Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Beth Beaudet"'
Autor:
Robert T Jacobs, Bakela Nare, Stephen A Wring, Matthew D Orr, Daitao Chen, Jessica M Sligar, Matthew X Jenks, Robert A Noe, Tana S Bowling, Luke T Mercer, Cindy Rewerts, Eric Gaukel, Jennifer Owens, Robin Parham, Ryan Randolph, Beth Beaudet, Cyrus J Bacchi, Nigel Yarlett, Jacob J Plattner, Yvonne Freund, Charles Ding, Tsutomu Akama, Y-K Zhang, Reto Brun, Marcel Kaiser, Ivan Scandale, Robert Don
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 5, Iss 6, p e1151 (2011)
BACKGROUND: Human African trypanosomiasis (HAT) is an important public health problem in sub-Saharan Africa, affecting hundreds of thousands of individuals. An urgent need exists for the discovery and development of new, safe, and effective drugs to
Externí odkaz:
https://doaj.org/article/63cd3700496b42e79618890a16e02bc3
Autor:
Cindy Rewerts, Robert T. Jacobs, Jacob Platner, Cyrus J. Bacchi, Robert Don, Beth Beaudet, Robin Parham, Stephen A. Wring, Nigel Yarlett, Luke Mercer, Ryan Randolph, Eric Gaukel, Bakela Nare, Tana Bowling
Publikováno v:
Parasitology
SUMMARYThis review presents a progression strategy for the discovery of new anti-parasitic drugs that uses in vitro susceptibility, time-kill and reversibility measures to define the therapeutically relevant exposure required in target tissues of ani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25a6d21bbbb97ea9a0b2f6c31729feac
http://doc.rero.ch/record/289976/files/S003118201300098X.pdf
http://doc.rero.ch/record/289976/files/S003118201300098X.pdf
Autor:
Diane M. Ignar, Jason D. Speake, Yuping Gong, Zhiyang Zhao, Beth Beaudet, Jeffrey P. Krise, Melanie N. Tallman, Donavon J. McConn
Publikováno v:
Pharmaceutical Research. 24:1138-1144
A series of melanocortin-4 receptor (MC4R) agonists, developed for use as anti-obesity agents, were found to have unusual pharmacokinetic behavior arising from excessive retention in the liver, with nearly undetectable levels in plasma following oral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fa6df8b2f425ed6d0ec5f10390efbe0
https://doi.org/10.1007/s11095-007-9239-y
https://doi.org/10.1007/s11095-007-9239-y
SCYX-7158, an orally-active benzoxaborole for the treatment of stage 2 human African trypanosomiasis
Autor:
Reto Brun, Cindy Rewerts, Beth Beaudet, Daitao Chen, Yvonne Freund, Robin Parham, Marcel Kaiser, Eric Gaukel, Robert T. Jacobs, Tana Bowling, Jessica M. Sligar, Matthew Jenks, Yong Kang Zhang, Robert Don, Robert A. Noe, Matthew D. Orr, Jennifer Owens, Cyrus J. Bacchi, Charles Z. Ding, Ivan Scandale, Luke Mercer, Jacob J. Plattner, Stephen A. Wring, Nigel Yarlett, Tsutomu Akama, Ryan Randolph, Bakela Nare
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 5, Iss 6, p e1151 (2011)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Background Human African trypanosomiasis (HAT) is an important public health problem in sub-Saharan Africa, affecting hundreds of thousands of individuals. An urgent need exists for the discovery and development of new, safe, and effective drugs to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a589b21f6358a2d00144a11912e5efd6
http://europepmc.org/articles/PMC3125149?pdf=render
http://europepmc.org/articles/PMC3125149?pdf=render
Autor:
Yuping Gong, Donavon McConn, Beth Beaudet, Melanie Tallman, Jason Speake, Diane Ignar, Jeffrey Krise
Publikováno v:
Pharmaceutical Research; Jun2007, Vol. 24 Issue 6, p1138-1144, 7p