viability. Human rpS5 is 67% identical and 79% similar to S
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46f5c44cb871566e8867e55040e066ec
https://doi.org/10.1261/rna.688207
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2
The highly efficacious actions of N-desmethylclozapine at muscarinic receptors are unique and not a common property of either typical or atypical antipsychotic drugs: is M1 agonism a pre-requisite for mimicking clozapine?s actions?
Autor: Marilyn A. Davies, Sandra J. Hufeisen, Herbert Y. Meltzer, Beth Ann Compton-Toth, Bryan L. Roth
Publikováno v: Psychopharmacology. 178:451-460
Recent studies have suggested that the salutary actions of clozapine in schizophrenia may be due to selective activation of M(1) muscarinic receptors by clozapine and/or its major active metabolite N-desmethylclozapine.We systematically tested this h
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b66de053115e3a1b104c076acad6bf52
https://doi.org/10.1007/s00213-004-2017-1
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3
In Vitro Characterization of Ephedrine-Related Stereoisomers at Biogenic Amine Transporters and the Receptorome Reveals Selective Actions as Norepinephrine Transporter Substrates
Autor: Jon Birkes, Richard B. Rothman, Bryan L. Roth, Beth Ann Compton-Toth, John S. Partilla, Nga Vu, Richard A. Glennon, Sandra J. Hufeisen, Richard Young
Publikováno v: Journal of Pharmacology and Experimental Therapeutics. 307:138-145
Ephedrine is a long-studied stimulant available both as a prescription and over-the-counter medication, as well as an ingredient in widely marketed herbal preparations, and is also used as a precursor for the illicit synthesis of methamphetamine. Eph
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d73b5f935b6ee86ac214b66af576aed6
https://doi.org/10.1124/jpet.103.053975
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4
Identification of Two Serine Residues Essential for Agonist-Induced 5-HT2A Receptor Desensitization
Autor: Beth Ann Compton-Toth, John A. Gray, Bryan L. Roth
Publikováno v: Biochemistry. 42:10853-10862
5-HT(2A) serotonin receptors represent the principal molecular targets for LSD-like hallucinogens and atypical antipsychotic drugs. It has been proposed that a dysregulation of 5-HT(2A) receptor-mediated signaling may contribute to the pathogenesis o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fec12b0eb01e173871f8b3bc697ad9d1
https://doi.org/10.1021/bi035061z
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5
Preliminary report: Brain blood flow using PET in patients with posttraumatic stress disorder and substance-abuse histories
Autor: Evan D. Morris, Beverly Donovan, Marc S. Berridge, Dennis Nelson, Peter F. Goyer, Floro Miraldi, G. J. Muswick, Greg Leisure, Richard A. McCormick, S. Charles Schulz, Beth Ann Compton, William E. Semple
Publikováno v: Biological Psychiatry. 34:115-118
Posttraumatic stress disorder (PTSD) is defined by DSM-III-R as an anxiety disorder characterized by recurrent distressing and intrusive remembrances of a traumatic event (American Psychiatric Association 1987). Some physiological abnormalities have
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8df62f7d8ce582726226febe16382195
https://doi.org/10.1016/0006-3223(93)90264-e
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6
A direct interaction of PSD-95 with 5-HT2A serotonin receptors regulates receptor trafficking and signal transduction
Autor: John A. Gray, Zongqi Xia, Beth Ann Compton-Toth, Bryan L. Roth
Publikováno v: The Journal of biological chemistry, vol 278, iss 24
Xia, Z; Gray, JA; Compton-Toth, BA; & Roth, BL. (2003). A direct interaction of PSD-95 with 5-HT2A serotonin receptors regulates receptor trafficking and signal transduction. Journal of Biological Chemistry, 278(24), 21901-21908. doi: 10.1074/jbc.M301905200. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/33h6t938
The serotonin (5-hydroxytryptamine) 2A receptor (5-HT2A) is an important G protein-coupled receptor (GPCR) that mediates the effects of hallucinogens and is the target of a number of commonly prescribed medications including atypical antipsychotics,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac6a71b139b8cfdde872191379a3d912
https://escholarship.org/uc/item/33h6t938
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