Editorial: Beclin 1 and autophagy---in memory of Beth Levine (1960-2020).

Autor: Xu H; Department of Pharmacology and Laboratory of Aging and Nervous Diseases, Jiangsu Key Laboratory of Neuropsychiatric Diseases, College of Pharmaceutical Sciences, Soochow University, Suzhou, China., Qin ZH; Department of Pharmacology and Laboratory of Aging and Nervous Diseases, Jiangsu Key Laboratory of Neuropsychiatric Diseases, College of Pharmaceutical Sciences, Soochow University, Suzhou, China., Wei Y; Cancer Hospital and Research Institute, Guangzhou Medical University, Guangzhou, China., Wu J; Department of Pharmacology and Laboratory of Aging and Nervous Diseases, Jiangsu Key Laboratory of Neuropsychiatric Diseases, College of Pharmaceutical Sciences, Soochow University, Suzhou, China.

Publikováno v: Frontiers in cell and developmental biology [Front Cell Dev Biol] 2022 Oct 24; Vol. 10, pp. 1058861. Date of Electronic Publication: 2022 Oct 24 (Print Publication: 2022).

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Remembering Beth Levine – the autophagy pioneer and woman extraordinaire

Autor: Sophie Pattingre, Alicia Meléndez, Congcong He, Salwa Sebti, J. Marie Hardwick, Diane E. Griffin, Ana Maria Cuervo

Publikováno v: The FEBS Journal. 287:4314-4321

Beth Levine was a remarkable scientist who launched the burgeoning field of autophagy. The biological process of autophagy was beginning to gain attention through new genetic studies in yeast when Beth Levine's transformative work on the genetics of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::febdc9cad1b4b1c5f4da446a839af4a2
https://doi.org/10.1111/febs.15502

GRB2 is a BECN1 interacting protein that regulates autophagy

Autor: Jetsy Montero-Vergara, Kira Plachetta, Lisa Kinch, Stephan Bernhardt, Kriti Kashyap, Beth Levine, Lipi Thukral, Martina Vetter, Christoph Thomssen, Stefan Wiemann, Samuel Peña-Llopis, Verena Jendrossek, Silvia Vega-Rubin-de-Celis

Publikováno v: Cell Death and Disease, Vol 15, Iss 1, Pp 1-11 (2024)

Abstract GRB2 is an adaptor protein of HER2 (and several other tyrosine kinases), which we identified as a novel BECN1 (Beclin 1) interacting partner. GRB2 co-immunoprecipitated with BECN1 in several breast cancer cell lines and regulates autophagy t

Externí odkaz: https://doaj.org/article/762fefe82a1e46f087b2a5cf64ad3261