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Akademický článek

Evaluating the consistency of gene sets used in the analysis of bacterial gene expression data

Autor: Tintle Nathan L, Sitarik Alexandra, Boerema Benjamin, Young Kylie, Best Aaron A, DeJongh Matthew

Publikováno v: BMC Bioinformatics, Vol 13, Iss 1, p 193 (2012)

Abstract Background Statistical analyses of whole genome expression data require functional information about genes in order to yield meaningful biological conclusions. The Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) are com

Externí odkaz: https://doaj.org/article/09bfa3c0b2fa486090c46f45d1e05bc8

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Akademický článek

Gene set analyses for interpreting microarray experiments on prokaryotic organisms

Autor: Heffron Fred, Van Bruggen Dirk, DeJongh Matthew, Best Aaron A, Tintle Nathan L, Porwollik Steffen, Taylor Ronald C

Publikováno v: BMC Bioinformatics, Vol 9, Iss 1, p 469 (2008)

Abstract Background Despite the widespread usage of DNA microarrays, questions remain about how best to interpret the wealth of gene-by-gene transcriptional levels that they measure. Recently, methods have been proposed which use biologically defined

Externí odkaz: https://doaj.org/article/b62d58ddc8a141f388c71375932a5d01

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Akademický článek

The RAST Server: Rapid Annotations using Subsystems Technology

Publikováno v: BMC Genomics, Vol 9, Iss 1, p 75 (2008)

Abstract Background The number of prokaryotic genome sequences becoming available is growing steadily and is growing faster than our ability to accurately annotate them. Description We describe a fully automated service for annotating bacterial and a

Externí odkaz: https://doaj.org/article/5cde187e56664b6d9716978b22e1144b

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Akademický článek

Toward the automated generation of genome-scale metabolic networks in the SEED

Autor: Gould John, Boillot Paul, Formsma Kevin, DeJongh Matthew, Rycenga Matthew, Best Aaron

Publikováno v: BMC Bioinformatics, Vol 8, Iss 1, p 139 (2007)

Abstract Background Current methods for the automated generation of genome-scale metabolic networks focus on genome annotation and preliminary biochemical reaction network assembly, but do not adequately address the process of identifying and filling

Externí odkaz: https://doaj.org/article/c59e5602d5264546bd0083162bcb9116

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