Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Beth A Sundberg"'
Autor:
John P Sundberg, C Herbert Pratt, Leslie P Goodwin, Kathleen A Silva, Victoria E Kennedy, Christopher S Potter, Anisa Dunham, Beth A Sundberg, Harm HogenEsch
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0235295 (2020)
Spontaneous mutations in the SHANK-associated RH domain interacting protein (Sharpin) resulted in a severe autoinflammatory type of chronic proliferative dermatitis, inflammation in other organs, and lymphoid organ defects. To determine whether cell-
Externí odkaz:
https://doaj.org/article/29c43fb89abe4d078f355f40d44e7a05
Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program.
Autor:
John P Sundberg, Soheil S Dadras, Kathleen A Silva, Victoria E Kennedy, Gaven Garland, Stephen A Murray, Beth A Sundberg, Paul N Schofield, C Herbert Pratt
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180682 (2017)
The International Knockout Mouse Consortium was formed in 2007 to inactivate ("knockout") all protein-coding genes in the mouse genome in embryonic stem cells. Production and characterization of these mice, now underway, has generated and phenotyped
Externí odkaz:
https://doaj.org/article/9f38595f5cf14dd1a56dbfcda9d20c9b
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
Data are increasingly annotated with multiple ontologies to capture rich information about the features of the subject under investigation. Analysis may be performed over each ontology separately, but, recently, there has been a move to combine multi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::497c7ac3696d5870f860729575ecbad6
http://link.springer.com/article/10.1038/s41598-019-40368-1
http://link.springer.com/article/10.1038/s41598-019-40368-1
Autor:
Harm HogenEsch, Kathleen A. Silva, C. Herbert Pratt, Victoria E. Kennedy, John P. Sundberg, Anisa Dunham, Leslie P. Goodwin, Christopher S. Potter, Beth A. Sundberg
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 7, p e0235295 (2020)
PLoS ONE, Vol 15, Iss 7, p e0235295 (2020)
Spontaneous mutations in the SHANK-associated RH domain interacting protein (Sharpin) resulted in a severe autoinflammatory type of chronic proliferative dermatitis, inflammation in other organs, and lymphoid organ defects. To determine whether cell-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42d6d5fa80906022db7a58f2db63e2de
http://europepmc.org/articles/PMC7371178
http://europepmc.org/articles/PMC7371178
Autor:
Sarah C. Linn, Kathleen A. Silva, Lesley S Bechtold, Allison Mustonen, Paul N. Schofield, John P. Sundberg, Robert Hoehndorf, Sarah M. Alghamdi, Victoria E. Kennedy, Beth A. Sundberg
Publikováno v:
Experimental Dermatology. 28:383-390
In a large-scale ageing study, 30 inbred mouse strains were systematically screened for histologic evidence of lesions in all organ systems. Ten strains were diagnosed with similar nail abnormalities. The highest frequency was noted in NON/ShiLtJ mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed224f1f78fd40e3d06b0cf9ab9d69c5
https://doi.org/10.1111/exd.13759
https://doi.org/10.1111/exd.13759
Autor:
Victoria E. Kennedy, Beth A. Sundberg, John J Wilson, Kathleen A. Silva, Derry C. Roopenian, John P. Sundberg, Nicholas E. Gott
Publikováno v:
Experimental Dermatology. 28:1091-1093
2-deoxy D-glucose (2DG) was tested for efficacy in treating alopecia areata using the C3H/HeJ skin graft model. 2DG has proven to be efficacious in treatment of various mouse models of autoimmunity with minimal serious side effects noted. This agent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::752fed0ae4dcdd913262b3f0d6fa3f90
https://doi.org/10.1111/exd.14008
https://doi.org/10.1111/exd.14008
Autor:
Beth A. Sundberg, Qiaoli Li, Michael V. Wiles, Benjamin L. King, Vivek M. Philip, Tim Stearns, Benjamin E. Low, John P. Sundberg, Jouni Uitto, Amir Hossein Saeidian, Jason A. Bubier
Publikováno v:
J Invest Dermatol
Pseudoxanthoma elasticum, a prototype of heritable multisystem ectopic mineralization disorders, is caused by mutations in the ABCC6 gene encoding a putative efflux transporter, ABCC6. The phenotypic spectrum of pseudoxanthoma elasticum varies, and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d570a116fb8ec80b683b99a249c1e738
https://europepmc.org/articles/PMC6874750/
https://europepmc.org/articles/PMC6874750/
Autor:
Anne M. Bowcock, Wenning Qin, C. Herbert Pratt, John P. Sundberg, Jacqueline Frost, Tim Stearns, Victoria E. Kennedy, Kathleen A. Silva, Beth A. Sundberg
Publikováno v:
Exp Mol Pathol
Psoriasis (PS) is a common inflammatory and incurable skin disease affecting 2–3% of the human population. Although genome-wide association studies implicate more than 60 loci, the full complement of genetic factors leading to disease is not known.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1110d1218b37a2c70b8b9f12fdb9d989
https://pubmed.ncbi.nlm.nih.gov/31323190
https://pubmed.ncbi.nlm.nih.gov/31323190
Autor:
Paul N. Schofield, Cheryl L. Ackert-Bicknell, Annerose Berndt, Kathleen A. Silva, Justin M M Cates, John P. Sundberg, Victoria E. Kennedy, Beth A. Sundberg
Publikováno v:
Experimental and Molecular Pathology. 100:92-100
Fibro-osseous lesions in mice are progressive aging changes in which the bone marrow is replaced to various degrees by fibrovascular stroma and bony trabeculae in a wide variety of bones. The frequency and severity varied greatly among 28 different i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90dae4972673d00d65ac61d1459033e7
https://doi.org/10.1016/j.yexmp.2015.11.018
https://doi.org/10.1016/j.yexmp.2015.11.018
Autor:
M A Richardson, Jouni Uitto, Roderick T. Bronson, Beth A. Sundberg, Qiaoli Li, John P. Sundberg, Annerose Berndt, Kathleen A. Silva, Victoria E. Kennedy
Publikováno v:
Veterinary Pathology. 51:846-857
Detailed histopathological diagnoses of inbred mouse strains are important for interpreting research results and defining novel models of human diseases. The aim of this study was to histologically detect lesions affecting the KK/HlJ inbred strain. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::853123f4e4b37c5952b7867367ae4450
https://doi.org/10.1177/0300985813501335
https://doi.org/10.1177/0300985813501335