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of 1 572
pro vyhledávání: '"Beta-cell dysfunction"'
Autor:
Gyan Watson Ray, Qiaoli Zeng, Phidelia Kusi, Hengli Zhang, Taotao Shao, Taili Yang, Yue Wei, Mianqin Li, Xiaoqun Che, Runmin Guo
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Gestational diabetes mellitus (GDM) poses a significant global health concern, impacting both maternal and fetal well-being. Early detection and treatment are imperative to mitigate adverse outcomes during pregnancy. This review delves into the pivot
Externí odkaz:
https://doaj.org/article/eaeac92341384518b3ce99f04058b16d
Publikováno v:
Endocrinology and Metabolism, Vol 38, Iss 5, Pp 482-492 (2023)
This review explores the potential benefits of taurine in ameliorating the metabolic disorders of obesity and type 2 diabetes (T2D), highlighting the factors that bridge these associations. Relevant articles and studies were reviewed to conduct a com
Externí odkaz:
https://doaj.org/article/508f6d71172646ab98cfba384dc68eb2
Autor:
Cham Jazieh, Tarek Ziad Arabi, Zohaib Asim, Belal Nedal Sabbah, Aljohara Waleed Alsaud, Khaled Alkattan, Ahmed Yaqinuddin
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Type 2 diabetes mellitus (T2DM) is a rapidly escalating global health concern, with its prevalence projected to increase significantly in the near future. This review delves into the intricate role of epigenetic modifications - including DNA methylat
Externí odkaz:
https://doaj.org/article/d55208ffdf8c449180a44ca6baa12b36
Publikováno v:
Medicinski Podmladak, Vol 74, Iss 1, Pp 18-24 (2023)
Dysfunctions underlining type 2 diabetes mellitus (DM2) evolution are insulin resistance and beta-cell secretory insufficiency. Practical but reliable beta-cell function (BCF) testing is still elusive. Methods of BCF measurement include the homeostas
Externí odkaz:
https://doaj.org/article/f7cebca9afc140a1bdd4d891e5e40959
Autor:
Candelaria Martín-González, Tomás Martín-Folgueras, Juan Carlos Quevedo-Abeledo, Antonia de Vera-González, Alejandra González-Delgado, Laura de Armas-Rillo, Miguel Á. González-Gay, Iván Ferraz-Amaro
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-7 (2022)
Abstract Background Insulin resistance and beta-cell dysfunction are manifestations of rheumatoid arthritis (RA). Apolipoprotein C-III (ApoC3) has been associated with such insulin resistance and beta-cell dysfunction in the general population. Our p
Externí odkaz:
https://doaj.org/article/8e4c6045360442e2a83612d6d61ac16c
Publikováno v:
Genes and Diseases, Vol 8, Iss 4, Pp 438-447 (2021)
Diabetes is an age-related disease, most of which is type 2 diabetes, and islet β cell dysfunction and insulin resistance are the main mechanisms of type 2 diabetes. Recent studies have revealed that autophagy plays an important role in maintaining
Externí odkaz:
https://doaj.org/article/1695196ebcdf43778372d10e35548354
Akademický článek
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Publikováno v:
JCRPE, Vol 13, Iss 2, Pp 160-169 (2021)
Objective:Characteristics of the glucose response during oral glucose tolerance test (OGTT) may reflect differences in insulin secretion and action. The aim was to examine whether timing of the glucose peak, shape of the glucose curve and their combi
Externí odkaz:
https://doaj.org/article/d7c768cd9654430bb6ee5c7ab02c0b9e
Publikováno v:
Egyptian Journal of Medical Human Genetics, Vol 21, Iss 1, Pp 1-13 (2020)
Abstract Background Many studies have been conducted on the genetic and epigenetic etiology of gestational diabetes mellitus (GDM) in the last two decades because of the disease’s increasing prevalence and role in global diabetes mellitus (DM) expl
Externí odkaz:
https://doaj.org/article/1cfc465f33074a3b824b7b6f74de810d
Autor:
Floris Leenders, Nathalie Groen, Natascha de Graaf, Marten A. Engelse, Ton J. Rabelink, Eelco J. P. de Koning, Françoise Carlotti
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Pancreatic β-cell failure is a critical event in the onset of both main types of diabetes mellitus but underlying mechanisms are not fully understood. β-cells have low anti-oxidant capacity, making them more susceptible to oxidative stress. In type
Externí odkaz:
https://doaj.org/article/50b393711df249ed8ab6d9d9ee96364a