Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Beth A. Lee"'
Autor:
Amy Tasca, Kristina Astleford, Ari Lederman, Eric D. Jensen, Beth S. Lee, Rajaram Gopalakrishnan, Kim C. Mansky
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Osteoclasts begin as mononuclear cells that fuse to form multinuclear cells able to resorb bone. The mechanisms that regulate all the steps of osteoclast differentiation are not entirely known. MYO10, an unconventional myosin, has previously
Externí odkaz:
https://doaj.org/article/cec4fadd19f14b0895c4665d05c0fb52
Autor:
Richard T. Clements, Radmila Terentyeva, Shanna Hamilton, Paul M. L. Janssen, Karim Roder, Benjamin Y. Martin, Fruzsina Perger, Timothy Schneider, Zuzana Nichtova, Anindhya S. Das, Roland Veress, Beth S. Lee, Do-Gyoon Kim, Gideon Koren, Matthew S. Stratton, Gyorgy Csordas, Federica Accornero, Andriy E. Belevych, Sandor Gyorke, Dmitry Terentyev
Publikováno v:
Basic Research in Cardiology. 118
Calcium transfer into the mitochondrial matrix during sarcoplasmic reticulum (SR) Ca2+ release is essential to boost energy production in ventricular cardiomyocytes (VCMs) and match increased metabolic demand. Mitochondria from female hearts exhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbc16c7193cf2b8cedadcf67efa7dafc
https://doi.org/10.1007/s00395-023-00988-1
https://doi.org/10.1007/s00395-023-00988-1
Autor:
Jeremy W. Luk, Bethany L. Stangl, Tommy Gunawan, Melanie L. Schwandt, James K. Morris, Jared C. Axelowitz, Sumedha Chawla, Beth A. Lee, Megan Carraco, Sheila Walsh, Christian McDuffie, Khushbu Agarwal, Paule V. Joseph, Reza Momenan, David Goldman, Nancy Diazgranados, Vijay A. Ramchandani
Publikováno v:
The Journal of Clinical Psychiatry. 84
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ba8a5ea9745d1ff3ac2c56dd67074dc
https://doi.org/10.4088/jcp.22br14462
https://doi.org/10.4088/jcp.22br14462
Autor:
Emily L. Durham, Zachary J. Grey, Laurel Black, R. Nicole Howie, Jeremy L. Barth, Beth S. Lee, James J. Cray
Publikováno v:
Life sciences. 311
Evidence suggests alterations of thyroid hormone levels can disrupt normal bone development. Most data suggest the major targets of thyroid hormones to be the Htra1/Igf1 pathway. Recent discovery by our group suggests involvement of targets WNT pathw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0db9caa0ab42db702638f41de787c438
https://pubmed.ncbi.nlm.nih.gov/36370870
https://pubmed.ncbi.nlm.nih.gov/36370870
Autor:
Suman Govindaraju, Beth S. Lee
Publikováno v:
Cellular Physiology and Biochemistry, Vol 34, Iss 2, Pp 519-532 (2014)
Background/Aims: HuR is an RNA-binding protein that regulates the post-transcriptional life of thousands of cellular mRNAs and promotes cell survival. HuR is expressed as two mRNA transcripts that are differentially regulated by cell stress. The goal
Externí odkaz:
https://doaj.org/article/c9dd86ea43c5497d8bafa61fec77468f
Autor:
Beth S. Lee
Publikováno v:
Biomolecules, Vol 8, Iss 4, p 157 (2018)
Skeletal quantity and quality are determined by processes of bone modeling and remodeling, which are undertaken by cells that build and resorb bone as they respond to mechanical, hormonal, and other external and internal signals. As the sole bone res
Externí odkaz:
https://doaj.org/article/d243d1a50a3e4655831c49a57532b4c1
Publikováno v:
Bone. 163:116501
One-third of postmenopausal women experience at least one osteoporotic bone fracture in their lifetime that occurs spontaneously or from low-impact events. However, osteoporosis-associated jaw bone fractures are extremely rare. It was also observed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d449507aa29b3775ddc92dac3fcd18d
https://doi.org/10.1016/j.bone.2022.116501
https://doi.org/10.1016/j.bone.2022.116501
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87402 (2014)
Osteoclasts are large, multinucleated cells of the monocyte-macrophage lineage that generate specialized substrate adhesion complexes to facilitate their function as bone-degrading cells. The patterning and function of these actin-based complexes, po
Externí odkaz:
https://doaj.org/article/a64e5b61cc134caea953b2dcc20d98be
Autor:
Do-Gyoon Kim, Beth S. Lee, Toru Deguchi, Hongsik Cho, Anastasios Karydis, Fazal Ur Rehman Bhatti
Publikováno v:
Current osteoporosis reportsPapers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance. 19(2)
Many mechanical load-bearing joints of the body are prone to posttraumatic osteoarthritis (PTOA), including the knee joint and temporomandibular joint (TMJ). Early detection of PTOA can be beneficial in prevention or alleviating further progression o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d10839a574f1489b25d6962e9e5451a
https://pubmed.ncbi.nlm.nih.gov/33523424
https://pubmed.ncbi.nlm.nih.gov/33523424
Publikováno v:
J Biomech
Estrogen deficiency activates bone resorbing cells (osteoclasts) and to a lesser extent bone forming cells (osteoblasts), resulting in a gap between resorption and formation that leads to a net loss of bone. These cell activities alter bone architect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8f1ca11e76f79512d687d333ec2c38b
https://pubmed.ncbi.nlm.nih.gov/33915473
https://pubmed.ncbi.nlm.nih.gov/33915473