Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Betânia Lucena Domingues, Hatzlhofer"'
Autor:
Fernanda Silva Medeiros, Taciana Furtado de Mendonça, Katiuscia Araújo de Miranda Lopes, Laís Medeiros da Câmara França, Andreia Soares da Silva, Luydson Richardson Silva Vasconcelos, Maria do Carmo Valgueiro Costa de Oliveira, Ana Cláudia Mendonça dos Anjos, Betânia Lucena Domingues Hatzlhofer, Marcos André Cavalcanti Bezerra, Aderson da Silva Araújo, Patrícia Moura, Maria do Socorro de Mendonça Cavalcanti
Publikováno v:
Genetics and Molecular Biology, Vol 40, Iss 3, Pp 600-603 (2017)
Abstract Sickle cell anemia (SCA) presents heterogenous clinical manifestations that cannot be explained solely by alterations to hemoglobin (Hb); other components such as endothelial adhesion, thrombosis and inflammation may be involved. The mannose
Externí odkaz:
https://doaj.org/article/8d6b488b9ac8486bbb5511d9e9285af2
Autor:
Isabela Cristina Cordeiro Farias, Taciana Furtado Mendonça-Belmont, Andreia Soares Silva, Kleyton Palmeira do Ó, Felipe Borba Ferreira, Fernanda Silva Medeiros, Luydson Richardson Silva Vasconcelos, Moacyr Jesus Barreto de Melo Rego, Marcos Andre Cavalcanti Bezerra, Aderson Silva Araujo, Patricia Muniz Mendes Freire Moura, Ana Claudia Mendonça Anjos, Betânia Lucena Domingues Hatzlhofer, Maria do Socorro Mendonça Cavalcanti
Publikováno v:
Mediterranean Journal of Hematology and Infectious Diseases, Vol 10, Iss 1, Pp e2018012-e2018012 (2018)
The SOD2 polymorphism Val16Ala TàC influences the antioxidative response. This study investigated the association of the SOD2 polymorphism and superoxide dismutase (SOD) activity with vaso-occlusive crisis (VOC) and acute splenic sequestration (ASS)
Externí odkaz:
https://doaj.org/article/220c2cdedcd54e38b11c63368f113e61
Autor:
Ana Caroline Novaes Soares, Isabella Chagas Samico, Aderson Silva Araújo, Marcos André C. Bezerra, Betânia Lucena Domingues Hatzlhofer
Publikováno v:
Revista Brasileira de Hematologia e Hemoterapia, Vol 36, Iss 4, Pp 250-255 (2014)
OBJECTIVE: To determine the geographical distribution of hemoglobinopathies in the State of Pernambuco, to characterize the children with these diseases and to describe factors associated with their follow-up at the referral center during the period
Externí odkaz:
https://doaj.org/article/d78b7c2acc0346ff9d1d494bbaca20a7
Autor:
Manuela F. Hazin, Thais Helena Chaves Batista, Gabriela da Silva Arcanjo, Aderson S Araujo, Betânia Lucena Domingues Hatzlhofer, Antonio R. Lucena-Araujo, Diego Arruda Falcão, Jéssica Vitória Gadelha de Freitas Batista, Pablo Ramon Gualberto Cardoso, Maira Galdino da Rocha Pitta, Marcos André Cavalcanti Bezerra, Diego A Pereira-Martins, Igor de Farias Domingos, Fernando Ferreira Costa, Ana Claudia Mendonça dos Anjos, Isabel Weinhäuser
Publikováno v:
Annals of Hematology. 100:1921-1927
The clinical and phenotypic heterogeneity of patients with sickle cell anemia (SCA) is influenced by environmental and genetic factors. Several genetic modifiers, such as the KLOTHO (KL) gene, have been associated with SCA clinical outcomes. The KL g
Autor:
Marcondes José de Vasconcelos Costa Sobreira, Aderson S Araujo, Antonio R. Lucena-Araujo, Flávia Peixoto Albuquerque, Isabela Cristina Cordeiro Farias, Danízia Menezes de Lima Silva, Diego A Pereira-Martins, Manuela Albuquerque de Melo, Bruna Vasconcelos de Ancântara, Gabriela da Silva Arcanjo, Diego Arruda Falcão, Ana Claudia Mendonça dos Anjos, A. S. Araújo, Magnun N. N. Santos, Rodrigo Marcionilo Santana, Thais Helena Chaves Batista, Isabel Weinhäuser, Jéssica Vitória Gadelha de Freitas Batista, Betânia Lucena Domingues Hatzlhofer, Ana Beatriz Lucas de Moura Rafael, Luana Priscilla Laranjeira Prado, Igor de Farias Domingos, Fernando Ferreira Costa, Marcos André Cavalcanti Bezerra, Juan L Coelho-Silva, Jéssica Maria Florencio Oliveira
