Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Beth A. Habecker"'
Autor:
Joseph J. Sepe, PhD, Ryan T. Gardner, PhD, Matthew R. Blake, BS, Deja M. Brooks, BS, Melanie A. Staffenson, BS, Courtney B. Betts, PhD, Sam Sivagnanam, MS, William Larson, BS, Sushil Kumar, PhD, Richard G. Bayles, PhD, Haihong Jin, PhD, Michael S. Cohen, PhD, Lisa M. Coussens, PhD, Beth A. Habecker, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 7, Iss 9, Pp 915-930 (2022)
Summary: Myocardial infarction (MI) triggers an inflammatory response that transitions from pro-inflammatory to reparative over time. Restoring sympathetic nerves in the heart after MI prevents arrhythmias. This study investigated if reinnervation al
Externí odkaz:
https://doaj.org/article/e9c3ebef13134e50a3813ff599fa7eea
Autor:
Matthew R. Blake, Diana C. Parrish, Melanie A. Staffenson, Morgan A. Johnson, William R. Woodward, Beth A. Habecker
Publikováno v:
Physiological Reports, Vol 11, Iss 10, Pp n/a-n/a (2023)
Abstract Sympathetic nerve loss in the heart predicts the risk of ventricular arrhythmias after myocardial infarction (MI) in patients. Sympathetic denervation after cardiac ischemia–reperfusion is sustained by matrix components chondroitin sulfate
Externí odkaz:
https://doaj.org/article/83cf20394cee4635ad930908995393d8
Autor:
Annalise N. vonderEmbse, Sarah E. Elmore, Kyle B. Jackson, Beth A. Habecker, Katherine E. Manz, Kurt D. Pennell, Pamela J. Lein, Michele A. La Merrill
Publikováno v:
Environmental Health, Vol 20, Iss 1, Pp 1-16 (2021)
Abstract Background Exposure to the bioaccumulative pesticide dichlorodiphenyltrichloroethane (DDT) and its metabolite dichlorodiphenyldichloroethylene (DDE) has been associated with increased risk of insulin resistance and obesity in humans and expe
Externí odkaz:
https://doaj.org/article/5b7e36c61c2f4a7ea34b66c4dd6dc53d
Publikováno v:
Physiological Reports, Vol 10, Iss 10, Pp n/a-n/a (2022)
Abstract Sympathetic neurons that innervate the heart are located primarily in the stellate ganglia (SG), which also contains neurons that project to brown adipose tissue (BAT). These studies were designed to examine the morphology of these two popul
Externí odkaz:
https://doaj.org/article/c4001579efdb4538b206aa9a4a206dfd
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
The sympathetic nervous system plays a critical role in regulating many autonomic functions, including cardiac rhythm. The postganglionic neurons in the sympathetic chain ganglia are essential components that relay sympathetic signals to target tissu
Externí odkaz:
https://doaj.org/article/570834c9fd8b4bb187b464ee93dfe4a6
Publikováno v:
Physiological Reports, Vol 9, Iss 22, Pp n/a-n/a (2021)
Abstract Variants in the LMNA gene, which encodes for Lamin A/C, are associated with cardiac conduction disease (CCD). We previously reported that Lamin A/C variants p.R545H and p.A287Lfs*193, which were identified in CCD patients, decreased peak INa
Externí odkaz:
https://doaj.org/article/7aaf40cbff3446268244b82cff02bd1c
Publikováno v:
BMC Research Notes, Vol 11, Iss 1, Pp 1-6 (2018)
Abstract Objective Norepinephrine (NE), a sympathetic neurotransmitter, is often measured in plasma as an index of sympathetic activity. To better understand NE dynamics, it is important to measure its principal metabolite, 3,4-dihydroxyphenylglycol
Externí odkaz:
https://doaj.org/article/0b169723d7014782b1e647d38e36c144
Autor:
Shannon R. Murphy, Lianguo Wang, Zhen Wang, Philip Domondon, Di Lang, Beth A. Habecker, Rachel C. Myles, Crystal M. Ripplinger
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
β-adrenergic receptor (β-AR) blockers may be administered during acute myocardial infarction (MI), as they reduce energy demand through negative chronotropic and inotropic effects and prevent ischemia-induced arrhythmogenesis. However, the direct e
Externí odkaz:
https://doaj.org/article/ea43457716d342fc95f69a5723aa6417
Autor:
Matthew R Blake, Diana C Parrish, Melanie A Staffenson, Shanice Sueda, William R Woodward, Beth A Habecker
Publikováno v:
eLife, Vol 11 (2022)
Sympathetic denervation of the heart following ischemia/reperfusion induced myocardial infarction (MI) is sustained by chondroitin sulfate proteoglycans (CSPGs) in the cardiac scar. Denervation predicts risk of sudden cardiac death in humans. Blockin
Externí odkaz:
https://doaj.org/article/d6ecbe0551b6479984c4b2b438b21fc2
Publikováno v:
The Journal of Physiology. 601:1247-1264
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf1c13b7a2478aa298ee8f66474365fa
https://doi.org/10.1113/jp284059
https://doi.org/10.1113/jp284059