Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Betül Kaya Çavuşoğlu"'
Autor:
Derya Osmaniye, Betül Kaya Çavuşoğlu
Publikováno v:
Süleyman Demirel Üniversitesi Fen-Edebiyat Fakültesi Fen Dergisi, Vol 16, Iss 1, Pp 301-307 (2021)
Alzheimer hastalığı en sık görülen nörodejeneratif hastalıklarıdan biridir. Gelişmiş ülkelerde %70-76 oranla görülen bu hastalığın radikal bir tedaviye sahip olmaması bilim dünyasını bu konu üzerinde çalışmaya yönlendirmekte
Externí odkaz:
https://doaj.org/article/4621756688f446438c5b866476d29a1c
Autor:
Begüm Nurpelin Sağlık, Derya Osmaniye, Ulviye Acar Çevik, Serkan Levent, Betül Kaya Çavuşoğlu, Özlem Atlı Eklioğlu, Yusuf Özkay, Ali Savaş Koparal, Zafer Asım Kaplancıklı
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 1422-1432 (2020)
Many studies have been conducted on the selective inhibition of human monoamine oxidase B (hMAO-B) enzyme using benzylamine-sulphonamide derivatives. Using various chemical modifications on BB-4h, which was reported previously by our team and showed
Externí odkaz:
https://doaj.org/article/5c8f89ef95f14cababecb6d378950914
Autor:
Ulviye Acar Çevik, Begüm Nurpelin Sağlık, Derya Osmaniye, Serkan Levent, Betül Kaya Çavuşoğlu, Abdullah Burak Karaduman, Özlem Atlı Eklioğlu, Yusuf Özkay, Zafer Asım Kaplancıklı
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 1657-1673 (2020)
In this study, some benzimidazole-oxadiazole derivatives were synthesised and tested for their in vitro anticancer activities on five cancer cell lines, including HeLa, MCF7, A549, HepG2 and C6. Their structures were elucidated by IR, 1H-NMR, 13C-NMR
Externí odkaz:
https://doaj.org/article/8d3d80b3ed0b41ec929c75178d5bc4f6
Autor:
Hülya Karaca Gençer, Ulviye Acar Çevik, Betül Kaya Çavuşoğlu, Begüm Nurpelin Sağlık, Serkan Levent, Özlem Atlı, Sinem Ilgın, Yusuf Özkay, Zafer Asım Kaplancıklı
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 732-745 (2017)
Externí odkaz:
https://doaj.org/article/b7ef0a6b8edc42448ae8c1823e730eb9
Autor:
Begüm Nurpelin Sağlık, Derya Osmaniye, Ulviye Acar Çevik, Serkan Levent, Betül Kaya Çavuşoğlu, Yusuf Özkay, Zafer Asım Kaplancıklı
Publikováno v:
Molecules, Vol 25, Iss 18, p 4312 (2020)
Dementia is a neurological condition commonly correlated with Alzheimer’s disease (AD), and it is seen with many other central nervous system (CNS) disorders. The restricted number of medications is not appropriate to offer enough relief to enhance
Externí odkaz:
https://doaj.org/article/3bf7e9affa5a42468fe8c02dd15e2cf3
Autor:
Begüm Nurpelin Sağlık, Osman Cebeci, Ulviye Acar Çevik, Derya Osmaniye, Serkan Levent, Betül Kaya Çavuşoğlu, Sinem Ilgın, Yusuf Özkay, Zafer Asım Kaplancıklı
Publikováno v:
Molecules, Vol 25, Iss 18, p 4342 (2020)
Monoamine oxidase (MAO) isoenzymes are very important drug targets among neurological disorders. Herein, novel series of thiazolylhydrazine-piperazine derivatives were designed, synthesized and evaluated for their MAO-A and -B inhibitory activity. Th
Externí odkaz:
https://doaj.org/article/4d77e513dadf41a8933679f0bae16c46
Autor:
Begüm Nurpelin Sağlık, Serkan Levent, Derya Osmaniye, Ulviye Acar Çevik, Betül Kaya Çavuşoğlu, Yusuf Özkay, Ali Savaş Koparal, Zafer Asım Kaplancıklı
Publikováno v:
Crystals, Vol 10, Iss 8, p 637 (2020)
Alzheimer’s disease (AD) is a progressive and neurodegenerative disease that is primarily seen in the elderly population and is clinically characterized by memory and cognitive impairment. The importance of the disease has increased as a result of
Externí odkaz:
https://doaj.org/article/6d6081105bd047eba9e00b795c072bac
Autor:
Ulviye Acar Çevik, Betül Kaya Çavuşoğlu, Begüm Nurpelin Sağlık, Derya Osmaniye, Serkan Levent, Sinem Ilgın, Yusuf Özkay, Zafer Asım Kaplancıklı
Publikováno v:
Molecules, Vol 25, Iss 7, p 1642 (2020)
In the last step of estrogen biosynthesis, aromatase enzyme catalyzes the conversion of androgens to estrogens. Aromatase inhibition is an important way to control estrogen-related diseases and estrogen levels. In this study, sixteen of benzimidazole
Externí odkaz:
https://doaj.org/article/db1d871726b443aaade27af80f3b145b
Autor:
Derya Osmaniye, Begüm Nurpelin Sağlık, Ulviye Acar Çevik, Serkan Levent, Betül Kaya Çavuşoğlu, Yusuf Özkay, Zafer Asım Kaplancıklı, Gülhan Turan
Publikováno v:
Molecules, Vol 24, Iss 13, p 2392 (2019)
Alzheimer’s disease (AD) is the most common of the degenerative brain diseases and is described together with the impairment of cognitive function. Patients with AD lose the capability to code new memories, and life conditions are extremely difficu
Externí odkaz:
https://doaj.org/article/2a623e680c474c6aa182e1e80e0904d0
Autor:
Ahmet Çağrı Karaburun, Betül Kaya Çavuşoğlu, Ulviye Acar Çevik, Derya Osmaniye, Begüm Nurpelin Sağlık, Serkan Levent, Yusuf Özkay, Özlem Atlı, Ali Savaş Koparal, Zafer Asım Kaplancıklı
Publikováno v:
Molecules, Vol 24, Iss 1, p 191 (2019)
Discovery of novel anticandidal agents with clarified mechanisms of action, could be a rationalist approach against diverse pathogenic fungal strains due to the rise of resistance to existing drugs. In support to this hypothesis, in this paper, a ser
Externí odkaz:
https://doaj.org/article/312e4797704247aea43c0d3f2bad17de