Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Beth A. Langdon"'
Autor:
Daniel O. Blackwood, Mark A. Polizzi, Lauren Beach, Rajesh N. Dave, Matthew P. Mullarney, Beth A. Langdon
Publikováno v:
Powder Technology. 212:397-402
A method for applying nano-sized silicon dioxide guest particles onto host pharmaceutical particles (a.k.a. “dry-coating” or “nanocoating”) has been developed using conventional pharmaceutical processing equipment. It has been demonstrated th
Publikováno v:
International Journal of Pharmaceutics. 241:73-85
Purpose: To better understand the influence of long-range molecular order on the processing characteristics of an active pharmaceutical ingredient (API). Methods: Crystalline and amorphous samples of a model drug substance were isolated and their “
Publikováno v:
Journal of Pharmacy and Pharmacology. 53:1193-1199
The powder flow and compact mechanical properties of two recently developed matrix-forming polymers were determined. The polymers are cross-linked high-amylose starch (Contramid) and poly(acrylic acid) (Carbopol EX507), and their properties were comp
Autor:
Anil Kane, Kam Agarwal, Lalji Kathiria, Ian Hicks, Beth A. Langdon, Fasheng Li, Daniel Song, Gautam Ramchandra Ranade, Joseph Kushner
Publikováno v:
Journal of pharmaceutical sciences. 103(2)
The impact of filler-lubricant particle size ratio variation (3.4-41.6) on the attributes of an immediate-release tablet was compared with the impacts of the manufacturing method used (direct compression or dry granulation) and drug loading (1%, 5%,
Publikováno v:
Journal of pharmaceutical sciences. 100(6)
A quality-by-design study examining the impact of variability in excipient material properties on the quality attributes of an immediate release tablet was performed. A literature review and risk analysis identified particle size of microcrystalline
Publikováno v:
International journal of pharmaceutics. 257(1-2)
The physical, flow, and mechanical properties of four common pharmaceutical sweeteners were measured to assess their relative manufacturability in solid dosage formulations. Sucrose, acesulfame potassium (Sunett), saccharin sodium, and aspartame were
Autor:
Dauda D. Ladipo, R. E. Link, Beth A. Langdon, M. R. Mitchell, Bruno C. Hancock, Glenn T. Carlson, Matthew P. Mullarney, Kim E. Vukovinsky
Publikováno v:
Journal of Testing and Evaluation. 37:102109
Indentation measurements are commonly used to determine the mechanical properties of pharmaceutical compacts. Specifically, they are used to assess their resistance to plastic deformation and to help predict tablet properties. To date there has been