Publikováno v:
Annals of Hematology. 100:921-931
Alpha thalassemia and beta-globin haplotype are considered classical genetic disease modifiers in sickle cell anemia (SCA) causing clinical heterogeneity. Nevertheless, their functional impact on SCA disease emergence and progression remains elusive.
Autor:
Gabriela da Silva Arcanjo, Antonio R. Lucena-Araujo, Marcondes José de Vasconcelos Costa Sobreira, Jéssica Vitória Gadelha de Freitas Batista, Aderson S Araujo, Igor de Farias Domingos, A. S. Araújo, Magnun N. N. Santos, Thais Helena Chaves Batista, Jéssica Maricelly Deodato de Oliveira, Marcos André Cavalcanti Bezerra, Fernanda Silva Medeiros, Diego A Pereira-Martins, Diego Arruda Falcão, Flávia Peixoto Albuquerque, Ana Claudia Mendonça dos Anjos, Manuela F. Hazin, Dulcineia M. Albuquerque, Luana Priscilla Morais Laranjeira, Betânia Lucena Domingues Hatzlhofer, Fernando Ferreira Costa, Rodrigo Marcionilo Santana
Publikováno v:
Annals of Hematology. 100:903-911
Hyperbilirubinemia in patients with sickle cell anemia (SCA) as a result of enhanced erythrocyte destruction, lead to cholelithiasis development in a subset of patients. Evidence suggests that hyperbilirubinemia may be related to genetic variations,
Autor:
Taciana Furtado de Mendonça Belmont, Kleyton Palmeira do Ó, Andreia Soares da Silva, Kamila de Melo Vilar, Fernanda Silva Medeiros, Luydson Richardson Silva Vasconcelos, Ana Claudia Mendonça Dos Anjos, Betânia Lucena Domingues Hatzlhofer, Maíra Galdino da Rocha Pitta, Marcos André Cavalcanti Bezerra, Aderson da Silva Araújo, Moacyr Jesus Barreto de Melo Rego, Patrícia Moura, Maria do Socorro Mendonça Cavalcanti
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162297 (2016)
INTRODUCTION:Patients with sickle cell anemia (SCA) may present chronic hemolytic anemia, vaso-occlusion and respiratory tract infection (RTI) episodes. Galectin-3 (GAL-3) is a multifunctional protein involved in inflammation, apoptosis, adhesion and
Externí odkaz:
https://doaj.org/article/b76fc6fdf9364d74b98985bbdfab4927
Autor:
Betânia Lucena Domingues, Hatzlhofer, Diego Antonio, Pereira-Martins, Igor, de Farias Domingos, Gabriela da Silva, Arcanjo, Isabel, Weinhäuser, Diego Arruda, Falcão, Isabela Cristina Cordeiro, Farias, Jéssica Vitória Gadelha, de Freitas Batista, Luana Priscilla Laranjeira, Prado, Jéssica Maria Florencio, Oliveira, Thais Helena Chaves, Batista, Marcondes José de Vasconcelos Costa, Sobreira, Rodrigo Marcionilo, de Santana, Amanda Bezerra de Sá, Araújo, Manuela Albuquerque, de Melo, Bruna Vasconcelos, de Ancântara, Juan Luiz, Coelho-Silva, Ana Beatriz Lucas, de Moura Rafael, Danízia Menezes, de Lima Silva, Flávia Peixoto, Albuquerque, Magnun Nueldo Nunes, Santos, Ana Cláudia, Dos Anjos, Fernando Ferreira, Costa, Aderson, da Silva Araújo, Antonio Roberto, Lucena-Araújo, Marcos André Cavalcanti, Bezerra
Publikováno v:
Annals of hematology. 100(4)
Alpha thalassemia and beta-globin haplotype are considered classical genetic disease modifiers in sickle cell anemia (SCA) causing clinical heterogeneity. Nevertheless, their functional impact on SCA disease emergence and progression remains elusive.
