Designing A Pathogen-Focused Study To Address The High Unmet Medical Need Represented By Carbapenem-Resistant Gram-Negative Pathogens – The International, Multicenter, Randomized, Open-Label, Phase 3 CREDIBLE-CR Study

Autor: Bassetti M, Ariyasu M, Binkowitz B, Nagata TD, Echols RM, Matsunaga Y, Toyoizumi K, Doi Y

Publikováno v: Infection and Drug Resistance, Vol Volume 12, Pp 3607-3623 (2019)

Matteo Bassetti,1,2 Mari Ariyasu,3 Bruce Binkowitz,4 Tsutae Den Nagata,3 Roger M Echols,5 Yuko Matsunaga,4 Kiichiro Toyoizumi,4 Yohei Doi6 1Infectious Diseases Clinic, Department of Medicine, University of Udine and Azienda Sanitaria Universitaria In

Externí odkaz: https://doaj.org/article/0d5a1e13a1f3448aad81157a1afa39a1

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Effect and Safety of Meropenem-Vaborbactam versus Best-Available Therapy in Patients with Carbapenem-Resistant Enterobacteriaceae Infections: The TANGO II Randomized Clinical Trial

Autor: Michael N. Dudley, Jihad Bishara, George L. Daikos, Matteo Bassetti, Amy J. Mathers, Jeffery Loutit, Galia Rahav, Jose A. Vazquez, David E. Griffith, Keith S Kaye, Shu Zhang, Richard G. Wunderink, Evangelos J. Giamarellos-Bourboulis, Tanaya Bhowmick, Oliver A. Cornely, Olga Lomovskaya, Timothy Felton, Joseph S. Solomkin, Francesco Menichetti, Maria Jose Lopez Furst, Elizabeth Alexander, Eun J. Kwak, Ilana Oren

Publikováno v: Infectious Diseases and Therapy, Vol 7, Iss 4, Pp 439-455 (2018)
Infectious Diseases and Therapy
Wunderink, R G, Giamarellos-Bourboulis, E J, Rahav, G, Mathers, A J, Bassetti, M, Vazquez, J, Cornely, O A, Solomkin, J, Bhowmick, T, Bishara, J, Daikos, G L, Felton, T, Furst, M J L, Kwak, E J, Menichetti, F, Oren, I, Alexander, E L, Griffith, D, Lomovskaya, O, Loutit, J, Zhang, S, Dudley, M N & Kaye, K S 2018, ' Effect and Safety of Meropenem-Vaborbactam versus Best-Available Therapy in Patients with Carbapenem-Resistant Enterobacteriaceae Infections : The TANGO II Randomized Clinical Trial ', Infectious diseases and therapy . https://doi.org/10.1007/s40121-018-0214-1

Introduction Treatment options for carbapenem-resistant Enterobacteriaceae (CRE) infections are limited and CRE infections remain associated with high clinical failure and mortality rates, particularly in vulnerable patient populations. A Phase 3, mu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::358dd5f268beecda29dcf910a4c993bc
http://hdl.handle.net/11568/946379

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