Autor:
Betânia Lucena Domingues Hatzlhofer, Aderson S Araujo, Isabela Cristina Cordeiro Farias, Antonio R. Lucena-Araujo, Ana Karla da Silva Freire, Andreia Soares da Silva, Gabriela da Silva Arcanjo, Kleyton Palmeira do Ó, Maria do Socorro de Mendonça Cavalcanti, Patrícia Muniz Mendes Freire de Moura, Luydson Richardson Silva Vasconcelos, Taciana Furtado Mendonça-Belmont, Diego Arruda Falcão, Marcos André Cavalcanti Bezerra
Publikováno v:
Research, Society and Development, Vol 9, Iss 9 (2020)
Research, Society and Development; Vol. 9 No. 9; e442997314
Research, Society and Development; Vol. 9 Núm. 9; e442997314
Research, Society and Development; v. 9 n. 9; e442997314
Research, Society and Development
Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
Research, Society and Development; Vol. 9 No. 9; e442997314
Research, Society and Development; Vol. 9 Núm. 9; e442997314
Research, Society and Development; v. 9 n. 9; e442997314
Research, Society and Development
Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
Objective: This study aimed to evaluate whether the single nucleotide polymorphisms (SNPs) +191 C>A (rs4644) and +292 A>C (rs4652) of the LGALS3 gene and the serum levels of galectin-3 (gal-3) are associated with clinical events in patients with sick
Autor:
Betânia Lucena Domingues Hatzlhofer, Taciana Furtado Mendonça-Belmont, Antonio R. Lucena-Araujo, Igor de Farias Domingos, João Victor Cordeiro Farias, Marcos André Cavalcanti Bezerra, Maria do Socorro de Mendonça Cavalcanti, Isabela Cristina Cordeiro Farias, Luydson Richardson Silva Vasconcelos, Patrícia Muniz Mendes Freire de Moura, Diego Arruda Falcão, Aderson S Araujo, Gabriela da Silva Arcanjo, Kleyton Palmeira do Ó, Andreia Soares da Silva, Ana Claudia Mendonça dos Anjos
Publikováno v:
Research, Society and Development, Vol 9, Iss 7, Pp e439974240-e439974240 (2020)
Research, Society and Development; Vol. 9 No. 7; e439974240
Research, Society and Development; Vol. 9 Núm. 7; e439974240
Research, Society and Development; v. 9 n. 7; e439974240
Research, Society and Development
Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
Research, Society and Development; Vol. 9 No. 7; e439974240
Research, Society and Development; Vol. 9 Núm. 7; e439974240
Research, Society and Development; v. 9 n. 7; e439974240
Research, Society and Development
Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
Objective: This study has as objective to verify whether MBL2 gene polymorphisms are related to the occurrence of cerebrovascular disease (CD) in sickle cell anemia (SCA) patients. Methods: Overall, 259 unrelated SCA patients were enrolled. The patie